Download VNSGU MBBS RAN 2106000102010102 Pathology Paper II January2023 Question Paper

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RAN-2106000102010102

Second Year M.B.B.S. Examination January - 2023

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Pathology: Paper -II (Set - I)

(CBME New course)

[ Time: 3 Hours ] [ Total Marks: 100 ]

? : / Instructions

(1) ? ? ? ? ? ? ? ?.

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Fill up strictly the details of signs on your answer book

Name of the Examination:

Second Year M.B.B.S.

Name of the Subject:

Pathology: Paper -II (Set - I) (CBME New course)

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Subject Code No.: 2106000102010102 Student's Signature

(2) Each question carries one mark

(3) Encircle the correct answer

[ Time: 20 Min. ] [ Total Marks: 20 ]

SECTION- I

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Q-1 Multiple choice questions (*no negative markings) (20)

1. Barrett's oesophagus shows:
   1. Intestinal dysplasia
   2. Intestinal metaplasia
   3. Columnar cell metaplasia
   4. Columnar cell dysplasia

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2. Councilman bodies are seen in:
   1. Wilson's disease
   2. Alcoholic hepatitis
   3. Acute viral hepatitis
   4. Autoimmune hepatitis

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3. Which of the following testicular tumor is not a germ cell neoplasm:
   1. Seminoma
   2. Yolk sac tumor
   3. Sertoli cell tumor
   4. Teratoma

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4. Red cell distribution width (RDW) used for estimation of:
   1. Poikilocytosis
   2. Anisocytosis
   3. Hypochromia
   4. Macrocytosis

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5. A patient presented with osteomyelitis with sickle cell anemia. What will be the most common causative organism?
   1. Salmonella
   2. Staphylococcus aureus
   3. H. influenza
   4. Enterobacteria

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6. All are decreased in iron deficiency anemia except:
   1. Serum ferritin
   2. TIBC
   3. Transferrin saturation
   4. Hepcidin

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7. An epiphyseal bone lesion is:
   1. Osteogenic sarcoma
   2. Chondroblastoma
   3. Osteoma
   4. Chondromyxoid fibroma

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8. Mucinous cystadenoma of ovary arises:
   1. From cystic teratoma
   2. From surface coelomic epithelium
   3. From sex cord stromal cells
   4. From ectopic mucin secreting glands

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9. Most common carcinoma of breast is:
   1. Intraductal carcinoma
   2. Colloid Carcinoma
   3. Lobular Carcinoma
   4. Sarcoma phyllodes

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10. A 65-year-old male presented with fatigue. His fasting sugar was 110 mg%, post prandial sugar was 180 mg%, HBA1C was 6.1%. Diagnosis will be
    1. Prediabetes
    2. Stress induced
    3. Impaired glucose tolerance
    4. Diabetes mellitus

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11. Transverse ulcers are seen in:
    1. Typhoid
    2. Tuberculosis
    3. Amebiasis
    4. Ulcerative colitis

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12. Flea bitten appearance of kidney seen in:
    1. Malignant hypertension
    2. Benign hypertension
    3. Chronic pyelonephritis
    4. Diabetes mellitus

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13. Which of the following is associated with destruction of valves?
    1. Acute infective endocarditis
    2. Libman sacks endocarditis
    3. Rheumatic heart disease
    4. All the above

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14. All are obstructive lung disease except:
    1. Emphysema
    2. Interstitial fibrosis
    3. Asthma
    4. Bronchiectasis

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15. Verocay bodies are seen in:
    1. Meningioma
    2. Glioma
    3. Medulloblastoma
    4. Schwannoma

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16. Most common site of artery of atherosclerosis:
    1. Left anterior descending artery
    2. Right coronary artery
    3. Left circumflex artery
    4. Diagonal branch of left anterior descending artery

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17. Pleural mesothelioma is associated with:
    1. Asbestosis
    2. Berylliosis
    3. Silicosis
    4. Bagassosis

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18. Subepithelial humps are characteristic of
    1. Minimal change disease
    2. Membranous glomerulonephritis
    3. Membranoproliferative glomerulonephritis
    4. Post streptococcal glomerulonephritis

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19. A 70-year-old male has abdominal pain with a mass in abdomen. Angiography reveals an aneurysm of the aorta. Most likely cause is:
    1. Syphilis
    2. Trauma
    3. Atherosclerosis
    4. Congenital

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20. Smudge cells in the peripheral smear are characteristic of:
    1. Chronic myeloid leukemia
    2. Chronic lymphocytic leukemia
    3. Acute myelogenous leukemia
    4. Acute lymphoblastic leukemia

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[ Time: 2 Hours 40 Minutes ] [ Total Marks: 80 ]

SECTION- II (40 Marks)

Q-2 Case based long essay questions [13×1=13]

A 40-year-old male patient presented with history of chronic alcoholism, distended abdomen, and hematemesis. Liver function test showed reversed A/G ratio.

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1. What is possible diagnosis? 2 marks
2. Write pathogenesis of the disease 4 marks
3. Write gross and microscopic morphologic changes in the affected organ. 4 marks
4. Enumerate other clinical sequelae. 2 marks
5. List four etiological conditions other than alcohol causing this pathology 1 marks

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Q-3 Long essay questions. (Attempt any three) [9×3=27]

1. Define Atherosclerosis. Describe etiology, pathogenesis, and morphological features of Atherosclerosis. 1+2+3+3
2. Define Nephrotic syndrome. Write its causes and describe pathogenesis of glomerular injury. 1+3+5
3. Define emphysema. Describe etio-pathogenesis and morphology of various types of emphysema 1+3+5
4. Define and classify Anemia. Write laboratory diagnosis of megaloblastic anaemia 1+3+5

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Q-4 Short notes (Attempt Any 8) [8×5=40]

1. Describe morphological changes in Diabetic nephropathy.
2. Write morphological difference between Crohn's disease and Ulcerative colitis.
3. Describe gross and microscopic features of Colloid Goitre.
4. Miliary tuberculosis.

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5. Giant cell tumor of the bone.
6. Squamous cell carcinoma.
7. Serum cardiac marker.
8. Hodgkin's lymphoma.
9. Enumerate Plasma cell disorder. Write laboratory diagnosis of Multiple myeloma.

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10. Classify Germ cell tumour. Describe morphological features of Seminoma

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