QP. CODE: MB2019106
KALOJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCES
WARANGAL, TELANGANA STATE-506 002
MBBS FIRST YEAR SUPPLEMENTARY EXAMINATIONS: NOVEMBER, 2024
PHYSIOLOGY PAPER-II
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Time: 3 Hours
Max Marks: 100
Note: Answer all questions.
Give Diagrammatic representation whenever necessary
Multiple Choice Questions:
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10x1=10
- Which of the following describes a connection between components of the basal ganglia?
- The subthalamic nucleus releases glutamate to excite the globus pallidus, internal segment
- The substantia nigra pars reticulata releases Dopamine to inhibit the striatum
- The substantia nigra pars compacta releases Dopamine to excite the Globus pallidus, external Segment
- The striatum releases acetylcholine to excite the substantia nigra para reticulata
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- Tetany features include all of the following except
- Neuromuscular hyperexcitability
- Carpopedal spasm
- Trousseau's sign
- Clotting defects
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- Calcium metabolism is mainly dependent on
- Calcitonin
- Parathormone
- Thyroxine
- Growth Hormone
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- Oogenesis begins:
- From approx. 10th week of foetal life
- At term
- After birth
- At puberty
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- First synapse of fibers conducting pain takes place at the level of
- Medulla to nucleus cuncatus
- Grey matter of dorsal horn of spinal cord
- Medulla in Nucleus Gracilis
- Thalamus in posterior ventricular musclues
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- Feed forward inhibition:
- Helps to limit the duration of excitation of Purkinje cells produce by any given afferent impulses
- Refers to excitation granule cell is rapidly stopped by negative feedback loop
- Determines inhibitory Purkinje fiber discharge
- regulates excitatory mossy fiber discharge
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- Satiety centre in in hypothalamus mus is regulated by:
- Gastric dilatation
- Blood glucose levels
- Blood insulin levels
- Fatty acids
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- Olfactory receptors are:
- Sensitive to physical stimuli
- Rapidly replaced
- Slowly adapting
- Bipolar neurons
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- A patient complaining of muscle weakness was given neostigmine injection, which improves his muscle strength. The Neostigmine acts by
- Blocking the action of acetylcholine
- Interfering with action of amine oxidase
- Interfering with the action of acetylcholine esterase
- Interfering with the action of carbonic anhydrase
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- Which of the following is NOT a characteristic of an action potential
- Refractory period
- Conductivity
- Accommodation
- Graded response to increasing strength of stimuli
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Essay/ Long Answer Questions:
2x15=30
- A 48-years old female visits, doctor with complaints of weakness, weight gain and feeling of excessive cold. On investigations, her TSH was high and T3, T4 were low.
- Identify the condition.
- Describe in detail the biosynthesis of thyroid hormone Enumerate the functions of the thyroid hormone in different organ systems.
- List the conditions caused due to the alterations in serum thyroid hormone levels.
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(2+5+5+3)
- A male aged 50 years came with progressive loss of vision. On examination, he had loss of vision of temporal quadrants of both eyes.
- Identify the condition and where is the most probable site of lesion.
- Trace the visual pathway.
- Describe the effects of lesion at various levels
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(3+6+6)
Short Answer Questions:
7x6=42
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- Describe the steps involved in the transmission of impulses across the neuromuscular junction. Discuss the role of neuromuscular blocking agents.
- Mention the stages of Spermatogenesis and describe the role of hormones and factors influencing Spermatogenesis.
- Enumerate the Functions of thalamus.
- Describe the tests for ovulation.
- Discuss the role of skin in temperature regulation.
- Describe the causes and manifestations of Cushing's Syndrome.
- Describe the mechanisms involved in pain modulation.
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Very Short Answer Questions:
6x3 =18
- Renshaw cell inhibition
- Receptor potential.
- Describe the rights and responsibilities of patients.
- List the contraceptive methods in females. Briefly explain the mechanism of action of intrauterine contraceptive devices.
- Describe Sarco-tubular system in skeletal muscle
- Cochlear microphonic potentials
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