Download ABVMU MBBS 1st Year 2024 August Biochemistry Paper I MCQs Question Paper

ATAL BIHARI VAJPAYEE MEDICAL UNIVERSITY, LUCKNOW
MBBS DEGREE EXAMINATION - 1st PROF PROFESSIONAL REGULAR
EXAM - AUGUST 2024
BIOCHEMISTRY - PAPER - I
SECTION A - Multiple Choice Questions (MCQs)

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PAPER CODE: 2411130003 SET: B
Note: Choose one correct answer in the OMR sheet provided. No overwriting
should be done.
Time: 20 Minutes (20 x 1 = 20 MARKS)
1. Which lipoprotein is primarily responsible for delivering cholesterol to cells

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for membrane synapses and hormone production?
a) IDL
b) VLDL
c) LDL
d) HDL

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2. The process of converting acetyl-CoA into malonyl-CoA is called:
a) Ketogenesis
b) Lipogenesis
c) Lipolysis
d) Beta-oxidation

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3. All of the following are responsible for cell junction formation except:
a) Selectins
b) Integrins

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c) Cathepsins
d) Cadherins

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4. Tay-Sachs disease is a disorder of which cell organelle:
a) Endoplasmic reticulum
b) Lysosomes
c) Mitochondria
d) Peroxisome

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5. All affect glucose tolerance test except:
a) Hyperthyroidism
b) Vitamin B12 deficiency
c) Acute infections
d) Liver diseases

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6. Which complex of the electron transport chain is also part of the citric acid
cycle?
a) Complex IV
b) Complex III
c) Complex II

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d) Complex I
7. Cytochrome P450 enzymes are most commonly involved in which phase of
xenobiotic metabolism?
a) Phase IV
b) Phase III

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c) Phase II

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d) Phase I
8. Which of the following is a potent inhibitor of Complex I in the electron
transport chain?
a) Dinitrophenol

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b) Oligomycin
c) Rotenone
d) Cyanide
9. During prolonged fasting, the brain primarily relies on which of the following
substrates for energy?

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a) Ketone bodies
b) Fatty acids
c) Amino acids
d) Glucose
10. Glucose and fructose are examples of:

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a) Isomers
b) Enantiomers
c) Anomers
d) Epimers
11. Which of the following organelles is involved in the detoxification of drugs

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and poisons in the liver cells?
a) Golgi apparatus
b) Rough endoplasmic reticulum
c) Smooth endoplasmic reticulum

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d) Lysosomes

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12. Which of the following pairs are enantiomers?
a) D-Glucose and D-Galactose
b) D-Glucose and L-Glucose
c) D-Glucose and D-Mannose
d) -D-Glucose and -D-Glucose

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13. Elevated levels of which enzyme are most indicative of acute pancreatitis?
a) Gamma-glutamyl transferase
b) Alkaline phosphatase
c) Lipase
d) Amylase

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14. In Lineweaver-Burk plots, what do the x-intercept and y-intercept
represent, respectively?
a) -1/Vmax and 1/Km
b) Vmax and -1/Km
c) -1/Km and 1/Vmax

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d) 1/Km and -1/Vmax
15. Which among the following is the most specific test for diagnosing chronic
kidney disease?
a) Urine protein
b) Creatinine clearance

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c) Serum creatinine
d) Blood urea nitrogen (BUN)

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16. Which of the following is recommended as a supplement in iron deficiency
anaemia?

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a) Vitamin C
b) Vitamin B12
c) Vitamin D
d) Vitamin A
17. Which enzyme is responsible for the breakdown of triglycerides in

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lipoproteins into free fatty acids and glycerol?
a) Acetyl-CoA carboxylase
b) Phospholipase
c) Hormone-sensitive lipase
d) Lipoprotein lipase

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18. The major route of excretion for many xenobiotics is:
a) Saliva
b) Urine
c) Sweat
d) Lungs

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19. The inhibition of which enzyme leads to a build-up of lactate in cells under
anaerobic conditions?
a) Pyruvate dehydrogenase
b) Phosphofructokinase
c) Lactate dehydrogenase

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d) Hexokinase

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20. What is the rate-limiting enzyme in cholesterol synthesis?
a) Mevalonate kinase
b) Squalene synthase

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c) HMG-CoA synthase
d) HMG-CoA reductase
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