Histology of Cartilage
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Learning objectives? To know the types of cartilage and their location in body.
? To know the salient histological features of each type of cartilage.
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? To be able to identify cartilage in a histology slide.
Classes of Connective Tissue
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Cartilage? Specialised Connective
tissue :
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A. Cells
B. Extracellular components.
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? No vessels or nerves.? Perichondrium present
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Extracellular matrix
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Ground substance? Hyaluronan
? chondroitin sulfates
? keratan sulfate
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? Tropocollagen? Collagen type II
Types of cartilages
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? Hyaline cartilage? Elastic cartilage
? Fibrocartilage
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Hyaline cartilage
? Isogenous groups of chondrocytes
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? Territorial matrix? Interterritorial matrix
Elastic Cartilage
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Located in
? epiglottis cartilage
? corniculate
? cuneiform cartilage
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? external ear? auditory tube.
? Elastic fibres
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? Maintains shapeFibrous Cartilage
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? Transitional? Chondrocytes lie in short rows.
? Perichondrium difficult to define.
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Articular Cartilage
? Specialised form of hyaline
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cartilage.? Covers articulating ends of the
bones
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Lubrication
wear-proof
slightly compressible
exhibit very little friction.
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? No perichondrium and is partly
vascularized.
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LayersGrowth in cartilages
? Appositional growth ?
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? Interstitial growth ?
isogenous cells nest
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Identify