SKIN
DEFINITION
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? GENERAL COVERING OF THE EXTERNAL? SURFACE OF THE BODY
? FORMS 15% OF THE TOTAL BODY WEIGHT
? THICKNESS-1.5 to 5.0 mm
? LARGEST ORGAN OF THE BODY
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INTEGUMENTARY SYSTEM
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Some Facts about Skin? Surface area: 1.5-2.0 sq meters
? Growth rate of nail: 0.1mm per day
? Growth rate of hair: 1.5-2.2 mm per week
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? Life span of hair:Eyelashes, axilla- 4 months
Scalp ? 4 years
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STRUCTURE OF SKIN? TWO DISTINCT LAYERS
* EPIDERMIS
* DERMIS
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? EPIDERMIS : SUPERFICIAL AND AVASCULAR? DERMIS : DEEP AND VASCULAR
TERMS USED FOR MOVEMENTS
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TYPES OF SKIN? THICK SKIN - EPIDERMIS VERY THICK
USUALLY HAIRLESS ON
PALMS OF HAND & SOLES
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OF FEET? THIN SKIN ? COVERS GREATER PART OF
BODY & IS USUALLY HAIRY
? EXCEPTION ? SCALP : THICK AND HAIRY
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Layers Of Skin
Epidermis:
? Composed of keratinized
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stratified squamous epithelium.
Dermis:
? Papillary region composed of
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loose connective tissue.
? Reticular region composed of
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dense irregular connective tissue.Hypodermis:
? Composed of areolar tissue with
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abundant adipocytesCells
? Keratinocytes
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? Melanocytes-pigment forming cells fromneural crest cells
? Merkel cells-sensory mechanoreceptors
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? Langerhans cells-antigen presenting cells frombone marrow
? Free nerve endings
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LAYERS OF THE EPIDERMIS
Stratum Basale (Germinal/
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Malpighian layer):
? Single layer of cuboidal cells resting on
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basement membrane.? High mitotic activity.
Stratum Spinosum:
? Several layers of polygonal cells.
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? Cells are held together bydesmosomes.
Stratum Granulosum:
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? 3-5 layers of flattened polygonal cells.? Cells contain keratohyaline granules.
contd....
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Stratum Lucidum:? Seen only in non-hairy or thick skin.
? Cel s are flattened, translucent,
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eosinophilic with indistinct
boundaries & nucleus.
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? Contains a product ofkeratohyaline i.e. eleidin.
Stratum Corneum:
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? Composed of structureless
dehydrated dead cel s.
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? Flattened & scale-like.? Fil ed with keratin.
? Superficial layer is continuosly
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sloughed off.
Stratum Basale
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Stratum Spinosum
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Stratum GranulosumStratum Lucidum
Stratum Corneum
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SPECIALIZED CELLS OF THE EPIDERMIS
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Keratinocytes:
? Most common cel s of the epidermis.
? Provides protection and
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waterproofing sealant.Melanocytes:
? Rounded cel s with dendrite-like
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branches.? Present in Stratum basale.
? Produces melanin pigment
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responsible for the colour of skin.? Melanin is a brown/black pigment
that absorbs UV-light.
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SPECIALIZED CELLS OF THE EPIDERMIS
Langerhans Cells (antigen presenting
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cells):? Non-pigmented granular dendrocytes.
? Present in Stratum spinosum.
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? Nucleus is indented at many places &
cytoplasm contains rod-shaped
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granules.? They participate in immune responses
against bacteria and viruses.
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Merkel Cells:
? Found in Stratum basale.
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? Sensory cells innervated by sensorynerves.
? Abundant in fingertips, oral mucosa &
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hair follicles.
? Function as mechanoreceptors.
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PIGMENTATION OF SKIN
The colour of skin depends upon fol owing factors:
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? Carotene: yellow-orange pigment (precursor of vitamin A)found in stratum corneum & dermis.
? Melanin: produced in epidermis by melanocytes
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gives black colour to the skin.
? Hemoglobin (in blood vessels of dermis): gives pink colour
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to the skin.LAYERS OF THE DERMIS
?
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Papil ary layer:
-Narrow band of loose connective tissue.
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-In contact with basement membrane ofstratum basale.
-Dermal papil ae (finger- like processes)
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- provide mechanical anchorage and supply
nerves and blood vessels
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?
Reticular layer:
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-
4
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Dense irregular connective tissue.Dermal
papil a
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-Thick elastic fibres.
-may be involved in development of skin lines
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TYPES OF SKIN
Th
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Thin Skinin Skin
Th
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Thick i
Skck
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in SkinLayers of epidermis
St. corneum &
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St. corneum & spinosum are
spinosum are thin while thick while lucidum is
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lucidum is absent.present.
Thickness of epidermis
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0.10-0.15 mm
0.6-4.5 mm
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Epidermal ridgesAbsent
Present (well developed
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dermal paplillae)
Hair fol icles, arrector pili Present
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Absentmuscle & sebaceous
gland
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Sweat glandsFew
Many
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Sensory receptors
Less
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MoreDistribution
Covers all parts of body Present in palms, palmar
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except palms & soles
surface of digits & soles
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APPENDAGES OF THE SKIN
HAIRS:
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? Keratinized filaments derived from
invagination of the basal layer of
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epidermis into the dermis.? Parts-
a) Root: enclosed by hair follicle.
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b) Shaft: projects above the surface.
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? Hair fol icle: tubular invagination,
partly epidermal and partly dermal in
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origin.contd.....
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Structure of shaft and root:
? Medul a
? Cortex
? Cuticle
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Hair fol icle:? Tubular invagination of epidermis
& dermis in which hair root
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resides.? Layers: 3 (inner root sheath, outer
root sheath, connective tissue
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sheath).
contd.....
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? Hair bulb: lower expandedend of hair follicle.
? Hair papil a: the
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indentation at the base of
hair bulb by part of the
dermis.
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contd.....Arrector Pilorum Muscle:
? Smooth muscle innervated
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by sympathetic nerves.
? Extends from papil ary
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layer of dermis to theconnective tissue sheath of
a hair fol icle.
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? Contraction of muscle
presses the sebaceous
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gland which squeezes outsebum.
? Formation of "goose flesh".
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APPENDAGES OF THE SKIN
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NAILS:
? Hardened keratin plates on
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the dorsal surface of thetips of fingers & toes.
? Parts:
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a) Root
b) Free border
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c) Body? Nail bed: tissue on which
the nail rests. Made up of
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stratum basale & spinosum.
APPENDAGES OF THE SKIN
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SEBACEOUS GLANDS:? Distributed all over the
dermis of the skin, except
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for the palms & soles.
? Abundant in the scalp,
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face, around theapertures of the ear, nose,
mouth & anus.
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APPENDAGES OF THE SKIN
SEBACEOUS GLANDS:
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? Holocrine in nature.? Number of alveoli
connected to broad duct
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that opens into hair
follicle.
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? Produces an oilysecretion called sebum.
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SWEAT GLANDS (SUDORIFEROUS GLANDS)? Absent from lips, glans & nail bed.
? Mode of secretion: merocrine
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? Simple tubular gland
? 2 parts:
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(a) Secretory portion(b) Excretory duct
Secretory portion:
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? Twisted coil like structure with simple
cuboidal epithelium.
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? 3 types of cel s: clear cel s, dark cel s,myoepithelial cel s.
Excretory duct:
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? Long & extends from secretory portion to
surface of epidermis.
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contd....2 types:
Eccrine:
? Most numerous in the soles &
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palms.
? Produces thin watery secretion.
Apocrine:
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? Confined to axil a, eyelids (Moll'sglands), nipple & areola of breast,
perianal region, and the external
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genitalia.
? Produces thick odourous secretion.
? Ceruminous glands & lactating
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mammary glands are modified
apocrine sweat glands.
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Sweat GlandSURFACE IRREGULARITIES
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? FLEXURE LINES - Permanent lines alongwhich
the skin folds during habitual
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movements of joints
? CLEAVAGE LINES - According to arrangement
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of fibres in deep fascia, horizontal intrunk, in old age fibres atrophy and skin
wrinkles
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PAPILLARY RIDGES
PAPILLARY RIDGES
? Palms and soles and digits
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? Form narrow ridges separatedby fine paral el grooves,
? corrospond to dermal papil ae
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? Study is cal ed dermatoglypics? Pattern of finger prints- loops ,
whorls and arches and
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compositeLanger's lines(Cleavage lines)
? Langer lines of skin tension, or
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sometimes called cleavage lines
? Correspond to the natural orientation
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of collagen fibers in the dermis,? Are generally parallel to the orientation of
the underlying muscle fibers.
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? Langer's lines have relevance to forensic
science and the development of surgical
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techniquesLanger's lines
? Langer lines of skin tension, or
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sometimes cal ed cleavage
lines
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? Correspond to the naturalorientation of collagen fibers
in the dermis,
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? Are general y paral el to the
orientation of the underlying
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muscle fibers.? Langer's lines have relevance
to forensic science and the
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development of surgical
techniques
Applications of Langer Lines
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? Incisions made parallel to Langer's lines may
heal better and produce less scarring than
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those that cut across. Conversely, incisionsperpendicular to Langer's lines have a
tendency to pucker and remain obvious,
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although sometimes this is unavoidable
? In old age, elastic fibres atrophy and skin
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becomes wrinkledLinea gravidarum
? Rupture of fibre bundles
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of dermis due to
excessive stretching
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result in prominentwhite lines.
? Seen in anterior
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abdominal wall in
pregnancy.
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Rule of Nine: To estimatethe extent of damaged skin
in burn injuries.
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? First degree burn-
only epidermis.
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? Second degree burn-epidermis + upper region of
dermis.
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? Third degree burn-
entire thickness of skin.
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Dermatomes? The strip of skin
supplied by a single
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spinal nerve is called
dermatome.
FUNCTIONS OF SKIN
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? Protective shield for the body
? Barrier to water
? Thermoregulation
? Important sense organ (pain, touch,
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temperature & pressure)
? Absorption of ultraviolet radiation from sun
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for the production of vitamin DAPPLIED ANATOMY
? Skin is pale in anemia, yel ow in
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jaundice and blue in cyanosis? Skin incisions should be made paral el to
lines of cleavage to have the smal est scar
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? Sebaceous cyst is common in scalp
due to obstruction to sebaceous
duct
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SUPERFICIAL FASCIASUPERFICIAL FASCIA
? DEFINITION- General coating of the body
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beneath the skin made up of loose
areolar tissue and fat
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? ABUNDANCE OF FAT- Front of thigh andanterior abdominal wal
? ABSENCE OF FAT- Eyelids & external ear
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? In females there is more fat and it is
evenly distributed
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TERMS USED FOR MOVEMENTSIMPORTANT FEATURES
? Most distinct in lower part of
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anterior abdominal wal & limbs? Very thin on dorsal aspect of hands &
feet, sides of neck, face.
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? Very dense in scalp, palms and soles.IMPORTANT FEATURES
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? IT CONTAINS1. Cutaneous nerves &
vessels
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2. Groups of lymph nodes3. Subcutaneous muscle in
neck
FUNCTIONS
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? Helps in movements of skin
? Allows for the passage of the vessels &
nerves to the skin
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? Conserves body heat as fat is a bad
conductor of heat
? Fat fills hollow spaces like axilla &
orbits
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DEEP FASCIA
? Deep fascia is a fibrous sheet which
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covers the body beneath the superficialfascia.
? It is devoid of fat, and is usual y inelastic
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and toughDISTRIBUTION OF DEEP FASCIA
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? Best seen in limbs where it forms tough andtight sleeves
? Well defined in the neck where it
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? forms a collar? Not well formed on the trunk and face
? Blends with periosteum of a subcutaneous
bone
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MODIFICATIONS OF DEEP FASCIA
? Inter muscular septa which divides limbs
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into compartments? Thickenings form retinacula around joints
like wrist and ankle
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? Forms sheath around large arteries
? In palms & soles form aponeurosis
? Form investing layer of fascia in region of
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neck giving it shape.INTERMUSCULAR SEPTA
RETINACULA
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INVESTING LAYER OF FASCIA
FUNCTIONS
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? Keeps underlying structures in position
? Provides extra surface for muscle
attachment
? Helps in venous return
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? Helps muscles in action by applying tensionand pressure
? Retinacula keep tendons in position
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MCQ
Q1. Which layer is present only in thick skin:
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a. Stratum basaleb. Stratum spinosum
c. Stratum granulosum
d. Stratum lucidum
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MCQQ2. The characteristic feature of reticular layer of
dermis is:
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a. High mitotic activityb. Contains keratin granules
c. Dense irregular connective tissue
d. Finger like processes
MCQ
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Q3. Secretion of sebaceous glands is aided by
contraction of:
a. Arrector pilorum muscle
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b. Myoepithelial cellsc. Papillary layer of dermis
d. Reticular layer of dermis
MCQ
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Q4. Langerhans cells are present in:
a. Stratum basale
b. Stratum spinosum
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c. Stratum granulosumd. Stratum lucidum