Download MBBS First Year Biochemistry Paper II MCQs 2022 Question Paper

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M.B.B.S. DEGREE EXAMINATION

(For the candidates admitted from the Academic Year 2019-2020)

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FIRST YEAR

PAPER II - BIOCHEMISTRY

MULTIPLE CHOICE QUESTIONS

O.P. Code: 526056

Time: 30 Minutes Maximum : 20 Marks

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Answer All Questions

Choose one correct answer in the box provided in the Answer Script. No overwriting should be done.

I. Multiple Choice Questions: (20x1=20)

1. Normal blood calcium level is

   1. 5-7mg/dl

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   2. 7-9mg/dl
   3. 9-11mg/dl
   4. 11-13 mg/dl

2. Which is attached to 3’ ( prime ) end of mRNA after transcription

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   1. Poly A tail.
   2. CCA sequence.
   3. 7 —Methylguanosine.
   4. Intron.

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3. Among the following the most sensitive indicator of glomerular function is

   1. Serum urea.
   2. Serum creatinine.
   3. Urea clearance.
   4. Creatinine clearance.

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4. Albinism is due to deficiency of which enzyme

   1. Tyrosinase.
   2. Tyrosine hydroxylase.
   3. Phenylalanine hydroxylase.

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   4. Homogentisate oxidase.

5. Which enzyme deficiency causes LESCH NYHAN SYNDROME

   1. Transcarboxylase.
   2. HGPRTase.

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   3. Glutaminase.
   4. PRPP synthetase.

6. Which is Nucleotide

   1. Nitrogenous base + Sugar

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   2. Nucleoside + Phosphate
   3. Nucleoside + Phosphate
   4. Nucleoside + Sugar

7. The aminoacid from

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   1. Tryptophan.
   2. Tyrosine.
   3. Threonine.
   4. Histidine.

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8. Phenyl butyrate is used in urea cycle disorders because it ?

   1. Activates enzymes.
   2. Maintains renal output.
   3. Maintains energy level.
   4. Increases renal excretion of Ammonia.

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9. Which of the following proteins are abundant in the extracellular matrix?

   1. Actin.
   2. Myosin.
   3. Tubulin.

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   4. Collagen.

10. Glycine is used for synthesis of all the following compounds except

    1. Heme.
    2. Creatinine.

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    3. Purine ring.
    4. Pyrimidine ring.

11. Keshan’s disease is due to deficiency of

    1. Chromium.

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    2. Selenium.
    3. Magnesium.
    4. Copper

12. In acute pancreatitis, the activity of the following enzyme in plasma is specifically elevated

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    1. Alanine aminotransferase.
    2. Aspartate aminotransferase.
    3. Amylase.
    4. Creatine kinase.

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13. Which of the following is not a nutritionally essential aminoacids for humans ?

    1. Leucine.
    2. Tryptophan.
    3. Tyrosine.
    4. Methionine.

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14. Which of the following is a structural component of RNA but not of DNA ?

    1. Adenine.
    2. Uracil.
    3. Guanine.

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    4. Thymine.

15. Ehler-Danlos syndrome is due to

    1. Abnormality in gene for procollagen.
    2. Defect of elastase.

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    3. Deficiency of prolyl hydroxylase.
    4. Deficiency of lysyl hydroxylase.

16. GABA ( Gamma amino butyric acid ) is

    1. Post synaptic excitatory transmitter

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    2. Post synaptic inhibitory transmitter
    3. Activator of glia cell formation.
    4. Inhibitor of glia cell formation.

17. Which of the following is initiator codon for Translation ?

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    1. UAA.
    2. UAG.
    3. AUG.
    4. UGA.

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18. Casein, the milk protein is

    1. Nucleoprotein.
    2. Chromoprotein.
    3. Phosphoprotein.
    4. Glycoprotein.

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19. Which of the following is the inhibitor of Thymidilate synthase enzyme ?

    1. Methotrexate.
    2. Allopurinol.
    3. 5 —Fluorouracil.

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    4. Hydroxy urea.

20. At isoelectric pH, the proteins show

    1. Maximum net charge.
    2. Maximum mobility in electric field

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    3. Maximum precipitability.
    4. Minimum buffering action.

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