Download RGUHS B.Pharm 2018 January 2nd Year 2607 Pharmaceutical Microbiology And Biotechnology Revised Scheme 3 Question Paper

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Time: Three Hours



Max. Marks: 70 Marks

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PHARMACEUTICAL MICROBIOLOGY & BIOTECHNOLOGY

(Revised Scheme 3)

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Q.P. CODE: 2607

Your answers should be specific to the questions asked

Draw neat labeled diagrams wherever necessary

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LONG ESSAYS (Answer any Two)

2 x 10 = 20 Marks

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1.

Explain the different methods of evaluation of bacteriostatic activity of a disinfectant.

2.

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Write the production of Insulin by rDNA technology.

3.

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Discuss the technique and nutritional requirement of animal cell culture.

SHORT ESSAYS (Answer any Six)

6 x 5 = 30 Marks

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4.

What are antigens? Give their classification and characteristics.

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5.

Write a note on sterilization by radiation.

6.

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Explain the steps involved in the extraction of penicillin from fermentation broth.

7.

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Discuss the various non-specific defense mechanisms.

8.

Give the differences between gram positive and gram-negative cell wall.

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9.

How will you perform assay of antibiotics by turbidimertric method.

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10.

Explain in detail principle and applications of Southern blotting.

11.

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Explain different types of media used in cultivation of microorganisms.

SHORT ANSWERS

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10 x 2 = 20 Marks

12.

Viable count of bacteria

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13.

Phagocytosis

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14.

Continuous cell line

15.

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Sanitisation

16.

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D value

17.

Mould and yeast

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18.

Properties of agar

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19.

Koch postulates

20.

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Sugar fermentation test

21.

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Virulence

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