[MBBS 0222]
FEBRUARY 2022
Sub.Code :5061
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M.B.B.S. DEGREE EXAMINATION
(For the candidates admitted from the Academic Year 2018-2019)
SECOND YEAR
PAPER I – PHARMACOLOGY - I
Time: Three hours
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Q.P. Code: 525061
Maximum : 40 Marks
Answer All Questions
I. Elaborate on:
(1 x 10 = 10)
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- A 49 years old male is brought to the emergency dept with symptoms suggestive of classic angina.
- What are the various classes of drugs useful to treat the above patient?
- Discuss in detail with suitable diagram on the mechanism of vascular smooth muscle relaxant effect of nitrates and its therapeutic uses.
- Add a note on Nicorandil.
II. Write notes on:
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(6 x 4 = 24)
- Enumerate atypical antidepressants. Discuss their mechanism of action and clinical uses.
- Write in detail on transdermal therapeutic system with examples, advantages and disadvantages.
- Write in detail on erythrocyte maturation factors and their role on treatment of anemia.
- Probeneci
- Ketamine.
- Nicotinic aci
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III. Short answers on:
(6 x 1 = 6)
- Eprosartan and the mechanisms by which it lowers the blood pressure.
- Cilostazol.
- Side effects of potassium channel blockers used in the treatment of cardiac arrhythmias.
- EMLA.
- Phase III clinical trial.
- Define tachyphylaxis. Give examples.
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