RAN-2106000102010101
Second Year M.B.B.S. Examination January - 2023
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Pathology: Paper-1 (CBME New course)
[Time: 3 Hours ] [Total Marks: 100
? : / Instructions
(1) ? ? ? ? ? ? ? ?.
Fill up strictly the details of signs on your answer book
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Name of the Examination:
Second Year M.B.B.S.
Name of the Subject:
Pathology: Paper-1 (CBME New course)
Subject Code No.: 2106000102010101
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(2) Each question carries one mark.
(3) Encircle the correct answer
SECTION-I
Q-1 Multiple choice questions (*no negative markings) 20
- A 60-year male presented with pain in chest, radiating to left arm. Treating cardiologist found occlusion of coronary vessels during angiography. Which type of necrosis is seen in heart this condition?
- Fat necrosis
- Caseous necrosis
- Coagulative necrosis
- Colliquative necrosis
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- Bradykinin causes:
- Vasoconstriction
- Pain at the site of inflammation
- Bronchodilatation
- Decreased vascular permeability
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- Brown atrophy is due to:
- Fatty necrosis
- Hemosiderin
- Lipofuscin
- Ceruloplasmin
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- HLA is present on:
- All nucleated cells
- Only on cells of immune system
- Only on B cell
- Only on T cell
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- If both parents are carrier of sickle cell anaemia, then the likelihood of offspring having disease is:
- 10%
- 50%
- 25%
- 100%
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- All the following about tumor markers are properly matched except:
- Prostate cancer-PSA
- Colon cancer-CEA
- Ovarian cancer-CA-125
- Cholangiocarcinoma -AFP
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- Best marker for SLE is
- Anti Sm antibody
- Anti- dsDNA antibody
- Anti-histone antibody
- Anti-chromatin antibody
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- A 48 Year female presented with bone pain had Hepatosplenomegaly. Biopsy of Spleen showed Crumpled paper appearance. Which product is likely to have accumulated:
- Glucocerebroside
- Sphingomyelin
- Sulfatide
- Ganglioside
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- Which is not a tumour suppressor gene:
- WT-1
- P53
- Rb
- Ras
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- lack of differentiation is called:
- Anaplasia
- Dysplasia
- Metaplasia
- Hyperplasia
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- Which one is not the precancerous condition?
- Crohn's disease
- Ulcerative colitis
- Leukoplakia
- Xeroderma pigmentosum
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- Oedema occurs when protein level is below:
- 8mg/dl
- 2 mg/dl
- 5 mg/dl
- 10 mg/dl
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- Urine pH normally ranges from:
- 4.0 to 9.0
- 4.5 to 7.0
- 4.5 to 8.0
- 5.0 to 6.0
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- Chicken fat clot
- Post-mortem clot
- Thrombus
- Infarct
- All the above
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- The characteristic features of apoptosis on light microscopy is:
- Cellular swelling
- Nuclear Condensation
- Intact cell membrane
- Cytoplasmic eosinophilia
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- Which of the following regarding Bombay blood group is false :
- Lack of H, A and B antigen on RBC
- Lack of H, A and B substance in saliva
- Lack of antigen of several blood group system
- H, A and B antibodies will always be present in serum.
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- Pale infarct is seen in all except:
- Lung
- Kidney
- Spleen
- Heart
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- Lardaceous spleen is due to deposition of amyloid in:
- Sinusoids of red pulp
- White pulp
- Pencillary artery
- Splenic trabeculae
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- Most common viral antigen used for diagnosis of HIV in blood before transfusion is:
- p24
- p7
- pl7
- pl4
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- Lipid in tissue detected by:
- PAS
- Oil red O
- Myeloperoxidase
- Mucicarmine
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SECTION- II (40 Marks)
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Q-2 Case based long essay questions 13
A 65-year-old lady with a known case of Diabetes mellitus brought to the clinic in an unconscious state. She had high grade fever and haematuria for the past 2 days. On examination her blood pressure was 70/30 mm Hg and the temperature was 100.5* F with tachypnoea. Laboratory study revealed WBC count of 30,000 /µL with 90% neutrophil and shift to left. Platelet count was 50,000/µL. Urine analysis revealed many gram-negative organisms.
- What is the most likely diagnosis? 2 Marks
- Enumerate various types of the given condition 2 Marks
- Describe the pathophysiology of the given condition 4 Marks
- Describe morphological features of the given condition 5 Marks
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Q-3 Long essay questions. (Attempt any three) 27
- Describe etiology of Cell injury. Describe morphology of Cell injury.
- Define Hypersensitivity reactions. Describe etiology, pathogenesis, and examples of Type-1 Hypersensitivity reactions.
- Define and classify Amyloidosis. Describe pathogenesis and methods of demonstration of Amyloid.
- Define Inflammation and write cardinal signs of Inflammation. Describe vascular and cellular events of Acute Inflammation.
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SECTION- III (40 Marks)
Q-4 Short notes (Attempt Any 8) 40
- Enumerate Blood components and mention their uses and storage
- Exfoliative cytology.
- Describe CSF picture in Tuberculous meningitis.
- Down's syndrome.
- Viral oncogenesis.
- Pathological calcification.
- Describe factors affecting Wound healing.
- Granulomatous inflammation.
- Etiopathology and sequel of Obesity.
- Compare gross and microscopic features of Benign and Malignant tumours.
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This download link is referred from the post: VNSGU MBBS Last 15 Years 2010-2025 Previous Question Papers (Veer Narmad South Gujarat University)
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