Learning Objectives
1. Median nerve formation , root value and important
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relations2. Motor and sensory supply
3. Important sites of injuries/entrapment of nerve
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4. Effects of injury of median nerve
5. How to clinically test median nerve injury
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Q 1.Regarding the median nerve, all are correctEXCEPT:
a. Arises from both the medial and lateral cords of the
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brachial plexus.
b. It crosses the brachial artery at the insertion of the
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coracobrachialis.c. In the cubital fossa, it lies lateral to the brachial
artery.
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d. It enters the hand in the carpal tunnel.
e. Injury of the nerve causes ape-like hand.
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Q 1.Regarding the median nerve, all are correctEXCEPT:
a. Arises from both the medial and lateral cords of the
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brachial plexus.
b. It crosses the brachial artery at the insertion of the
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coracobrachialis.c. In the cubital fossa, it lies lateral to the brachial
artery.
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d. It enters the hand in the carpal tunnel.
e. Injury of the nerve causes ape-like hand.
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Answer cQ 2. A 40 year tailor complains of pain numbness and weakness of right hand for last 3
months. On examination, there is hypoesthesia and atrophy of thenar eminence.
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Which of the following nerve is likely to be involved?
A Ulnar nerve
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B Median nerveC radial nerve
D Axil ary nerve
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Q 3 Injury to the median nerve in the arm would affect al of the following movements
except:
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A. Pronation of the forearm
B. Flexion of the wrist
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C. Flexion of the thumbD. Supination of the forearm
Anatomy
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? Mixed nerve (contain motor & sensory fibers).
? Root value: C 5,6,7,8 & T1
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? Runs in the median plane of the forearm , soits called median nerve
MEDIAN NERVE
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? Formation:from two roots from
lateral cord
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[C(5),6,7]&from medial cord(C8,T1) of
brachial plexus
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Before leaving axil a, C7 fibres
conveyed by median nerve are
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handed over to Ulnar nerve? These two roots embrace the third
part of axillary artery uniting
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anterior or lateral to it
In the arm
? Closely related to the
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brachial artery through out
the course in arm
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? In the upper part it islateral to artey
? In the middle part it
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crosses the artery from
lateral to medial side
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? Remains on the medialside up to elbow
Branches in arm
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? Branch to Pronator Teres just above elbow
? Branch to brachial artery
? Branch to elbow joint at or just below the
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elbowIn the cubital fossa
? Descends medial to
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brachial artery
? Posterior to bicipital
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aponeurosis? Anterior to brachialis,
seperated by the
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muscle from the elbow
joint
? Leaves the cubital fossa by passing
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between two heads of pronator teres
In the forearm
? Enters the forearm between
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the heads of pronator teres
? Crosses the lateral side of
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ulnar artery from which it isseperated by the deep head
of pronator teres
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? Gives branch to pronator
teres while passing between
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the two heads? Proceeds behind a
tendinous ridge
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between the two heads
of Flexor digitorum
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superficialis andanterior to Flexor
digitorum profundus
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? Here it is accompanied
by median artery, a
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branch of anteriorinterosseous artery
? About 5 cm
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proximal to flexor
retinaculum it
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becomessuperficial
? Here it lies
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between the
tendon of
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palmaris longusand the flexor
carpi radialis
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muscle
? Leaves the forearm and enters the palm of the
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hand by passing through the carpal tunnel deep toflexor retinaculum
Branches in the forearm
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? Muscular branchesto all the muscles
in the
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superficial and
intermediate layer of
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forearm except one(FCU) originate
medially from nerve
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just distal to elbow
joint
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? Anterior interosseousnerve: originate between
two heads of pronator teres
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? passes distally down the
forearm with the anterior
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interosseous artery.? Innervates the muscles of
deep layer (FPL, lateral half
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of FDP (for index and middle
finger) and pronator
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quadratus)Articular Branches -supply
elbow,superior and inferior
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radio-ulnar joint, interosseous
membrane and wrist joint
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?Palmar cutaneous branch: starts just proximal to flexorretinaculum
?Lateral branches - thenar skin and connecting branch to
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the lateral cutaneous nerve of fore arm
?Medial branches - central palmer skin and connecting
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branch to the palmar cutaneous branch of the ulnar nerve? Communicating branch:
multiple
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?Arise in the proximal forearm
? Pass medialy between FDP &
FDS and behind the ulnar artery
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to join the ulnar nerve
Median nerve in hand
? Proximal to flexor retinaculum it lies
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between the tendons of FCR & FDS
overlapped by palmaris longus
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? Distally it lies between the retinaculum andthe tendon in the retinaculum
? Site of compression
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? Distal to retinaculum nerve enlarges and
flattens
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? devides in to five or six branchesBranches in the hand
Lateral branch: gives
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Recurrent
muscular branch-
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short andstout, curls upwards
over the distal border
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of flexor retinaculum
and FPL to supply
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three thenar musclesAPB, FPB &OP
? Three palmer digital
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branches- First two
supply the skin of the
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sides of the thumb ,itsweb and distal part of
its dorsal surface.
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? Third supplies the skin
of the radial side of
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index finger and thefirst lumbrical muscle
through its superficial
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surface
? Medial branch: gives
? Two common palmar digital
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branches- lateral and
medial which descend to
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the interdigital cleftsbetween the index, middle
and ring finger
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? Each nerve divides again
into two to supply adjacent
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sides of the fingers? So in total it supplies skin of
lateral three and half fingers
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including the skin on the
dorsal aspect of terminal
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phalangesInjuries
? High
? Low
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Median Nerve Lesion in Elbow Region ? High Lesion
? Damaged in
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supracondylar fractureof humerus
? Muscles af ected are:
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? Pronator muscles ofthe forearm
? All long flexors of
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wrist and fingers
except FCU and
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medial half of FDPMotor Effects:
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Wastingof thenar
? Loss of pronation. Hand is kept in
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eminence
supine position
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? Wrist shows weak flexion, andulnar deviation
? Loss of flexion on interphalangeal
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joints of the index and middle
fingers
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? Weak flexion of ring and littlefinger
Ulnar deviation
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? Thumb is adducted and lateral y
rotated, with loss of flexion of
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terminal phalanx and loss ofopposition
? Wasting of thenar eminence
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? Hand looks flat ened and
"apelike", and presents an inability
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to flex three most radial digitswhen asked to make a fist.
? Sensory Ef ects: Loss of
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sensation from:
? The radial side of the palm
? Palmar aspect of the lateral
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3? fingers
? Distal part of the dorsal
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surface of the lateral 3?fingers
? Trophic Changes:
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? Dry and scaly skin
? Easily cracking nails
? Atrophy of the pulp of
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fingersMedian Nerve Lesion at Wrist
? Often injured by penetrating wounds (stab wounds or
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broken glass) of the forearm.
? Motor:
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? Thenar muscles are paralyzed and atrophy in time so thenareminence becomes flattened
? Opposition & abduction of thumb are lost, and thumb and
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lateral two fingers are arrested in adduction & hyperextension
position .
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? "Apelike hand"? Sensory & trophic changes are same as in elbow
region injuries
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Examination
? Flexor pol icis longus : Tested by holding
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thumb at its base and patient asked to flex theterminal phalanx
Examination
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? Flexor digitorum superficialis & profundus
(Ochsner's clasping test)
- Patient is asked to clasp the hands , the index
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finger of af ected side fails to flex
Examination
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? Flexor Carpi radialis : Hand deviates to theulnar side when flexed against resistance
Examination
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? Muscles of Thenar eminance:
-abductor pol icis brevis (Pen test)
- hand laid flat on the table
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-pen held above the palm and the patient isasked to touch the pen with his thumb
Examination
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? opponens pol icis : brings the tip of thethumb towards the tips of other fingers
Opponens pollices
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Benedict Sign
Lesion to upper arm area, just proximal to where motor
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branches of forearm flexors originate, is diagnosed if thepatient is unable to make a fist.
More specifically, the patient's index and middle finger
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cannot flex at the MCP joint, while the thumb usually is
unable to oppose. This is known as hand of benediction or
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Pope's blessing hand.Benedict Sign
Kiloh-Nevin syndrome and OK Sign
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The Anterior Interosseus Nerve (AIN) syndromePatients suffering from this syndrome have impaired distal
interphalangeal joint, because of which they are unable to
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pinch anything or make and "OK" sign with their index finger
and thumb. The syndrome can either happen from pinched
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nerve, or even dislocation of the elbow.Kiloh-Nevin syndrome OK Sign
After history of stab wound on front of forearm , patient
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presents with impairment of the pincer movement and is having
difficulty picking up a small item, such as a coin, from a flat
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surface. Which of the following statement is correct ?A Injury to anterior interroseous nerve of median nerve
B injury to main median nerve as pincer movement involves FDS
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C Injury to ulnar nerve
D. Injury to median nerve at level of wrist
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Ape hand deformityIn "Ape hand deformity", the thenar muscles become
paralyzed due to impingement and are subsequently flattened.
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it is seen only after the thenar muscles have atrophied. While
the adductor pollicis remains intact, the flattening of the
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muscles causes the thumb to become adducted and laterallyrotated. The opponens pollicis causes the thumb to flex and
rotate medially, leaving the thumb unable to oppose.
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Ape ThumbMedian nerve Compression
Syndromes
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? Carpal Tunnel ?nerve may be compressed due to
inflammatory condition of ulnar bursa or anterior
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dislocation of lunate bone? Pronator
? Interosseous
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Carpal Tunnel Syndrome? Compressive neuropathy as the nerve passes through the
Carpal Tunnel
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? Causes:
- Idiopathic
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: Most common- Inflammatory : Rheumatoid Arthritis
: Wrist osteoarthritis
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- Post traumatic : Bone thickening
- Endocrine
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: Myxoedema: Acromegaly
- Pregnancy
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- Gout
- Repetitive wrist movts: Typists & Computer users
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Carpal Tunnel Syndrome? The commonest neurological
problem associated with median
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nerve is compression beneath
flexor retinaculum at wrist.
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? Motor: Weak motor function ofthumb, index & middle finger
? Sensory: Burning pain or `pins
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and needles' along distribution
of median nerve to lateral 3?
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fingersNo sensory changes over palm as palmer cutaneous branch
is given before median nerve enters carpal tunnel.
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Symptoms? Hand and wrist Pain
? Paraesthesia
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? Hypoaesthsia
? Sparing of Palmar cutaneous branch supply
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? Patient wakes at night with burning or achingpain and shakes the hand to obtain relief and
restore sensation
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? Aggravated by elevation of hand
? Thenar atrophy and weakness of thumb
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opposition and abduction may develop lateDiagnosis
? History
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? Clinical examination:
- Thenar wasting
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- Phalen's sign- Tinel's sign
- Carpal compression test
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? Electro Diagnostic Studies:
- Very reliable for evaluation
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- Atypical cases may be presentThenar atrophy
Phalen test
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A positive Phalen test is highly suggestive of carpal tunnel
syndrome.
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Phalen's test is performed by having patients place their wrists incomplete unforced flexion for at least 30 seconds.
If the median nerve is entrapped at the wrist, this maneuver will
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reproduce the symptoms of carpal tunnel syndrome.
Tinel's Sign
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Carpal Compression test/ Durkan's test
Pronator teres syndrome
? High Compression neuropathy
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? It is rare compared to CTS and AIS
Pronator teres syndrome
The characteristic physical finding is tenderness over the
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proximal median nerve, which is aggravated by resisted
pronation of the forearm.
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The flexor pol icis longus and FDP of the index finger are weak,leading to impairment of the pincer movement. This reflects
involvement of the anterior interosseous nerve.
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Sensory changes may be found in the first three fingers as well
as in the palm, indicating impairment of the median nerve
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proximal to the flexor retinaculum.Symptoms & signs
? Symptoms are similar to those of carpal tunnel syndrome
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? Sensory disturbances
- Thumb & Index > Middle finger
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? Night pain is unusual and forearm pain is more common? Hand numbness on gripping
? Phalen's test negative
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? Double crush phenomena
? Symptoms provoked by resisted elbow flexion with forearm
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supinated ( tightening of bicipital aponeurosis )? By resisted forearm pronation with the elbow extended (
pronator tension )
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