Download MBBS Anatomy PPT 15 Conective Tissues Notes

Connective Tissues

Functions of connective tissue

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Components : Fibres and Cells

Classification of connective tissue

Four basic types of tissue

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Epithelium

Connective tissue

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Connective tissue proper

Cartilage

Bone

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Blood

Muscle tissue
Nervous tissue

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Classes of Connective Tissue

Connective Tissue

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Function:

to protect,

support

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bind

Bones, ligaments, tendons

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Areolar cushions; adipose insulates and is food

source

Blood cells replenished; body tissues repaired

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extracellular matrix


Basic functions of connective tissue

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Support and binding

Holding body fluids

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Defense : macrophages, plasma cells,

mast cells, WBCs

Storing nutrients as fat

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Extracellular Matrix
Nonliving

By cells and then extruded

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strength

Two components

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1.

Ground substance

Connective tissue fluid, adhesion

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proteins, proteoglycans

Liquid, semisolid, gel-like or very hard

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2.

Fibers: collagen, elastic or reticular

MESENCHYME

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Embryonic

Gel-like ground

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substance :

fibres and star
shaped cells.

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Gives rise to all

other connective
tissue types.

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Umbilical cord


Connective tissue fibres

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Collagen

dominant fibre type

add strength to the connective tissue.

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thickness ~ 1 to 10 ?m

microfibrils

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tropocollagen

Collagen fibres

H&E

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Collagen

Types I-XXV based on aminoacids

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Commonest types:

a) I- dermis, tendon, ligaments, bone

b) II- hyaline cartilage, elastic cartilage

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c) III- reticular fibres- lymph node, spleen, bone marrow

d) IV- basal lamina

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e) V- Foetal membranes, blood vessels

Reticular fibres

delicate network -

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branching fibres

larger than fibrocyte

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nuclei - typically large -

lightly stained with H&E

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Elastic fibres

Run singly, branch

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and anastomose.

Elastin, Fibrillin,

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Desmosin

Fine, dark violet and

gently undulating

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fibres in the tissue.

Connective tissue cells

Fibroblasts--Fibrocytes

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Adipocytes

Macrophages/ histiocytes

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Fibroblast

Adipose tissue

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Brown adipose vs White adipose

Macrophage

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Mast cells

Plasma cells

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Leukocytes

Mast cell

Plasma cell

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Classification of connective tissue

Loose Connective tissue

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Areolar

Adipose

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Reticular

Dense connective tissue

Irregular

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Regular

Elastic

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Loose connective tissue, areolar

Loose connective tissue, adipose

Loose connective tissue, reticular

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Dense connective tissue, irregular

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Dense connective tissue, regular

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