Pharm D Last 12 Years 2010-2022 Question Papers (1st Year, 2nd Year, 3rd Year, 4th Year and 5th Year)
[LN 827] OCTOBER 2018 Sub. Code: 3827
PHARM. ‘D’ AND PHARM. ‘D’ (POST BACCALAUREATE) DEGREE EXAMINATION
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(2009-2010 Regulation)
FIFTH YEAR
PAPER III - CLINICAL PHARMACOKINETICS & PHARMACOTHERAPEUTIC DRUG MONITORING
Q.P. Code : 383827
Time : Three hours Maximum : 70 Marks
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- I. Elaborate on: (4 x 10 =40)
- Explain pharmacokinetic drug interactions with examples.
- Genetic polymorphism in cytochrome P450 ISO enzymes.
- Pharmacokinetic changes and dose adjustment in Hepatic disease.
- Dose adjustment for renal failure and uremic patients.
- II. Write notes on: (6x5=30)
- Importance of Bayesian theory.
- Write brief note on personalized medicine or therapy.
- Drug dosing in paediatrics.
- Nonlinear mixed effect model.
- TDM of seizure drugs.
- Dosing in obese patients.
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