Case based scenario
HISTORY
Chief complaints:
- Breathlessness since 2 weeks
- Palpitations
- Central chest discomfort
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History of presenting illness:
- exacerbation of breathlessness since two weeks
- Insidious in onset
- Progressively increased to occur on minimal exertion.
- He has also had episodes of awakening from sleep due to breathlessness
- He has noticed palpitations which aggravates on walking and is associated with throbbing sensations.
- central chest discomfort on walking which is relieved on rest
- No history of cough, fever, loss of consciousness or swelling of feet or body.
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Past history:
- recurrent episodes of joint pains in his adolescence
- associated with fever
- Untreated
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- Since 4 years, he has noticed dyspnoea on heavy exertion.
- He had stopped manual labour 2 years ago but was able to carry on his daily routine activities.
- Since the past 4 months, he was not able to walk more than a kilometre without shortness of breath.
Provisional diagnosis:
Most likely a case of valvular heart disease due to rheumatic origin involving mitral or aortic valve.
EXAMINATION
General physical examination
- Patient is conscious, oriented to time place and person
- No pallor, icterus, cyanosis, clubbing, Lymphadenopathy or pedal edema.
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Vitals:
- Pulse: Rate- 80/min, regular rhythm, high volume, collapsing
- JVP: normal
- Blood pressure: 160/20 mmHg, right arm in supine position.
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CVS examination:
- Apex : is in left 6th ICS, anterior axillary line, hyperdynamic.
- No thrill.
- Auscultation:
- Aortic area- high pitched, blowing, early diastolic murmur of grade 3 radiating to the apex.
- Ejection systolic murmur grade 2 also heard.
- Other areas- normal sounds. R/S – normal. Abdomen- normal. CNS- Normal.
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- R/S examination- normal.
- Abdomen- normal.
- CNS- Normal.
Differential Diagnosis
- Thyrotoxicosis
- Aortic regurgitation
- Severe anemia
- Thiamine deficiency
- Sympathetic overdrive
- left heart failure
- Mitral stenosis
- Mitral regurgitation.
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INVESTIGATIONS
- General investigations
Complete blood count, DLC
ESR, CRP
Thyroid function tests
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Urinary thiamine excretion, blood thiamine levels
VDRL( for syphillitic aortitis)
ASO titres
Anti DNAse B
- investigation to rule out structural and functional heart defects.
Echocardiography- to diagnose the valvular dysfunction
Chest Xray
ECG
Cardiac catheterization.
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Diagnosis
- Chronic decompensated aortic regurgitation mostly Secondary to Rheumatic heart disease.
Management
- Asymptomatic patients with preserved ejection fraction are managed conservatively.
- Asymptomatic patients with reduced ejection fraction are managed surgically with aortic valve replacement.
- Symptomatic patients are managed with Aortic valve replacement.
- Management also depends on LV end ststolic and end diastolic diameter. (ESD> 50mm, EDD>65mm) are indication for aortic valve replacement.
- Patient undergoing any cardiac surgery is also considered for aortic valve replacement.
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