RAN-3715
SECOND YEAR M.B.B.S. Examination
December / January - 2019 / 2020
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PHARMACOLOGY PAPER II
Time: 2 Hours ] &p>
Q.1. Answer very briefly :
- Mention two topically used corticosteroids.
- Name two drugs which can be used for medical closure of patent ductus arteriosus.
- Describe the mechanism of action of ethanol in management of methanol poisoning.
- What is second gas effect in relation to general anesthetic agents?
- Name two hepatotoxic antimicrobials.
- Name two drugs useful in the treatment of neurocysticercosis.
- Why is chloroquine useful in hepatic amoebiasis but not in intestinal amoebiasis?
- Explain why gastric lavage is performed in morphine poisoning even if the drug has been taken intravenously.
- Describe the difference between antiseptic and disinfectant giving one example of each.
- Explain how voglibose differs from acarbose
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Q.2. Answer any four :
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- Enumerate the advantages of human insulin over regular insulin.
- Describe the role of morphine in LVF.
- Comment on fixed dose combination of ampicillin and cloxacillin meant for treatment of infection
- Explain mechanism of action of estrogen +progesterone combination as contraceptive drug.
- Name one preferred drug each for the following conditions and mention adverse effects of each.
- Tinea solium infection
- Acute filariasis
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Section - II
Q.3. Answer any four of the following:
- Enlist different drugs used for the treatment of migraine. Write the drug therapy for an acute attack of migraine.
- Describe the management of paracetamol poisoning.
- Write a short note on the management of diabetic ketoacidosis.
- Describe the mechanism of action, advantages and disadvantages of use of radioactive iodine in hyperthyroidism.
- Describe briefly the mechanism of action, uses and adverse effects of rifampicin.
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Q.4. Answer any two of the following:
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- Classify drugs used in treatment of hyperthyroidism. Describe the mechanism of action, and adverse effects of any four drugs (from different groups) that you have mentioned.
- Describe the pharmacotherapy of Parkinsonism.
- Describe the drug therapy of P- falciparum malaria.
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