Download KUHS (Kerala University of Health Sciences) MBBS (Bachelor of Medicine, Bachelor of Surgery) 2nd Year Microbiology Syllabus
Edition. Jaypee brothers Medical Publishers
4. Principles and practice of Forensic medicine.Dr.B. Umadethan 2008, Swami Law
Publishers.
5. Parikhs Text Book of Medical Jurisprudence, forensic medicine and Toxicology, 6th
edition, CBS Publishers and Distributors.
7 .J.B. Mukherjee's forensic medicine and Toxicology. R.N. Karmakar 2007.
Evaluation
Internal assessment examinations may be conducted as per the discretion. examination per
semester, without violating MCI norms. : Minimum one
Theory
40
Internal assessment
10
Viva
10
Total
60
Practicals
30
Intrenal Assessment
10
Total
40
Grand Total
100
Topics and mark allotment
Medical jurisprudence
20%
(Ethics to be given due importance)
Court and legal procedures
10%
Thanatology, M/L autopsy
8%
Asphyxial deaths
10%
Traumatology
10%
Sexual jurisprudence
20%
Infanticide
10%
Trace evidences
5%
Forensic psychiatry
2%
Toxicology
5%
MICROBIOLOGY
A. GOAL
The broad goal of the teaching of undergraduate students in Microbiology is to
provide an understanding of the natural history of infectious diseases in order to deal with
the etiology, pathogenesis, laboratory diagnosis, treatment and control of infections in the
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community.
B.OBJECTIVES
1. Knowledge
At the end of the course, the student shall be able to
i. State the infective microorganisms of the human body and describe the host parasite
relationship
ii. List pathogenic microorganisms (bacteria, viruses, parasites, fungi) and describe the
pathogenesis of the diseases produced by them
iii. State or indicate the mode of transmission of pathogenic and opportunistic organisms and
their sources including insect vectors responsible for transmission of infection
iv. Describe mechanisms of immunity to infections
v. Acquire knowledge on suitable antimicrobial agents for treatment of infections and scope
for immunotherapy and different vaccines available for prevention of communicable
diseases
vi Antibiotic policy/stewardship
vii.National control programs for infectious diseases. Eg. RNTCP, Malaria control
program,STDs, NACO, Immunisation program.
viii Apply methods of disinfection and sterilization to control and prevent hospital and
community acquired infections
vii. Recommend laboratory investigations regarding bacteriological examination of
food, water, milk and air.
2. Skills
At the end of the course the student shall be able t
1. Plan and interpret laboratory investigations for the diagnosis of infectious diseases
and to correlate the clinical manifestations with the etiological agent
2. Identify the common infectious agents with the help of laboratory tests and determine
the efficacy of antimicrobial agents against them.
3. Perform commonly employed bedside tests for detection of infectious agents such as
blood film for malaria, filaria, gram staining, Acid Fast Bacilli (AFB) staining and stool
sample of ova cyst etc.
4. Use the correct method for collection, storage, and transport of clinical specimens
for microbiological investigations.
5. .To learn to use the principles of evidence based discision making of microbiological tests.
3. Integration
The student shall understand infectious diseases of national importance in relation to
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clinical, therapeutic and preventive aspects
C. DETAILED SYLLABUS
Duration of the course: 3 semesters-III, IV, V Total Number of Hours: 250 Lectures: 80
Practicals: 80 Innovative sessions: 90 (Project work, Seminars, Structures discussions,
Integrated teaching, Formative evaluation, revision)
(The teaching should stress on Pathogenesis, Laboratory diagnosis, sterilization and
disinfection, infectious diseases common in Kerala and India, Hospital infection, antibiotic
use, Principles of immune prophylaxis and immunotherapy and applied and clinical
microbiology. Basic morphology and life cycle of parasites required for lab diagnosis.
Certain portions to be deleted--Detailed morphological, cultural, Biochemistry, and
Antigenic characters,)
DETAILS OF LECTURES
80hrs
I. General microbiology
12hrs
Introduction to microbiology
Morphology of bacteria comparison with other microbial forms
Growth, nutrition culture media
Identification of bacteria
Bacterial genetics
Antibacteial agents and antibiotic sensitivity test
Infection-Source and spread of infection
Sterilisation and disinfection
Response to microbial infections
25 hrs
II.Systematic bacteriology
1. Gram positive Cocci-Stapohylococci, Streptococci, Pneumococci
2. Gram negative Cocci-Neisseria
3. Gram Positive Bacilli-Corynebacterium, Listeria, Bacillus
4. Mycobacteria, Nocardia, Actinomyces
5. Clostridia, Nonsporing anaerobes.
6. Gram negative Bacillus-Haemophilus, Bordetella, Brucella, Enterobacteria/Yersinia
7. Pseudomonas,Pasteurella,Acinetobacter
8. Vibrio/Campylobacter
9. Mycoplasma, Legionella, Rickettsia, Chlamydia
10. Spirochetes
III.Virology
15 hrs
1. General characteristics of viruses.
2. Virus host interaction
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3. Replication of virus
4. Pox virus, Herpes, Adenovirus
5. Papova, Retrovirus
6. Myxoviruses
7. Picorna virus
8. Hepatitis, Miscellaneous
9. Rhabdo virus
10. Arboviruses
11. Oncogenic viruses
12.HIV
13. Bacteriophages
IV.Immunology
12hrs
1. Introduction Classification, type and cells involved in immunity
2. Antigen, Antibodies
3. Complement in health and diseases
4. Hypersensitivity
5. HLA antigens in health and diseases
6. Immunodeficiency diseases
7. Serological test in medical practice
8. Auto immunity
9. Tumour and transplantation immunology
10. Immunoprophylaxis and immunotherapy
11.Immunohaematology
V.Parasitology (Topic presentation)
12 hrs
1. Introduction of parasitic disease
2. Protozoal infections-Amoebiasis, Plasmodium,Leishmaniasis, Trypanosoma,
Giardia, Balantidium, Cryptosporidium, Trichomonas, Toxoplasma,
Pneumocystis-laboratory diagnosis of protozoal infection
3. Helminthus-intestinal nematodes, tissue nematodes,cestodes, trematodes-
Laboratory diagnosis of helminthic infections
VI.Mycology
4 hrs
1. Introduction-Classification of fungi and general principles of lab diagnosis
2. Superficial infections
3. Subcutaneous infections-Mycetoma, Rhinosporidiosis
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DETAILS OF PRACTICALS AND DEMONSTRATION
40 hrs
1. Techniques Simple stain, Gram Stain, Ziehl ?Neelsen stain,
Fungus Lactophenol cotton blue,
Parasitology stool examination
2. Clinical microbiology (Demonstration cum practical)
60hrs
a.
Oropharyngeal infection
b.
Wound infection
c.
Respiratory tract infections
d.
Meningitis
e.
Gastro intestinal infections
f.
Urinary tract infections
g.
Urethritis
h.
Blood culture techniques
i.
Equipments/Instruments
j.
Interpretation of lab results
k
Infection control measures
l
Community outbreak investigation and control measures
m
Antibiotic stewardship and antibiotic policy
APPL IED MICROBIOLOGY (Discussion and Integrated teaching)
60hrs
1. Upper respiratory tract infections, infections of eye and ear
2. Pneumonia, Tuberculosis, Bronchitis-Aetiology, lab diagnosis, Prophylaxis
3. Rheumatic fever-Endocarditis, Myocarditis
4. Urinary tract infections
5. Enteric fever-P.U.O
6. Gastroenteritis-Cholera, other causes
7. Osteomyelitis-Arthritis, TB of bone
8. Meningitis, Pyogenic, Aseptic
9. Opportunistic infections
10. Sexually transmitted diseases
11. Hospital infection
12. Antimicrobial agents
TUTORIAL
10hrs
1. Normal flora
2. Anaerobic infections
3. Collection, transportation and preliminary processing of specimens
4. Laboratory diagnosis of viral infections
5. Investigations of epidemics in the hospital and community
TEXTBOOKS RECOMMENDED
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Prescribed Books
1. Textbook of Microbiology by R. Anantha
Narayanan and C.K.J. Paniker 7th Edition Orient
Longman
2. A guide to Microbial Infections,
Pathogenesis, Immunology, Laborator
diagnosis and Control by Greenwood.
Slack and Penthera
3. Essentials of Medical Microbiology, Apurba Sankar Sastry, Sandhya Bhatt.K
4. Textbook of Microbiology and Immunology,Subash Chandra Parija
5. Textbook of Parasitology by C. K. J. Paniker / Chakraborthy /Pareja
6. Textbook of Parasitology by Chatterjee.
Reference Books
1. Medical Microbiology by Jawetz E, Melnick J L, Adelberg E A
2. Textbook of Immunology, Kuby
EVALUATION: There should be regular formative assessment
Internal assessment : The internal assessment marks for Microbiology are 15 for
Practical and15 for Theory. Since the minimum required for appearing for University
exam is 35% the total minimum marks required for internal assessment would be 5.5 out
of 15, There need to be a separate minimum for Practical and Theory internal
assessment.
The total marks for Microbioloy is 150 (Theory 80 (2 papers) + Viva 15 + Practical 25 +
internal assessment 30).
The pass has to be decided as follows:
1. A candidate must obtain minimum 50% marks separately for University theory
examination
2. A candidate must obtain minimum 50% marks separately for University practical
examination
3. Total aggregate marks should be 75 out of 150marks or more for pass.
4. Theory and Practical Internal assessment marks should be added to the marks
obtained in Theory and Practical University exams respectively for deciding the pass
5. For Theory (80 + 15 viva+ 15 marks internal assessment = 110) the minimum for
pass should be 55marks.
6. For Practical (25 + 15 marks internal assessment = 40) the minimum for pass should be
20 marks
Microbiology-Two papers of 2 hour duration of 40 marks each
Microbiology paper I-General bacteriology, Immunology, &
systematic bacteriology.
Structured Essay =
10 marks
Short Essays (2 X5) =
10 marks
80
Short answer questions (10 X2) = 20 marks
Total =
40 marks
Microbiology Paper II ? Virology, Parasitology, Mycology, Clinical Microbiology
Structured Essay = 10 marks
Short Essays (2 X5) = 10 marks
Short answer questions (10 X2) = 20 marks
Total =
40 marks
Total marks (40 + 40) = 80 marks
Internal assessment = 15 marks
Viva voce = 15 marks
Total for theory = 110 marks
(Duplication of the questions should be avoided)
Practicals
Internal assessment -15 marks. University ?25 marks
University Practical -Exercises
1. Gram staining (Clinical material) ? 5marks
2. AFB staining (Clinical Material) ? 5 marks
3. Applied microbiology ? 5 marks
4. Spotters-10 numbers ? 10 marks (preferably OSPE)
2 minutes for each spotter, 2-4 sub questions with each spotter.
(2 Mycology, 3 Parasitology, 2 General Bacteriology, 2
Virology/Immunology & 1 Clinical Bacteriology)
PATHOLOGY
GOALS
The broad goal of teaching undergraduates Pathology is to impart the knowledge
skills and attitudes in the learner to understand the etiopathogenesis, morphology and
pathological concepts related to various common diseases.
Learning Objectives
At the end of the course, the learner shall be able to:
1. Know the principles of collection, handling, storage and dispatch of clinical samples
from patient, in a proper manner.
2. Perform and interpret in a proper manner the basic clinico-pathological procedures.
3. Have an understanding of the common hematological disorders and the
investigations necessary to diagnose them and determine their prognosis.
4.Understand the concept of cell injury, the change produced thereby, in different tissues
and organs and the body capacity for healing.
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This post was last modified on 06 August 2021