QP. CODE: MB2019105
KALOJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCES
WARANGAL, TELANGANA STATE-506 002
MBBS FIRST YEAR EXAMINATIONS: AUGUST, 2024
PHYSIOLOGY PAPER-I
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Time: 3 Hours Max Marks: 100
Note: Answer all questions.
Give Diagrammatic representation whenever necessary
Multiple Choice Questions: 10x1=10
- Cortical nephrons differ from juxtamedullary nephrons in all except
- Glomeruli are located in the renal cortex
- Have short loop of Henle
- Henle loop have rich vascular supply in the form of vasa recta
- Nephrons play a major role in excretion of waste products
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- Simple diffusion and facilitated diffusion share which of the following characteristics?
- Can be blocked by specific inhibitors
- Do not require adenosine triphosphate (ATP)
- Require transport protein
- Saturation kinetics
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- A 60-year-old man's ECG shows that he has an R-R interval of 0.55 sec. Which of the following best explains his condition?
- He has fever
- He has a normal heart rate at rest
- He has excess parasympathetic stimulation of the S-A node
- He is a trained athlete at rest
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- Laminar flow in small airways is due to?
- Small diameter
- Small area of cross section
- Low velocity of flow
- Reynolds's number more than 2000
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- S.A. node acts as a pacemaker of the heart because?
- Is capable of generating impulses spontaneously
- Has rich sympathetic innervations
- Has poor cholinergic innervations
- Generates impulses at the highest rate
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- Pulmonary surfactant is secreted by
- Type I Pneumocytes
- Type II Pneumocytes
- Clara cells
- Bronchial epithelial cells
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- Iron is actively absorbed in:
- Stomach
- Duodenum and proximal jejunum
- Large intestine
- Ileum
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- Bile acids are synthesized from
- Cholesterol
- Amino acids
- Bilirubin
- Protein
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- Liver synthesizes all, EXCEPT
- C3 complement component
- Haptoglobin
- Fibrinogen
- Immunoglobulin
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- Osmotic pressure of a solution is related to the
- Number of particles dissolved in the solution
- Size and type of the particle
- Chemical composition of the solution
- Number of equivalents of the electrolyte in the solution
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Essay/ Long Answer Questions: 2x15=30
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- Describe in detail the genesis of respiration and explain the chemical factors affecting the respiratory centres
- 25 year old female comes to clinic seeking for physical fitness certificate. All investigations were done including renal function tests. The details are below:
Blood Urea concentration - 0.15mg/ml.
Urinary urea concentration-7.5mg/ml, Urine flow-1ml/min- Calculate the urea clearance and comment on the value
- What are the other substances that can be used to measure renal clearance
- Define GFR (Glomerular Filtration Rate). Give its normal value.
- Describe the factors affecting GFR.
- How is GFR regulated.
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Short Answer Questions: 7x6=42
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- Define and classify immunity. Briefly explain CMI
- Mechanism of secretion of HCl in stomach.
- Describe major and minor cross matching. Mention the immediate complications of mismatch blood transfusion.
- Mention the different types of intercellular junctions with examples. Briefly explain the structure and importance of gap junctions in cardiac muscle.
- Describe and discuss the commitment to lifelong learning as an important part of physician growth
- Explain the conducting system of heart with labelled diagram. What is the importance of AV nodal delay.
- Define Homeostasis and describe about various feedback mechanisms.
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Very Short Answer Questions: 6x3=18
- Give the morphological classification of anaemia with an example for each
- List the functions of bile.
- List functions of plasma proteins
- Define apoptosis. Mention its physiological significance
- Define uniport, symport and antiport with examples.
- Poiseuille's law and its importance.
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