PTU B-Pharma 7th Semester May 2019 71753 PHARMACEUTICAL BIOTECHNOLOGY Question Paper

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Roll No.

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Total No. of Questions : 10

Total No. of Pages : 02

B.Pharma (2011 to 2016) (Sem.-7)

PHARMACEUTICAL BIOTECHNOLOGY

Subject Code : BPHM-701

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M.Code: 71753

Time: 3 Hrs.

Max. Marks : 80

INSTRUCTION TO CANDIDATES :

1. SECTION-A is COMPULSORY consisting of FIFTEEN questions carrying TWO marks each.

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2. SECTION-B contains FIVE questions carrying FIVE marks each and students have to attempt ANY FOUR questions.
3. SECTION-C contains FOUR questions carrying TEN marks each and students have to attempt ANY THREE questions.

SECTION-A

1. Define with examples :

1. Biotechnology

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2. Fermenter
3. Protease
4. Enzymes
5. Culture
6. Antigen

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7. Cloning
8. Transduction
9. Biotransformation
10. Antibodies

Distinguish between :

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1. Batch culture and continuous culture
2. Active and passive immunity
3. Toxin and Toxoid
4. Vaccine and antibiotics
5. Penicillins and tetracyclines

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SECTION-B

2. Explain the principles of immune system.

3. How Humulin is prepared by genetic recombination?

4. Explain the factors influencing rate of mutation.

5. Enumerate designing of biotransformation processes.

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6. Highlight the techniques of immobilization of enzymes.

7. How bacteria is immobilized? Explain streptokinase.

8. Explain the isolation of streptomycins by fermentation technology.

9. Give construction and working including controlling of parameters of a fermenter.

10. Write short notes on :

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1. Hepatitis B vaccine
2. Vitamin B12

NOTE : Disclosure of Identity by writing Mobile No. or Making of passing request on any page of Answer Sheet will lead to UMC against the Student.