Download MBBS Anatomy PPT 15 Conective Tissues Notes

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Connective Tissues

Functions of connective tissue

Components : Fibres and Cells

Classification of connective tissue

Four basic types of tissue

Epithelium

Connective tissue

Connective tissue proper

Cartilage

Bone

Blood

Muscle tissue
Nervous tissue

Classes of Connective Tissue

Connective Tissue

Function:

to protect,

support

bind

Bones, ligaments, tendons

Areolar cushions; adipose insulates and is food

source

Blood cells replenished; body tissues repaired

extracellular matrix


Basic functions of connective tissue

Support and binding

Holding body fluids

Defense : macrophages, plasma cells,

mast cells, WBCs

Storing nutrients as fat

Extracellular Matrix
Nonliving

By cells and then extruded

strength

Two components

1.

Ground substance

Connective tissue fluid, adhesion

proteins, proteoglycans

Liquid, semisolid, gel-like or very hard

2.

Fibers: collagen, elastic or reticular

MESENCHYME

Embryonic

Gel-like ground

substance :

fibres and star
shaped cells.

Gives rise to all

other connective
tissue types.

Umbilical cord


Connective tissue fibres

Collagen

dominant fibre type

add strength to the connective tissue.

thickness ~ 1 to 10 ?m

microfibrils

tropocollagen

Collagen fibres

H&E

Collagen

Types I-XXV based on aminoacids

Commonest types:

a) I- dermis, tendon, ligaments, bone

b) II- hyaline cartilage, elastic cartilage

c) III- reticular fibres- lymph node, spleen, bone marrow

d) IV- basal lamina

e) V- Foetal membranes, blood vessels

Reticular fibres

delicate network -

branching fibres

larger than fibrocyte

nuclei - typically large -

lightly stained with H&E




Elastic fibres

Run singly, branch

and anastomose.

Elastin, Fibrillin,

Desmosin

Fine, dark violet and

gently undulating
fibres in the tissue.

Connective tissue cells

Fibroblasts--Fibrocytes

Adipocytes

Macrophages/ histiocytes

Fibroblast

Adipose tissue




Brown adipose vs White adipose

Macrophage

Mast cells

Plasma cells

Leukocytes

Mast cell

Plasma cell


Classification of connective tissue

Loose Connective tissue

Areolar

Adipose

Reticular

Dense connective tissue

Irregular

Regular

Elastic

Loose connective tissue, areolar

Loose connective tissue, adipose

Loose connective tissue, reticular




Dense connective tissue, irregular

Dense connective tissue, regular

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