Download KNRUHS 2nd Year MBBS 2024 February MB2019112 Pharmacology Paper II Question Paper

Time: 3 Hours                                                                           Max Marks: 100

Note: Answer all questions.
Give Diagrammatic representation wherever necessary.

Multiple Choice Questions:

1. The most common adverse reaction to insulin is:
   1. Hypoglycaemia

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   2. Lipodystrophy
   3. Urticaria
   4. Angioedema
2. Absorption of oral iron preparations can be facilitated by co-administering:
   1. Antacids

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   2. Tetracyclines
   3. Phosphates
   4. Ascorbic acid.
3. Indicate the enzyme inhibited by fluoroquinolones:
   1. Dihydro folate reductase

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   2. Topoisomerase II
   3. Topoisomerase III
   4. Topoisomerase IV
4. Optic neuritis is caused by
   1. INH

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   2. Streptomycin
   3. Rifampicin
   4. Ethambutol
5. Which of the following is not used in the management of hyperprolactinemia
   1. bromocriptine.

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   2. cabergoline
   3. pergolide
   4. Lanreotide
6. The product Dettol consists of which antiseptic
   1. Cresol

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   2. Lysol
   3. Chloroxylenol
   4. Chlorhexidine
7. All are aminoglycosides except
   1. Neomycin

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   2. Azithromycin
   3. streptomycin
   4. Amikacin
8. Sulfadoxine-pyrimethamine combination is used as clinical curative but is not recommended in
   1. Megaloblastic anaemia

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   2. Risk of severe dermatological reactions to sulfadoxine
   3. Need for daily administration of the drug
   4. Slow schizonticidal action of the drug
9. PUVA therapy is used in:
   1. Psoriasis

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   2. Lichen planus
   3. Freckles
   4. Melasma
10. All vaccines are indicated at 6 weeks except:
    1. BCG

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    2. DPT
    3. OPV
    4. Hepatitis B

Essay/Long Answer Questions: 2X15=30

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11. Enumerate Oral Contraceptive Pills. Explain the actions and adverse effects of OCPs. Add a note on emergency contraceptive pills. (6+3+3+3)
12. Classify Semisynthetic Penicillins. Describe the mechanism of action, antimicrobial Spectrum, adverse effects, and uses of Amoxicillin. (4+3+3+2+3)

Short Answer Questions: 7 X 6 = 42

13. Local Haemostatics.
14. Loop Diuretics.

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15. Drug therapy of Chloroquine Resistant Malaria.
16. Toxicity of Anticancer drugs and methods to Ameliorate the toxicity.
17. Low molecular weight Heparins.
18. Angiotensin converting Enzyme Inhibitors.
19. Plasma Expanders.

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Very Short Answer Questions: 6 X 3 = 18

20. Mention three drugs used for Scabies.
21. Mention three drugs used in Hypertensive emergency crisis.
22. Enlist three long term side effects of Glucocorticoids.
23. Tamoxifen.

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24. Why tetracycline is contraindicated during Pregnancy.
25. Adverse effects of Rifampicin.

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