MBBS DEGREE EXAMINATION - 1st PROF PROFESSIONAL
SUPPLEMENTARY EXAM - MARCH 2024
BIOCHEMISTRY - PAPER - II
SECTION A - Multiple Choice Questions (MCQs)
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PAPER CODE: 2422130003 SET: CNote: Choose one correct answer in the OMR sheet provided. No overwriting
should be done.
Time: 20 Minutes (20 x 1 = 20 MARKS)
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1. The substance that facilitates protein degradation is:a) phylloquinone
b) ubiquitin
c) ubiquinone
d) menaquinone
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2. The primary defect in Xeroderma pigmentosa is:a) Poly ADP ribose polymerase is defective
b) Formation of thymidine dimers
c) Formation of adenine dimmers
d) Exonuclease is defective
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3. Enzymes responsible for respiratory burst:a) Peroxidases
b) Hydroxylases
c) Dehydrogenases
d) NADPH oxidase
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4. Starting material for production of insulin from bacteria is:a) mRNA of lymphocytes
b) Genomic DNA of lymphocytes
c) Genomic DNA of beta cell of pancreas
d) mRNA of beta cells of pancreas
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5. Nitric acid is a signaling molecule produced from:a) cysteine
b) arginine
c) methionine
d) histidine
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6. Amino acids which absorb ultraviolet light are:a) Basic amino acids
b) Aromatic amino acids
c) Acidic amino acids
d) Neutral amino acids
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7. Which of the following is an antiapoptotic gene:a) P53
b) C-myc
c) Bax
d) Bcl-2
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8. Antigen binding site on immunoglobulin is:
a) Variable region
b) Constant region
c) Hinge region
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d) Hypervariable region9. Vitamin required for post-translational modification of coagulants is:
a) Vitamin A
b) Vitamin C
c) Vitamin B6
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d) Vitamin K10. The amyloid protein deposition associated with Alzheimer's disease is
composed of:
a) Alpha helix
b) Beta pleated sheet
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c) Quaternary structured) Tertiary structure
11. One of the nitrogen atoms of urea molecule is provided by:
a) Aspartate
b) Glutamate
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c) Ornithined) Citrulline
12. Thermostability in DNA is contributed mostly by:
a) A=T
b) G=C
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c) Molecular based) Parallel arrangement
13. Glutathione is a tripeptide made up of:
a) Glutamate + methionine + arginine
b) Glutamate + glycine + arginine
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c) Glutamate + alanine + arginined) Glutamate + cysteine + glycine
14. Rate limiting step for the entire process of hepatic bilirubin metabolism:
a) Uptake of bilirubin by liver with albumin
b) Transport of bilirubin
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c) Secretion of conjugated bilirubin into the biled) Conjugation of bilirubin
15. Glutamine in blood acts as:
a) Toxic element
b) NH3 transporter
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c) Abnormal metabolited) Stored energy
16. An amino acid which becomes essential in phenylketonuria is:
a) Tyrosine
b) Phenylalanine
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c) Methionine
d) Tryptophan
17. Which of the following tests is used to detect proteinuria:
a) Fouchet test
b) Heat coagulation and acetic acid test
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c) Benzidine testd) Hay's sulphur test
18. Antibody that can cross placenta to protect fetus:
a) IgG
b) IgA
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c) IgEd) IgM
19. The enzyme deficient in Lesch-Nyhan syndrome is:
a) HGPRTase
b) GLutaminase
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c) Transcarboxylased) GTRT
20. The mutation found in sickle cell anaemia can be classified as:
a) Non-sense mutation
b) Silent mutation
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c) Insertiond) Missense mutation