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Code No. 3211
FACULTY OF SCIENCE
B.Sc. V-Semester (CBCS) Examination, November / December 2018
Subject : Biochemistry (Molecular Biology)
Paper—VI—-A (DSE E-1)
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Time : 3 Hours Max. Marks: 60
PART-A(5x3=15 Marks)
(Short Answer Type)
Note : Answer any FIVE of the following questions.
- DNA ligase
- Nucleosomes
- Sigma factor and promoters
- Inhibitors of transcription
- tRNA
- Signal hypothesis
- Catabolite repression
- Rho-independent transcriptional termination
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PART - B (3 x 15 = 45 Marks)
(Essay Answer Type)
Note: Answer ALL questions.
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- (a) How are the leading and lagging strands of DNA synthesized in E.Coli.? Explain.
OR
(b) Give the experimental evidence to prove semi-conservative mode of replication. Write a note on bi-directional model of replication. - (a) Explain in detail about post-transcriptional processing of eukaryotic mRNA.
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(b) Explain the events of initiation and elongation stages of transcription process in prokaryotes. - (a) Give the important features of genetic code and add a note on wobble hypothesis.
OR
(b) Discuss on regulation of tryptophan operon.
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