The West Bengal University of Health Sciences
 MBBS 1st Professional Examination, July 2019 
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Subject: Physiology 
 Paper: I 
Full Marks: 50 
 Time: 2 ½ hours 
Attempt all questions. The figures in the margin indicate full marks.
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Group A
-  a) What are the different types of chemoreceptors regulating ventilation? How are they stimulated? List the pathways by which increased Pco2 stimulates ventilation. 3+4+5 
 or
 b) What are the two determinants of Cardiac Output? What do you understand by preload and afterload as applied to cardiac function? Mention the factors influencing them. What is ejection fraction? 2+4+4+2
Group B
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- Answer any two of the following: 2 X7 - Enumerate the muscle proteins. Explain briefly the sliding filament theory of muscle contraction. What is Rigor Mortis? 1+4+2
- How is oxygen transported in blood? Explain with a diagram the effect of PO2 on hemoglobin saturation. Comment on the effect of Carbon Monoxide on oxygen binding to hemoglobin. 2+3+2
- Draw a flow chart showing different stages of erythropoiesis with diagrammatic representation. Add a note on erythropoietin. 5+2
 
Group C
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- Write a brief account on any four: 4X3 - Salivary secretion.
- Rh incompatibility
- Presynaptic inhibition
- Pacemaker potential
- Gastro-colic reflex
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Group D
- Give the physiological explanation of the following: 4x3 - Hypoproteinemia causes edema.
- Tetanus can be demonstrated easily in a skeletal muscles.
- pH of urine rises after a heavy meal.
- Subendocardial region of the left ventricle is specially vulnerable to ischemia.
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