INFECTION PREVENTION&
TRANSPORTATION IN
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NEONATOLOGYINFECTION CONTROL IN NICU-LEARNING
OBJECTIVES
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Improved hand hygiene compliance
Barrier precautions/ Barrier nursing
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Reduction of environmental contaminationAntibiotic restriction policies
HAND HYGIENE IN HEALTHCARE
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SETTINGS: AN OVERVIEW. Background
. Definitions
. Indications
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. Selection of Agents. Techniques
Guideline for Hand Hygiene in Health-care Settings. MMWR 2002;
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vol. 51, no. RR-16.SO WHY ALL THE FUSS ABOUT HAND
HYGIENE?
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Most common mode of transmission
of pathogens is via hands!
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............and the reason for.Infections acquired in healthcare
.Spread of antimicrobial resistance
EVIDENCE OF RELATIONSHIP BETWEEN HAND
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HYGIENE &HEALTHCARE-ASSOCIATED INFECTIONS
. Substantial evidence:
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hand hygiene reduces the incidence of infections
. More recent studies: rates lower when antiseptic
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handwashing was performedGuideline for Hand Hygiene in Health-care Settings. MMWR 2002;
vol. 51, no. RR-16.
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DEFINITIONS
Hand hygiene
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Performing handwashing, antiseptic handwash, alcohol-basedhandrub, surgical hand hygiene/antisepsis
Handwashing
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Washing hands with plain soap and water
Antiseptic handwash
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Washing hands with water and soap or other detergents containingan antiseptic agent
Guideline for Hand Hygiene in Health-care Settings. MMWR 2002;
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vol. 51, no. RR-16.
DEFINITIONS
Alcohol-based handrub
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Rubbing hands with an alcohol-containing preparation
Surgical hand hygiene/antisepsis
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Handwashing or using an alcohol-based handrub beforeoperations by surgical personnel
Guideline for Hand Hygiene in Health-care Settings. MMWR 2002;
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vol. 51, no. RR-16.
Procedural Handwashing
Procedural Handwashing
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Why hand washing?
Simply put...hand hygiene saves lives!
Hand washing is one of the "most important
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means of preventing the spread of infectionCDC Guidelines
FLORA ON HANDS
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Coagulase-negative staphylococciStaph aureus
Pseudomonas aeruginosa
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Entercococci
Candida spp
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COLONIZED OR INFECTED:WHAT IS THE DIFFERENCE?
People who carry bacteria without evidence of
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infection (fever, increased white blood cell count) are
colonized
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If an infection develops, it is usually from bacteria thatcolonize patients
Bacteria that colonize patients can be transmitted
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from one patient to another by the hands of
healthcare workers
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~ Bacteria can be transmitted even if thepatient is not infected ~
The Iceberg
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EffectInfected
Colonized
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The Inanimate Environment Can
Facilitate Transmission
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~ Contaminated surfaces increase cross-transmission ~Abstract: The Risk of Hand and Glove Contamination after Contact with a
VRE (+) Patient Environment. Hayden M, ICAAC, 2001, Chicago, IL.
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HAND WASHING...Hand washing is the no.1 prevention against spread of
ifetio,isideadoutside
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the hospital settig...Itis
the cornerstone of infection control practice and
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education for anyone who works in health careSummit Medical Center, Oakland, California
Hand washing can the first line of defense against many
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ifetiousdiseases...theAMAurges otoly
professionals but public also to adopt hand washing as
an important personal priority.
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American Medical Association House of Delegates Resolution
409
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DURATION FOR DIFFERENT TYPES OF HANDWASHINGTwo minutes
before entering the unit
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before performing any procedureafter handling any infected baby or secretions
15 seconds
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before and after touching every babyafter touching unsterile surfaces and fomites
Guideline for Hand Hygiene in Health-care Settings. MMWR 2002;
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vol. 51, no. RR-16.TYPE OF HAND HYGIENE
. When hands are visibly dirty, contaminated, or
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soiled,wash
with
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non-antimicrobial
or
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antimicrobial soap and water. Thereafter, use analcohol-based handrub
. If hands are not visibly soiled, use an alcohol-
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based handrub for routinely decontaminating
hands.
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Handwash followed by hand rub theoretically superior!Guideline for Hand Hygiene in Health-care Settings. MMWR 2002;
vol. 51, no. RR-16.
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SELECTION OF HAND HYGIENE AGENTS: FACTORS TO
CONSIDER
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Efficacy of antiseptic agentAcceptance of product by healthcare
personnel
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Characteristics of product
Skin irritation and dryness
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Accessibility of productDispenser systems
Guideline for Hand Hygiene in Health-care Settings. MMWR 2002;
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vol. 51, no. RR-16.
EFFICACY OF HAND HYGIENE
PREPARATIONS IN KILLING
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BACTERIA
Good
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BetterBest
Plain Soap
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Antimicrobial
Alcohol-based
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soaphandrub
Plain soap is
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just not enough
Ability of Hand Hygiene Agents to
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Reduce BaTi c
me te
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Afte r
r ia
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Disi o
n n
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fecti Ha
on
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nds%
log
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0 60
180 minutes
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99.9 3.099.0 2.0
Alcohol-based handrub
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(70% Isopropanol)
90.0 1.0
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Antimicrobial soap(4% Chlorhexidine)
0.0 0.0
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Plain soap
Baseline
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Adapted from: Hosp Epidemiol Infect Control, 2nd Edition, 1999.Effect of Alcohol-Based Handrubs on
Skin
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ConditionSelf-reported skin score Epidermal water content
Dry
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Healthy
6
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275
25
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4
23
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321
2
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19
1
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170
15
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Healthy
Dry
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Baseline2 weeks
Baseline
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2 weeks
Alcohol rub Soap and water
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Alcohol rubSoap and water
~ Alcohol-based handrub is less damaging to the skin ~
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Boyce J, Infect Control Hosp Epidemiol 2000;21(7):438-441.
TIME SPENT CLEANSING HANDS:
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ONE NURSE PER 8 HOUR SHIFT. Hand washing with soap and water: 56 minutes
? Based on seven (60 second) handwashing episodes per hour
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. Alcohol-based handrub: 18 minutes
? Based on seven (20 second) handrub episodes per hour
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~ Alcohol-based handrubs reduce time neededfor hand disinfection ~
Voss A and Widmer AF, Infect Control Hosp Epidemiol 1997:18;205-208.
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RECOMMENDED HAND HYGIENETECHNIQUE
Handrubs
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Apply to palm of one hand, rub hands together
covering al surfaces until dry
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Volume: based on manufacturerHandwashing
Wet hands with water, apply soap, rub hands
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together for at least 15 seconds
Rinse and dry with disposable towel
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Guideline for Hand Hygiene in Health-care Settings. MMWR 2002;vol. 51, no. RR-16.
REASONS FOR NONCOMPLIANCE
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. Handwashing agents cause irritation and dryness
. Sinks are inconveniently located/lack of sinks
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. Lack of soap and paper towels. Too busy/insufficient time
. Understaffing/overcrowding
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. Patient needs take priority
Adapted from Pittet D, Infect Control Hosp Epidemiol 2000;21:381-386.
GLOVING
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Wear gloves when contact with blood or other
potentially infectious materials is possible
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Remove gloves after caring for a patientDo not wear the same pair of gloves for the care of
more than one patient
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Do not wash gloves
Remember the glove is for the patient also !!!
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Guideline for Hand Hygiene in Health-care Settings. MMWR 2002;vol. 51, no. RR-16.
EDUCATION/MOTIVATION PROGRAMS
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Monitor healthcare workers (HCWs) adherence with
recommended hand hygiene practices and give
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feedbackImplement a multidisciplinary program to improve
adherence to recommended practices
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Encourage patients and their families to remind HCWs
to practice hand hygiene
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Guideline for Hand Hygiene in Health-care Settings. MMWR 2002;vol. 51, no. RR-16.
ADMINISTRATIVE MEASURES TO
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IMPROVE HAND HYGIENEMake improved hand hygiene an institutional
priority
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provide appropriate administrative support and
financial resources
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Place alcohol-based handrubs at entrance topatient room, or at bedside
Provide HCWs with pocket-sized containers
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Guideline for Hand Hygiene in Health-care Settings. MMWR 2002;
vol. 51, no. RR-16.
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PERFORMANCE INDICATORSMonitor and record adherence to hand
Provide feedback to healthcare workers about their
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performance
Monitor the volume of alcohol-based handrub used
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per 1,000 patient daysMonitor adherence to policies on wearing artificial
nails
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Guideline for Hand Hygiene in Health-care Settings. MMWR 2002;
vol. 51, no. RR-16.
SUMMARY
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ALCOHOL-BASED HANDRUBS:
WHAT BENEFITS DO THEY PROVIDE?
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Require less timeMore effective for standard handwashing than
soap
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More accessible than sinks
Reduce bacterial counts on hands
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Improve skin conditionBARRIER NURSING
CHAIN OF INFECTION
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The interaction betweenall the six elements of
the chain determine
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whether an infection wil
result
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INFECTION CONTROLSources of microorganisms can include:
Patients
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Health care workersVisitors
These sources can include:
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Persons with acute illness or infectionThose who are carriers, and
Those who are colonized with microorganisms (harbor the
organism without showing any apparent illness)
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Inanimate objects such as furniture and medical
equipment can also be sources of microorganisms.
OBJECTIVE ? BARRIER NURSING
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The main aim is to create a barrier to
the passage of infectious pathogenic
organisms between the contagious patient
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and other patients and staff in the hospitalWHAT DOES IT CONTAIN?
Ensure that patient care items, bedside equipment, and
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frequently touched surfaces receive daily cleaning
USE DEDICATED
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ThermometerB/P cuff
Stethoscope
Oxygen source & tubing
Suction tubings
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Antibiotics & other medicationsResuscitation kit
Baby tray
They must be cleaned daily
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BARRIER NURSING CONTD...BN reduces but does not completely eliminate the
possibility of infection
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BN is only effective if used correctly and at all times
where contact may occur
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The use of Barrier Nursing does not replace basichygiene measures such as hand-washing, it is still very
essential to prevent transmission.
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GOOD NICU PRACTICES
PREVENT ENTRY OF MICROBES INTO NICU
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PREVENT PROLIFERATION OF MICROBESPREVENT SPREAD OF MICROBES
PRACTICES ? PROTECTS NEWBORN FROM DEVELOPING
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INFECTION
PREVENT ENTRY OF MICROBES
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MAINTAINING A CLEAN ENVIRONMENT OUTSIDE NNN--
LABOUR ROOM
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BUFFER ZONEENTRY RESTRICTIONS?
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FAMILY MEMBERS
ENTRY OF INFECTED BABIES
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PERSONNEL OF NURSERYPERSONNEL OF ALLIED SERVICES
HAND WASHING ?SINGLE MOST IMPORTANT INTERVENTION
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GOWNS / MASKS /SLIIPERS
AIR CHANGES
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12 AIR CHANGES /HOURS0.5 BACTERRIAL FILTER
-
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PREVENT PROLIFERATION OF MICROBES IN
NNN
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EQUIPMENT DISINFECTIONGOOD HOUSE KEEPING--
FLOORS
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WALLS
FANS
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REFRIGERATORSINKS
BUCKETS
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PREVENTION OF SPREAD OF MICROBESBETWEEN BABIES
PREVENT OVER CROWDING--4-6 FEET SPACE
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STAFFING PATTERN--
1 :1
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MULTI DRUG RESISTANT ORGANISM1:2
SUSPECTED SEPSIS,SEPSIS WITH ORGANISMS
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SUSCEPTIBLE TO WIDE RANGE OF DRUGS.
1:3
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SEPTIC BABIES RECEIVED AB AND PRESENTLY NON ?INFECTIOUS
1:4
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STABLE BABIES
HAND WASHING
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DISPOSABLELAMINAR FLOW
PROHIBITING OF STOCK SOLUTIONS
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FOMITES- UNDERESTIMATED
FILES
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STETHOSCOPESEXAMINATION TRAY
PENS
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COFFEE/TEA MUGS
TELEPHONES
PROTECT NEW BORNS FROM DEVELOPING INFECTIONS
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BREAST FEEDS/MILK
INVOLVEMENT OF MOTHER
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EARLY DISCHARGE POLICYCORD CARE
SKIN CARE
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HANDLING OF PARENTERAL FLUID/ DRUGS
HANDLING OF INVASIVES LINES AND TUBES
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PERIPHERAL LINESCENTRAL LINES
REMOVING LINES
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MINIMIZE HANDLING.
ASEPETIC PRECAUTIONS DURING PROCEDURES
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HAND WASHING BEFOREINTRAVENOUS LINES
ET SUCTIONING
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ET INSERTION , L P, DVET, CENTRAL LINE INSERTION----
SAME SANCTITY AS SURGICAL PROCEDURE
PRACTICES ENABLE BETTER ADMINISTRATION
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ENVIRONMENT SURVEILLANCE
RECORD OF POSITIVE CULTURE.
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MOTIVATING THE STAFF.NEONATAL TRANSPORT
INDICATIONS
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BEST transport method: in-utero transport
Monitoring during transportation
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ComplicationsINDICATIONS
Need for higher care
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Need for high frequencyNeed for iNO
Need for ECMO
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Need for hypothermia/whole body cooling/head cooling
Need for cardiac procedure
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Lack of NICU bed/expertee/equipmentPREPARE FOR TRANSPORT
Check ID, compare with mothers folder.
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IV fluids ( Neonatalyte)
History
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Reason for transferEscorts?
MONITORING
COMPLICATIONS
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HIGH RISK NEONATE:
COMPLICATIONS DURING TRANSPORT
Hypoxia
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Hypoglycaemia
Hypothermia
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HyperbilirumenaemiaHypovolaemia
Heavy sedation
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Infection
HISTORY OF REGIONALIZED TRANSPORT
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Medical transports date back as early as Ceasar? First transport isolette (1893)
? Newborn inter-hospital transport--9's
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? Chicago Dept. of Health System--9's
? Assisted ventilation on transport--9's France
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? Modern transport--97's Usher, CanadaROTCH-PUTNAM INCUBATOR(CIRCA 1893)
THE OBSTETRICAL BAG TRANSPORT
INCUBATOR (1922)
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DE LEE & WELDE TRANSPORTINCUBATORS 9'S)
NOVEL THERAPIES & EQUIPMENT: AVAILABLE DURING
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TRANSPORTELBW (surfactant, thermoregulation)
? Inhaled Nitric Oxide
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? ECMO
? Ventilators (HFOV)
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? Brain CoolingMRI Transport Incubator
? Capnography
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? Wireless internet and more
? Telemedicine (consults, ECHO, U/S)
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? Cong. Heart defects/transport to Cath labECMO: ON TRANSPORT
ECLS started at referring hospital
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? Time is of the essence? Must weigh benefit vs. risks and costs
? Team to include surgeons, neonatologists,
perfusionists, RRT 's, ECMO nurses
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? Need to be equipped, self-sufficient for 24h
? Cornish (Wilford Hall Air Force Base) first to use
portable ECMO on isolette (1987 & 1991) C-9 aircraft
? Now 16 year military experience (Wilson, Pediatrics,
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2002)HIGH FREQUENCY VENTILATION DURING TRANSPORT
. To treat severe RDS/ ARDS
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? Minimizes barotrauma? Uses low TV & high rates
? NICU units NOT portable
? Transport models being developed & tested
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MCQS: INFECTION CONTROLTo perform hand hygiene activity, the minimal time
needed using alcohol based handrub is
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10 Secb) 20 Sec
c) 30 sec
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d) 40 sec
To perform hand hygiene activity, the minimal time
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needed using soap and water is10 Sec
b) 20 Sec
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c) 30 sec
d) 40 sec
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How many moments for hand hygiene exist accordingto WHO
a)4
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b) 5 c) 6 d) 7
What is the most frequent source responsible for health
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care-associated infections?a) The hospital's water syste ) The hospital air
c) Germs already present on or within the patient d)
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The hospital environmentWhich of the following require hand hygiene actions
(hand rub/hand washing)?
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Before touching a patient Y / No
Immediately after body fluid exposure
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Yes /No
After exposure to the immediate surroundings of a
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patientYe s / No
Immediately before a clean/aseptic procedure
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Ye s / No
After touching a patient
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Ye s / No