--- Content provided by FirstRanker.com ---Time: Three Hours
Max. Marks: 70 Marks
PHARMACEUTICAL ORGANIC CHEMISTRY ? I (RS - 4)
Q.P. CODE: 2628
Draw neat, labeled diagrams wherever necessary
LONG ESSAYS (Answer any Two)
2 x 10 = 20 Marks
1.
2.
a) Define electrophilic aromatic substitution reaction. Classify substituent groups with examples.
3.
What are elimination reactions? Discuss the kinetics, mechanism, orientation and reactivity of E1
SHORT ESSAYS (Answer any Six)
6 x 5 = 30 Marks
4.
What are cycloalkanes? Write any three methods of preparation.
Explain dehydration of alcohol with mechanism.
6.
Discuss the stability of conjugated dienes with examples.
7.
8.
Write the conversion of acid to acid chloride, amide and ester.
9.
Explain the mechanism of Markovnikov's rule with suitable example.
11. Write the Haworth synthesis of naphthalene.
SHORT ANSWERS
10 x 2 = 20 Marks
12. Write the structure of a) 2-bromo 3-methyl hexane b) Methanol
13. Define and classify hydrogen bond with example.
14. Write any one method for formation of free radicals with example.
15. Elimination vs Substitution reactions.
17. Why aliphatic amines are more basic than aromatic amines?
18. What is Sandmeyer's reaction?
19. Write the effects of substitution on acidity of Phenols.
20. Write the structure and IUPAC name of a) Acetone b) Diethyl ether
*****
Max. Marks: 70 Marks
--- Content provided by FirstRanker.com ---
PHARMACEUTICAL ORGANIC CHEMISTRY ? I (RS - 4)
Q.P. CODE: 2628
--- Content provided by FirstRanker.com ---
Your answers should be specific to the questions askedDraw neat, labeled diagrams wherever necessary
LONG ESSAYS (Answer any Two)
--- Content provided by FirstRanker.com ---
2 x 10 = 20 Marks
1.
--- Content provided by FirstRanker.com ---
Explain kinetics, mechanism, stereochemistry and reactivity of SN2 reaction.2.
a) Define electrophilic aromatic substitution reaction. Classify substituent groups with examples.
--- Content provided by FirstRanker.com ---
b) Explain the mechanism of Friedel-Craft's alkylation with their limitations.3.
What are elimination reactions? Discuss the kinetics, mechanism, orientation and reactivity of E1
--- Content provided by FirstRanker.com ---
reaction.SHORT ESSAYS (Answer any Six)
6 x 5 = 30 Marks
--- Content provided by FirstRanker.com ---
4.
What are cycloalkanes? Write any three methods of preparation.
--- Content provided by FirstRanker.com ---
5.Explain dehydration of alcohol with mechanism.
6.
--- Content provided by FirstRanker.com ---
Discuss the stability of conjugated dienes with examples.
7.
--- Content provided by FirstRanker.com ---
Explain Cannizzaro condensation with mechanism.8.
Write the conversion of acid to acid chloride, amide and ester.
--- Content provided by FirstRanker.com ---
9.
Explain the mechanism of Markovnikov's rule with suitable example.
--- Content provided by FirstRanker.com ---
10. What is Aldol condensation? Discuss the mechanism involved.11. Write the Haworth synthesis of naphthalene.
SHORT ANSWERS
10 x 2 = 20 Marks
--- Content provided by FirstRanker.com ---
12. Write the structure of a) 2-bromo 3-methyl hexane b) Methanol
13. Define and classify hydrogen bond with example.
14. Write any one method for formation of free radicals with example.
15. Elimination vs Substitution reactions.
--- Content provided by FirstRanker.com ---
16. What is Crossed Aldol condensation reaction? Give example.17. Why aliphatic amines are more basic than aromatic amines?
18. What is Sandmeyer's reaction?
19. Write the effects of substitution on acidity of Phenols.
20. Write the structure and IUPAC name of a) Acetone b) Diethyl ether
--- Content provided by FirstRanker.com ---
21. Define and classify free radicals with examples.*****