Download WBUHS MBBS First Year 2019 July Biochemistry Paper II Question Paper

FirstRanker.com

001/19

The West Bengal University of Health Sciences

--- Content provided by‍ FirstRanker.com ---

Subject: Biochemistry
Paper: II

Full Marks: 50
Time: 2 ½ hours

--- Content provided by‌ FirstRanker.com ---

Attempt all questions. The figures in the margin indicate full marks.

Group A

1. a) Write with the help of a diagram, describe the stage of initiation and elongation of translation process in E. coli. State the mechanism of Streptomycin and Puromycin in the inhibition of translation process in prokaryotes. 9+3
   or
   b) Write down with the help of a diagram stage of initiation and elongation of replication process. Differentiate between DNA polymerase I and DNA Polymerase III. 3+9

--- Content provided by⁠ FirstRanker.com ---

Group B

2. Answer any two of the following:
   1. Write down the non-oxidative process of HMP Shunt Pathway and its importance. 6+1
   2. Write down the ß-oxidation of Palmitic acid and mention problem that arise out of medium chain Acyl CoA Dehydrogenase deficiency. 6+1
   3. Write down the synthesis of bilirubin. Explain the term direct bilirubin, indirect bilirubin and Van der Berg reagent. Mention the changes that take place in serum bilirubin (direct) and bilirubin (indirect) level in haemolytic and obstructive jaundice. 4+2+1

--- Content provided by⁠ FirstRanker.com ---

Group C

3. Write short note on any four: 4x3
   1. Cyt P450.
   2. Point mutation.
   3. Pyruvate dehydrogenase.
   4. Alkaptonuria.

   --- Content provided by FirstRanker.com ---

   5. Genome of retrovirus.

Group D

4. Explain the following statement: 4x3
   1. Hartnup disease gives rise to Pellagra like syndrome.
   2. Vitamin K deficiency is responsible for haemorrhagic diseases of newborn.

   --- Content provided by​ FirstRanker.com ---

   3. HDL participates in reverse cholesterol transport.
   4. RNA editing mechanism is responsible for APO B48 synthesis in intestinal cells.

FirstRanker.com

--- Content provided by‌ FirstRanker.com ---