Download WBUHS MBBS First Year 2021 March Biochemistry Paper II Question Paper

The West Bengal University of Health Sciences

MBBS I Professional Examination (New Regulation), March 2021

Subject: Biochemistry

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Paper: II

Full Marks: 100

Time: 3 hours

Attempt all questions. The figures in the margin indicate full marks.

1. a) What is a balanced diet? What is the nutritional importance of dietary proteins? Discuss the protein-energy malnutrition with special reference to kwashiorkor disease. (3+6+6)
   

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   b) Explain the replication of a DNA molecule in the context of initiation, elongation and termination in prokaryotes with suitable diagrams. Enumerate the differences between DNA polymerase I, II & III. (10+5)
2. a) Expand the term PCR. Describe different steps for a PCR reaction. Enumerate any four uses of the PCR. (4+4+2)
   b) Describe the structural characteristics of an immunoglobulin molecule in general with a diagram. Explain the functional differences between T cell and B cell mediated immunity. (5+5)
   c) Enumerate the different modes of repair of DNA damage in humans. Explain the mechanism of any one of them with the disorder arising due to the defects on that pathway. (4+4+2)
3. Write short notes on the following: (2 x 5)
   

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   a) Tumour marker.
   b) Cell cycle.
4. Explain the following statements: (5 x 4)
   a) Macrophages show beneficial effects by generating free radicals.
   b) Endocrinal disorders may predispose to obesity.
   

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   c) Deficiency of ascorbic acid causes fragility of blood vessels.
   d) Under some conditions immunity causes damaging effects.
   e) Proto-oncogenes are regulatory genes.

P.T.O.

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