Download MBBS Biochemistry PPT 17 Basic Genetics Lecture Notes

Download MBBS (Bachelor of Medicine, Bachelor of Surgery) 1st year (First Year) Biochemistry ppt lectures Topic 17 Basic Genetics Notes. - biochemistry notes pdf, biochemistry mbbs 1st year notes pdf, biochemistry mbbs notes pdf, biochemistry lecture notes, paramedical biochemistry notes, medical biochemistry pdf, biochemistry lecture notes 2022 ppt, biochemistry pdf.

What is Karyotype

a picture of arranged chromosomes.

The picture is created by photographing the cell during mitosis

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What can be learnt from making a karyotype?

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Monosomy (Turner syndrome)

Trisomy 21 Down syndrome

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Klinefelter syndrome

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Chromatin/Chromosome/Chromatid

(Euchromatin and Heterochromatin)

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Chromatin :

Euchromatin and Heterochromatin

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Gene/ Allele/ Locus

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Gene:Portion of a chromosome that

serves as the basic unit of heredity

Allele:Pair of genes that code for

polypeptide s that express the

same physical trait are called alleles

Locus:Specific position of a gene

on chromosome

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3p22.1

Cytogenetic location

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Genotype:

Combination of alleles of a gene carried by an organism

Phenotype:

Expression of alleles of a gene carried by an organism

Homozygous:

Having two similar alleles

Homozygous dominant: Having two copies of the

same dominant allele

Homozygous recessive: Having two copies of the

same recessive allele

Heterozygous:

Having two different alleles, the dominant allele is expressed

Carrier:Heterozygous carrier of a recessive disease causing allele16

Cell Division :Mitosis and Meiosis

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Nondisjunction

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Aneuploidy and Polyploidy

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Aneuploidy

2n+1= Trisomy

2n-1= Monosomy

2n-2= Nullisomy

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The eukaryotic cell cycle

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