Learning Objectives
A Different lobes and surfaces of Cerebral hemisphere
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B. Blood supply of different regions of cerebral hemisphereC Important sulci and gyri
D Different functional areas located in cerebral hemisphere
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E. Lesions and its effects
2
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Cerebrum
Largest part of the brain
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Heavily convoluted bilobedstructure
4
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Cerebral hemispheresGeneral Appearance:
Separated by a deep midline sagittal
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fissure ? longitudinal cerebral fissureIn the depth of the fissure, the corpus
cal osum connects the hemispheres
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across the midline
Gyri ? the folds of the surface of
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hemispheresSulci ? the fissures separate the gyri
5
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Surfaces of Cerebral Hemisphere
Three surfaces:
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Superolateral surfaceInferior surface
Medial surface
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Borders
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1 Superomedial border
2 Superciliary border and inferolateral border
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(Shows preoccipital notch)3. Medial orbital border, hippocampal border or
inferomedial border and medial occipital border
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6
Lobes of Cerebral Hemispheres
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Cerebral hemispheres are divided intolobes by the central, parieto-occipital,
lateral and calcarine sulci
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Lobes are named according to the
cranial bones under which they lie
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Lobes are:Frontal
Parietal
Temporal
Occipital
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8Cerebral hemisphere
? the essential features can be
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1summarized by stating that:-
1. the frontal lobe lies in front of
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the central sulcus (1) and above
2
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the lateral sulcus (2) .3
2. the parietal lobe is behind the
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central sulcus and above the
lateral sulcus.
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3. the temporal lobe is below thelateral sulcus
4. the occipital lobe lies below and
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P
behind the parieto-occipital
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Fsulcus (3) .
O
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T
Main sulci
1
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1. Central sulcus
3
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2. Lateral sulcus3. Parito-occipital sulcus
4. Calcarine sulcus
2
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5. Cingulate sulcus
6. Cal sosal sulcus ( Sulcus
of corpus cal osum )
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7. Orbital sulcus
8. Parahippocampal sulcus
9. Col ateral sulcus
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510. Occipiti-temporal sulcus
6
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- First (6) can be seen in
sagittal sections
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- Last 4 seen only in axial4
sections
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Main sulci
7
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1. Central sulcus2. Lateral sulcus
3. Parito-occipital
sulcus
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4. Calcarine sulcus
5. Cingulate sulcus
6. Cal sosal sulcus (
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Sulcus of corpus10
8
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cal osum )
9
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7. Orbital sulcus8. Parahippocampal
sulcus
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9. Col ateral sulcus10. Occipiti-temporal
sulcus
1. Central sulcus 2. Lateral sulcus 3. Parito-occipital sulcus
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4. Calcarine sulcus5. Cingulate sulcus
6. Cal sosal sulcus ( Sulcus of corpus cal osum )
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1
3
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5 62
4
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2
2. Parahippocampal sulcus
3. Col ateral sulcus
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4. Occipiti-temporal sulcus3
4
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Main gyri1
2
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1. Precentral
3
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2. Postcentral3
4
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3. Frontal (superior, middle & inferior)
3
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4. Parietal (superior & inferior) 5-5
5. Temporal (superior, middle &
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inferior)
5
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6. Cal osal5
7. Medial frontal
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8. Paracentral lobule9. Precuneus
7
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810. Cuneus
6
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11. Lingual gyrus
9
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12. Orbital gyri13. Gyrus rectus
10
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14. Parahippocampal15. Occipitotemporal (medial & lateral)
11
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16. UncusMain gyri
13
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1. Precentral2. Postcentral
12
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3. Frontal (superior, middle & inferior)
4. Parietal (superior & inferior) 5-
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5. Temporal (superior, middle &inferior)
6. Cal osal
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16
7. Medial frontal
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8. Paracentral lobule15
15
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9. Precuneus
14
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10. Cuneus11. Lingual gyrus
12. Orbital gyri
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13. Gyrus rectus
14. Parahippocampal
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15. Occipitotemporal (medial & lateral)16. Uncus
1
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1. Rectus gyrus2. Uncus ( parahippocampus
gyrus )
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23. Hippocampal gyrus
3
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9
Main sulci
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Central sulcusIndents the superior medial border of the
hemisphere, 1 cm behind the mid-point
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It runs downward, forward and toward the
lateral sulcus across the lateral aspect of the
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hemisphereThe central sulcus is the only sulcus that
indents the superior medial border
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-10
Main sulci (Cont'd)
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Lateral sulcus
Deep cleft on the inferior and lateral
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surfaces of the cerebral hemisphereIt consists of a short stem and three rami
- Anterior horizontal , anterior
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ascending and posterior
11
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Main sulci (Cont'd)Parieto-occipital sulcus:
Begins on the superior medial border of
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the hemisphere, about 5 cm anterior to
the occipital pole
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It passes downward and anteriorly on themedial surface to meet the calcarine
sulcus
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Main sulci (Cont'd)
Calcarine Sulcus- Medial surface
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Insula/Island Of Reil
? portion of the cerebral cortex
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folded deep within the lateralsulcus.
? Play a role in consciousness and
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emotions
? The cortical area overlying the
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insula toward the lateral surface ofthe brain is the operculum
(meaning lid).
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? The opercula are formed from
parts of the enclosing frontal,
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temporal, and parietal lobes.? Insulaa is surrounded by circular
sulcus ( arrow !! )
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Superior surface
of temporal
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operculumpresents
anterior and
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posterior
transverse
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temporal gyriOther Sulci and Gyri
Superolateral su12rface
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Frontal lobe ? anterior to central sulcusand superior to lateral sulcus
Superolateral surface of frontal lobe is
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divided by three sulci into four gyri
Precentral sulcus and gyrus
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Superior and inferior frontal sulciSuperior, middle and inferior frontal gyri
Anterior and ascending rami of lateral
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sulcus divide inferior frontal gyrus into
PARS ORBITALIS, PARS TRIANGULARIS PARS
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OPERCULARIS13
15
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Superolateral surfaceParietal lobe ? POST
CENTRAL SULCUS AND
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GYRUS
o INTRAPARIETAL SULCUS
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AND SUPERIOR ANDINFERIOR PARIETAL LOBULE
Lateral
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sulcus
Superolateral surface
o PARIETAL LOBE-Few sulci extend into inferior
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parietal lobule and divided into
o SUPRAMARGINAL GYRUS AROUND LATERAL
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SULCUSo ANGULAR GYRUS AROUND SUPERIOR
TEMPORAL SULCUS
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o ARCUS TEMPORO-OCCIPITALIS AROUND
INFERIOR TEMPORAL SULCUS
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14Superolateral surface
Temporal lobe ? inferior to lateral sulcus
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Two sulci ? SUPERIOR AND INFERIOR
SULCUS
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Three gyri- SUPERIOR, MIDDLE ANDINFERIOR TEMPORAL GYRI
Superior surface of temporal operculum
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(Superior temporal gyrus)presents anterior andposterior transverse temporal gyri. Anterior
gyrus forming primary auditory area, also called
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HESCHL'S GYRUSSuperolateral surface
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Occipital lobe ? small area behind theparieto-occipital sulcus
LATERAL OCCIPITAL SULCUS
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LUNATE SULCUSTRANSVERSE OCCIPITAL SULCUS
MEDIAL SURFACE
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CINGULATE SULCUS AND CINGULATE GYRUS
CALLOSAL SULCUS
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PARACENTRAL LOBULE(CORTICAL CENTRE OFMICTURATION AND DEFECATION) AND MEDIAL FRONTAL
GYRUS
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CALCARINE SULCUS AND PARIETO-OCCIPITAL SULCUS
SUPRASPLENIAL SULCUS IN PRECUNEUS
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INFERIOR SURFACE
ORBITAL SURFACE- OLFACTORY SULCUS, GYRUS RECTUS
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ORBITAL SULCUS AND ORBITAL GYRITENTORIAL SURFACE- MEDIAL COLLATERAL SULCUS AND LATERAL OCCIPITO-TEMPORAL
SULCUS
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LINGUAL GYRUS ? BETWEEN COLLATERAL SULCUS AND CALCARINE SULCUS
LINGUAL GYRUS ANTERIORLY CONTINUE WITH PARAHIPPOCAMPAL GYRUS WHOSE
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ANTERIOR END HOOK LIKE LIMITED BY RHINAL SULCUS- UNCUSMEDIAL AND LATERAL OCCIPITO- TEMPORAL GYRUS
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BLOOD SUPPLY- SUPEROLATERAL
SURFACE
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MIDDLE CEREBRAL ARTERY EXCEPT
STRIP ALONG SUPEROMEDIAL BORDER FROM FRONTAL
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POLE TO PARIETO OCCIPITAL SULCUS BY ACAOCCIPITAL LOBE AND INFERIOF TEMPORAL GYRUS
EXCLUDING TEMPORAL POLE BY PCA
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BLOOD SUPPLY- INFERIOR
SURFACE
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ACA- MEDIAL PART OF ORBITAL SURFACEMCA-LATERAL PART OF ORBITAL SURFACE AND
TEMPORAL POLE
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PCA- TENTORIAL SURFACE
BROADMANS AREAS AND
FUNCTIONAL AREAS OF CEREBRAL
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HEMISPHERE
Specific
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Sulci/Fissures:Central Sulcus
Longitudinal
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Fissure
Sylvian/Latera
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l FissureTransverse Fissure
http://www.bioon.com/book/biology/whole/image/1/1
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http://www.dalbsoutss.eq.edu.au/Sheepbrains_Me/human_bra
Frontal Lobe - Cortical Regions
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Primary Motor Cortex/Brodmann,s area 4
Precentral Gyrus ? it cntro
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ls
all voluntary movements of
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the contralateral side of thebody
Site where movements of
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the various parts of the
body are initiated
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Recieves sensory input fro mcerebellum and thalamus
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The body is represented
upside down along the
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precentral gyrusInvestigation (Phineas Gage)
Primary Motor
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Cortex/ Precentral
Gyrus
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Broca's AreaOrbitofrontal
Cortex
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Olfactory Bulb
Regions
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Modified from:secondary motor area/6,8,44 and 45
Precentral gyrus,sup,middle,inf frontal gyri
It programs the activity of the PMA
Stronger stimulation is required to produce
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the same degree of movement
Broca's Area ?44,45
Inf.frontal gyrus
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Brings about the formation of words.Located on Left Frontal Lobe
Broca's Aphasia ? Results in the ability to
comprehend speech, but the decreased
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motor ability (or inability) to speak and
form words
Frontal eye field 8,
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Middle frontal gyrusVoluntary eye movements towards
opposite side and the
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accomodation pathwayalso controls eyelid movements
Prefrontal cortex9,10,11,12
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Concerned with the makeup of theindividual,s personality
Head rotation area
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Parietal Lobe - Cortical Regions
Primary sensorymotor Cortex
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1,2,3(Postcentral Gyrus) ? Site involved withprocessing of tactile and proprioceptive
information.
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?Somatosensory Association Cortex -5,7 sup
parietal assists with the integration and
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interpretation of sensations.?Primary Gustatory Cortex 43
?Inferior part of the post central gyrus? Primary site
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involved with the interpretation of the sensation of
Taste.
Primary
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Somatosensory
Cortex/ Postcentral
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GyrusSomatosensory
Association Cortex
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Primary Gustatory
Cortex
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Modified from:http://www.bioon.com/book/biology/whole/image/1/1-8.tif.jpg
Regions
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Occipital Lobe ? Cortical
Regions
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Primary Visual Cortex ? This is the primary area ofthe brain responsible for Vision
?Visual Association Area ? Interprets
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information acquired through the
primary visual cortex.
Primary Visual
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Cortex
Visual Association
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AreaModified from:
http://www.bioon.com/book/biology/whole/image/1/1-8.tif.jpg
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Regions
Temporal Lobe ? Cortical
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RegionsPrimary Auditory Cortex ?41,42 mostly
hidden in the lateral sulcus
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Responsible for hearing
Its anterior part recieves low freq sounds
Post part ?high freq sounds
Sec. Auditory Cortex 22
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Interpretation of soundsTemporal Lobe ? Cortical
Regions
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?Primary Olfactory Cortex ? sense of smel(Not visible on the superficial cortex)
?Wernicke's Area superior and middle
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temporal gyri
?Understanding of speech
- Wernicke's Aphasia ? Words and sentences are
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not clearly understood, and sentence formation
may be inhibited.
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Primary AuditoryCortex
Wernike's Area
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Primary Olfactory
Cortex (Deep)
Conducted from Olfactory
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Bulb
Modified from:
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Regionshttp://www.bioon.com/book/biology/whole/image/1/1-8.tif.jpg
dominant hemisphere
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95-leftBroca
90% right handed
BLOOD SUPPLY
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Anterior and middle cerebral artery(internal carotid artery)
Posterior cerebral artery (basilar artery)
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Physiological information about brain
? Left hemisphere is dominant in Which hemisphere
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90% of the right handed and 64%is dominant ?!
of the left handed
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? Righ hemisphere is dominant in
10% of righ handed and 20% of
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left handed? In the remaining 16% of left
handed both hemispheres are
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dominant .
? Speech areas in brain usual y in
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the dominant hemisphere !! ( OFCLINICAL IMPORTANT )
Brodmann areas
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Motor areas of cortex? 1- primary motor area :-
- MSI area ( precentral gyrus )
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MSI
- MSI area ( Anterior part of
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MSIparacentral lobule )
? 2- secondary motor area
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? Posterior parts of frontal
gyri extending medial y
Primary motor area
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? Broadmann area 4? The area Msl is where movements
of the various parts of the body
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are initiated,
MSI
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? Afferent :- receives its main inputsMSI
from
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the
cerebel um
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andthalamus.
? Efferent :- the corticonuclear and
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corticospinal (pyramidal) tracts.
? MSI area receives many fibres
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from the basal nuclei and isconcerned
with
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postural
mechanisms, but this area is not
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yet clearly understood.Motor homunculus
? the body is represented upside
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down along this cortex, although
the face itself is represented the
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right way up.? The face lies lowest, then the
hand (a very large area), then arm,
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trunk and leg.
? The leg and perineum areas
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overlap the superior border andextend down on the medial
surface of the hemisphere
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? Blood supply :-
? 1- middle cerebral artery
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? 2- anterior cerebral a. ( leg area )Primary motor area
? Lesions to this area produce
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contralateral paralysis !!? Organs that supplied bilateral y
are the less affected ...
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? CNs are supplied bilateral y ?!!
Secondary motor area
? Or supplementary motor area
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? Broadmann are 6? Location :- Posterior parts of
frontal gyri extending medial y
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? The function of the secondarymotor area:
? 1- To store programs of motor
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activity
resulted
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frompast
experience
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? 2-
Controls
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sequenceof
movements
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? 3- Controls spatial & postural
orientation movements.
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? 4- Controls bimanual movements.? Blood supply: Middle & anterior
cerebral arteries
secondary motor area
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? Lesions :-? Apraxia (inability to execute learned purposeful movements despite
having the desire and the physical capacity to perform them).
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? There is no or little loss of strength
Boca's area
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? The motor (anterior) speech area(of Broca, areas 44 and 45) is
usual y situated in the inferior
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frontal gyrus on the left side (in
right-handed and in most left-
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handed people), below and infront of the face area and centred
on the pars triangularis between
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the anterior and ascending rami of
the lateral fissure.
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? Damage to it produces motoraphasia -- difficulty in finding the
right words, but not paralysis of
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laryngeal musculature.
? Blood supply :-
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? Middle cerebral a.Wernicke's area
? The posterior speech area (of
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Wernicke) is in the posterior parts ofthe superior and middle temporal gyri
and extends into the lower part of the
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parietal lobe.
- It is connected to the Broca's, visual &
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auditory cortex? Function:
? To understand the written and spoken
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language
? Its integrity is necessary for the
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understanding of speech.? Lesion ... Receptive dysphasia; the
patient responds by intact, but
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irrelevant speech!
? Blood supply:
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? Middle cerebral arteryPrefrontal cortex
? The prefrontal cortex is an
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extensive area that lies anterior tothe precentral
? The prefrontal area is concerned
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with
1. the makeup of the individual's
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personality.2. regulator of the person's depth of
feeling.
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3. It also exerts its influence in
determining the initiative and
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judgment of an individual.Prefrontal cortex
? Lesions :-
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? It is now general y agreed thatdestruction of the prefrontal
? region does not produce any
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marked loss of intelligence
? Tumour or traumatic destruction
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of the prefrontal cortex result inthe person's losing initiative and
judgment.
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? Emotional changes that occur
include a tendency to euphoria.
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? The patient no longer conforms tothe accepted mode of social
behavior and becomes careless of
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dress and appearance.
? Bipolar disorders
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? SchizophreniaSensory areas
? 1- Primary somatosensory area
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- The postcentral gyrus1
- Posterior part of l p
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o a
b r
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u alcee ntral
2
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- Recieves primary from thalamus
- Sensations from the oral region,
pharynx, larynx & perineum are
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received bilateral y
? 2- Secondary ( or association )
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somatosensory area.- Occupies the superior parietal
lobule
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Primary sensory area? Sensory homunculus:
? The amount of the cortex for a
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particular part of the bod isrelated
to
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its
functional
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importance&
number
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of
receptors ( not to its size)
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? Blood supply:- Middle cerebral artery
- Anterior cerebral artery (leg area)
Primary sensory area
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? Lesions :-
? Lesions
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ofthe
primary
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somesthetic area of the cortex
result in contralateral sensory
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disturbances, which are mostsevere in the distal parts of the
limbs. Crude painful, tactile,and
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thermal stimuli often return,but
this is believed to be due to the
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function of the thalamus.? The patient remains unable to
judge
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? degrees of warmth, unable to
localize tactile stimuli accurately,
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and unable to judge weights ofobjects.
? Loss of muscle tone may also be a
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symptom of lesions of the sensory
cortex.
Secondary somatosensory area
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? Function:- Receive different sensory
modalities & relate them to past
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experience. e.g; object recognitionwithout vision.
- Lesions = asterognosis !!
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- Inable to identify things withoutsee them ...
Primary visual cortex
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? Broadmann area 17? Functions:
- Receives fibers from the opposite
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field of vision- It also excludes & modulates
unwanted images!
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? Blood supply:
- Posterior cerebral artery
? Lesions :-
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? Crossed homonymous hemianopiaSecondary visual cortex
? Brodmann area 18,19
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? Surrounded by the primary visualcortex ...
? Functions to relate the visual
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information to past experiences
? Lesions produce ... Visual agnosia;
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loss of ability to recognize objectsseen in the opposite field of vision
WHY don't we see everything upside-down?
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? -Brain makes images 'easier' to see by:? 1- Combining the two images of the two eyes (in corpus cal osum).
? 2- Make images right-side-up (in the visual cortex).
? It does this because your brain is so USED to see things upside-down that
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it eventual y adjusts to it (it's easier to flip the image than to try using
hands and legs with an upside-down world)
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? For the first days, babies see everything upside-down!Primary auditory area
? Broadmann area 41,42
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? In the inferior wal of lateral sulcus? Afferent: Principal y from the
medial geniculate body
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? Blood supply:
- Middle cerebral artery
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- Lesionsproduce ...
Partial
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deafness in both ears with
inability to locate sound.
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- The greater loss being in theopposite ear
- (cochlear nuclei send 2nd order to
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the olivary nucleus & nuclei of
trapezoid body bilateral y)
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Auditory pathway? Explaning why greter loss of
inability to hear on the
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opposite site !!!
? Cochlear n. send fibers more
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to the other side than thesame side ...
Secondary auditory area
? Broadmann area 22
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? Lies posterior to the primaryauditory area
? Function:
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- To interpret sounds and associatethe auditory input with other
sensory information.
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? Blood supply:
? Middle cerebral artery
? Lesions : auditory agnosia !!
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The dominant angular gyrus
? This part is often considered a
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part of the Wernicke area? Lesion here results in inability to
read (alexia) or write (agraphia).
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AphasiaSensory aphasia
Alexia
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Agraphia
Motor aphasia
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A lesion resulting in a nonfluent expressiveaphasia would most likely be found in the
(A) temporal lobe
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(B) parietal lobe
(C) frontal lobe
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(D) occipital lobeAlexia without agraphia and aphasia would
most likely result from occlusion of the
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(A) left anterior cerebral artery(B) right anterior cerebral artery
(C) left middle cerebral artery
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(D) left posterior cerebral artery
(E) right posterior cerebral artery
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A patient is asked to bisect a horizontal linethrough the middle, to draw the face of a clock,
and to copy a cross. The patient bisected the
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horizontal line to the left of the midline,
placed all of the numerals of the clock on the
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right side, and did not complete the cross onthe left side. The most likely lesion site for this
deficit is the
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(A) left frontal lobe
(B) right parietal lobe
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(C) left parietal lobe(D) right temporal lobe
(E) left occipital lobe
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Arterial supply to Brain? Tissue of the brain ( paranchyme )
al is supplied by two sources ...
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? 1- branches of internal carotid1
ACA
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MCA
artery
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? 2- branched of basilar artery2
ECA
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ICA
PCA
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Basialr a.CCA
Vertebral a.
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Vertebral a.
aorta
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Subcalvain a.Subcalvain a.
Branches of the vertebral a.
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1. Posterior
inferior
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cerebel ar a.2. Anterior spinal a.
2
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1
Branches of the basilar a.
1. Anterior inferior cerebel ar a.
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2. Superior cerebel ar a.3. Posterior cerebral a.
32
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1Blood supply to Brain
Anterior cerebral artery
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? leaves the internal carotid arteryand passes forwards above the
optic nerve
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? It is connected to its fellow of the
opposite side by the anterior
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communicating artery. It isdistributed to the orbital surface of
the frontal lobe and to the whole
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of the medial surface of the
hemisphere above the corpus
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cal osum as far back as the parieto-occipital sulcus
Anterior cerebral artery
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? The motor and sensory areas for the opposite leg, foot and perineum,
including the micturition and defecation centres, lie in its territory.
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? Because of the anastomosis via the anterior communicating artery, it isusual y possible for one anterior cerebral to be supplied with blood from
the contralateral internal carotid.
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Anterior cerebral a. syndrome1. Hemiparesis or hemiplegia contralateral y, involving primarily the lower
limbs and pelvic floor musculature
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2. Sensory deficits contralateral y, involving primarily the leg and perineum3. Apraxia (due to branches to the supplementary motor area and corpus
cal osum)
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4. Disconnection syndrome (due to cal osal branches)5. Anosmia (due to branches of the olfactory bulb and olfactory tract)
6. Urinary incontinence
7. Grasp reflex and or sucking reflex contralateral y (if circle of Wil is
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compromised)Middle cerebral artery
? The middle cerebral artery is
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the largest and most directbranch of the internal carotid
and therefore most subject to
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embolism.
? It passes deep into the lateral
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sulcus to supply the cortex ofthe insula and overlying
opercula.
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? It reaches the lateral surface of
the hemisphere
Middle cerebral artery
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? by continuing in the lateral
sulcus, from which its branches
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emerge and ramify over an areathat fal s short of the borders of
the lateral surface by one gyrus
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or its equivalent breadth.
?
? In its area of cortical
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distribution lie the motor and
sensory areas for the opposite
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half of the body, excluding leg,foot and perineum (which are in
anterior cerebral territory), and
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the auditory and speech areas.
Middle cerebral a. syndrome
1. Hemiparesis or hemiplegia of the lower half of the contralateral face
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2. Hemiparesis or hemiplegia of the contralateral upper and lowerextremities
3. Sensory loss of the contralateral face, arm and leg
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4. Ataxia of contralateral extremities5. Speech impairments/aphasia: Broca's area, Wernicke's or Global aphasia
as a result of a dominant hemisphere lesion (usual y the left brain)
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6. Perceptual deficits: hemispatial neglect, anosognosia, apraxia, andspatial disorganization as a result of a non-dominant hemisphere lesion
(usual y the right brain)
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7. Visual disorders: d?viation conjugu?e, a gaze preference towards the side
of the lesion; contralateral homonymous hemianopsia
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Note: *faciobrachial deficits greater than that of the lower limbPosterior cerebral artery
? The posterior cerebral artery
curls back around the cerebral
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peduncle supplying it and the
optic tract, and passes back
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above the tentorium to supplythe inferomedial surface of the
temporal and occipital lobes
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? Its territory meets that of the
anterior cerebral artery at the
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parieto-occipital sulcus.Its
branches extend around the
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borders of the brain to supply
the inferior temporal gyrus and
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a corresponding strip of cortexon the lateral surface of the
occipital lobe. .
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Posterior cerebral artery
? The visual area for the
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opposite field of vision lieswhol y within its territory,
but the middle cerebral
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branches can sometimes
extend sufficiently far back
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on the occipital lobe tosupply the macular part of
the visual area .
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? Thus the macular field of
vision may be spared when
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the rest of the visual area isdestroyed by a posterior
cerebral thrombosis.
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Posterior cerebral a. syndrome1. Visual disorder : Contralateral homonymous hemianopsia & cortical
blindness with bilateral involvement of the occipital lobe branches
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2. visual agnosia3. dyslexia, Anomic aphasia, color naming and discrimination problems
4. memory defect
5. involuntary movements: chorea, intention tremor, hemibal ismus
6. contralateral hemiplegia
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7. Weber's syndrome: occulomotor nerve palsy8. B?lint's syndrome: loss of voluntary eye movements optic ataxia,
asimultagnosia (inability to understand visual objects).
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Circle of wil is? 1, Internal carotid artery.
? 2, Posterior cerebral
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artery.
8
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? 3, Anterior cerebralartery.
? 4, Anterior cerebral
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artery.
? 5, Middle cerebral artery.
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? 6, Basilar artery.? 7, Vertebral artery.
? 8, anterior
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communicating artery .--- Content provided by FirstRanker.com ---