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Download VNSGU MBBS 2106000102010101 Pathology Paper I February2024 Question Paper

We uploaded VNSGU (Veer Narmad South Gujarat University or South Gujarat University) MBBS ?(Bachelor of Medicine, Bachelor of Surgery) First Year (1st Year) 2024 August 2106000102010101 Pathology Paper I February2024 Previous Year Question Paper || Download More Latest Question Papers and Study Materials Please Download Our Latest MBBSQuestion Bank App in Playstore

This post was last modified on 06 April 2025

VNSGU MBBS Last 15 Years 2010-2025 Previous Question Papers (Veer Narmad South Gujarat University)


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2106000102010101

Examination February – March 2024

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SECOND MBBS

PATHOLOGY (PAPER - I ) - LEVEL 1

[Time: Three Hours] [Max. Marks: 100]

Instructions:

  1. Fill up strictly the following details on your answer book
    1. Name of the Examination: SECOND MBBS
    2. --- Content provided by​ FirstRanker.com ---

    3. Name of the Subject: PATHOLOGY (PAPER - I) - LEVEL 1 (OMR)
    4. Subject Code No: 2106000102010101
  2. Sketch neat and labelled diagram wherever necessary.
  3. Figures to the right indicate full marks of the question.
  4. --- Content provided by‌ FirstRanker.com ---

  5. All questions are compulsory.

SECTION - I

Q.1 Multiple choice questions (MCQs). 20*1=20

(Instruction: Encircle the correct answer)

  1. Mitochondrial DNA differs from Nuclear DNA in:
    1. Being linear and open ended
    2. --- Content provided by⁠ FirstRanker.com ---

    3. Having two copies per somatic cell
    4. Monocistronic transcription pattern
    5. Having Maternal inheritance pattern
  2. Wear and Tear pigment is:
    1. Lipofuscin
    2. --- Content provided by FirstRanker.com ---

    3. Haemosiderin
    4. Melanin
    5. Bilirubin
  3. Dystrophic calcification is seen in:
    1. Hypervitaminosis D
    2. --- Content provided by‍ FirstRanker.com ---

    3. Williams Syndrome
    4. Atheromatous Plaque
    5. Renal tubular acidosis
  4. Bradykinin effects include all the following EXCEPT:
    1. Smooth muscle contraction
    2. --- Content provided by‍ FirstRanker.com ---

    3. Vasoconstriction
    4. Increased Vascular permeability
    5. Pain
  5. Wound contraction is mediated by:
    1. Collagen
    2. --- Content provided by⁠ FirstRanker.com ---

    3. Elastin
    4. Myofibroblast
    5. Granulation tissue
  6. Fifth sign of Inflammation " Functiolaesa "was given by :
    1. Celsus
    2. --- Content provided by​ FirstRanker.com ---

    3. Hunter
    4. Virchow
    5. Cohnheim
  7. Apoptosis is inhibited by :
    1. P53
    2. --- Content provided by FirstRanker.com ---

    3. n-myc
    4. Ras
    5. bcl2
  8. The most potent antigen presenting cell for T lymphocytes is :
    1. Dendritic cell
    2. --- Content provided by⁠ FirstRanker.com ---

    3. NK cell
    4. Stem cell
    5. Macrophage
  9. Type I hypersensitivity reaction is mediated by:
    1. IgG antibody
    2. --- Content provided by​ FirstRanker.com ---

    3. IgM antibody
    4. IgE antibody
    5. IgA antibody
  10. Red infarct is seen in all EXCEPT:
    1. Lung
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    3. Liver
    4. Intestine
    5. Spleen
  11. Caisson disease is due to:
    1. Fat embolism
    2. --- Content provided by‍ FirstRanker.com ---

    3. Air embolism
    4. Thromboembolism
    5. Amniotic fluid embolism
  12. Venous thrombus is associated with following feature:
    1. Tendency to embolise
    2. --- Content provided by FirstRanker.com ---

    3. Associated with atheroma
    4. Often with turbulence
    5. Commonly Mural
  13. Syphilitic involvement of aorta is observed mostly in:
    1. Descending aorta
    2. --- Content provided by‍ FirstRanker.com ---

    3. Arch of Aorta
    4. Abdominal Aorta
    5. Bifurcation of Aorta
  14. Bombay Phenotype are the individuals who:
    1. Lack of H genes and therefore H substance
    2. --- Content provided by⁠ FirstRanker.com ---

    3. Possess A and B antigen
    4. Secrete excessive amount of H substance
    5. Lack C, D, E antigens
  15. "Tombstone" appearance of cells is seen in which type of Necrosis?
    1. Fibrinoid
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    3. Coagulative
    4. Liquefactive
    5. Fat
  16. Which of the following is malignant tumour?
    1. Papilloma
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    3. Melanoma
    4. Adenoma
    5. Osteoma
  17. Which one of the following is an example of Metaplasia?
    1. Changes in skeletal muscles in athelets
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    3. Changes in Cardiac muscles due to hypertension
    4. Barret's Oesophagus
    5. Hormonal changes in breast and uterus during Pregnancy.
  18. Hypercalcaemia is associated with all of the following tumours EXCEPT:
    1. Small cell carcinoma of the lung
    2. --- Content provided by‍ FirstRanker.com ---

    3. Squamous cell carcinoma of Lung
    4. Adult T cell Leukaemia
    5. Renal cell carcinoma
  19. Placental alkaline Phosphatase is raised in:
    1. Teratoma
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    3. Seminoma
    4. Endodermal Sinus tumour
    5. Lymphoma Testis
  20. Role of L- selectin in inflammation:
    1. Rolling
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    3. Adhesion
    4. Homing
    5. Transmigration

SECTION - II

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Q.2 Case based question (compulsory to attempt) 13

45 yrs male, intravenous drug abuser presented with weight loss, oral candidiasis, generalized lymphadenopathy and symptoms of multiple opportunistic infections.

  1. What is your Probable diagnosis? 1
  2. Enumerate the investigations carried out to support the diagnosis? 4
  3. Describe the pathogenesis of the disease. 5
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  5. Describe the Natural History and stages of the Disease 3

Q.3 Long Essay Questions 27

(Attempt any 3 out of 4)

  1. Define Apoptosis. Describe the molecular mechanisms of Apoptosis. 1+5+3

    Illustrate contrasting features of Apoptosis from Necrosis.

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  3. Define Shock. Enumerate the classification and etiology of Shock. 1+2+3+3

    Describe the pathogenesis of Septic Shock. Describe the stages of Shock.

  4. Define Metastasis. Write three different routes of Metastasis. 1+3+5

    Describe cell biology of Invasion and Metastasis Cascade.

  5. Describe the pathogenesis of Cell Injury. Write the distinguishing features of Reversible and Irreversible Cell Injury. 5+4
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SECTION – III

Q.4 (Attempt any 8 out of 10) (5 marks Each) 40

  1. Difference between Transudate and Exudate.
  2. Describe healing by First intention (Primary Union)
  3. Enumerate the Liver Function tests and explain the clinical significance of each.
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  5. Enumerate the contrasting features of initiator and promoter carcinogens.
  6. Describe Mismatched blood transfusion.
  7. Difference between Kwashiorkor and Marasmus.
  8. Define Edema. Write pathophysiology of Edema.
  9. Clinical features and cytogenetic abnormalities of Down Syndrome.
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  11. Enumerate special stains in Amyloidosis.
  12. Describe Paraneoplastic syndrome.

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