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Download MBBS (Bachelor of Medicine and Bachelor of Surgery) Case based scenario

This post was last modified on 07 August 2021

MBBS All Subjects Clinical Case Scenarios (Clinical Case Studies)


Case based scenario

HISTORY

Chief complaints:

  • Breathlessness since 2 weeks
  • Palpitations
  • Central chest discomfort
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History of presenting illness:

  • exacerbation of breathlessness since two weeks
  • Insidious in onset
  • Progressively increased to occur on minimal exertion.
  • He has also had episodes of awakening from sleep due to breathlessness
  • He has noticed palpitations which aggravates on walking and is associated with throbbing sensations.
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  • central chest discomfort on walking which is relieved on rest
  • No history of cough, fever, loss of consciousness or swelling of feet or body.

Past history:

  • recurrent episodes of joint pains in his adolescence
  • associated with fever
  • Untreated
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  • Since 4 years, he has noticed dyspnoea on heavy exertion.
  • He had stopped manual labour 2 years ago but was able to carry on his daily routine activities.
  • Since the past 4 months, he was not able to walk more than a kilometre without shortness of breath.

Provisional diagnosis:

Most likely a case of valvular heart disease due to rheumatic origin involving mitral or aortic valve.

EXAMINATION

General physical examination

  • Patient is conscious, oriented to time place and person
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  • No pallor, icterus, cyanosis, clubbing, Lymphadenopathy or pedal edema.

Vitals:

  • Pulse: Rate- 80/min, regular rhythm, high volume, collapsing
  • JVP: normal
  • Blood pressure: 160/20 mmHg, right arm in supine position.
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CVS examination:

  • Apex : is in left 6th ICS, anterior axillary line, hyperdynamic.
  • No thrill.
  • Auscultation:
    • Aortic area- high pitched, blowing, early diastolic murmur of grade 3 radiating to the apex.
    • Ejection systolic murmur grade 2 also heard.
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    • Other areas- normal sounds. R/S – normal. Abdomen- normal. CNS- Normal.
  • R/S examination- normal.
  • Abdomen- normal.
  • CNS- Normal.

Differential Diagnosis

  • Thyrotoxicosis
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  • Aortic regurgitation
  • Severe anemia
  • Thiamine deficiency
  • Sympathetic overdrive
  • left heart failure
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  • Mitral stenosis
  • Mitral regurgitation.

INVESTIGATIONS

  1. General investigations

    Complete blood count, DLC

    ESR, CRP

    Thyroid function tests

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    Urinary thiamine excretion, blood thiamine levels

    VDRL( for syphillitic aortitis)

    ASO titres

    Anti DNAse B

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  3. investigation to rule out structural and functional heart defects.

    Echocardiography- to diagnose the valvular dysfunction

    Chest Xray

    ECG

    Cardiac catheterization.

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Diagnosis

  • Chronic decompensated aortic regurgitation mostly Secondary to Rheumatic heart disease.

Management

  • Asymptomatic patients with preserved ejection fraction are managed conservatively.
  • Asymptomatic patients with reduced ejection fraction are managed surgically with aortic valve replacement.
  • Symptomatic patients are managed with Aortic valve replacement.
  • Management also depends on LV end ststolic and end diastolic diameter. (ESD> 50mm, EDD>65mm) are indication for aortic valve replacement.
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  • Patient undergoing any cardiac surgery is also considered for aortic valve replacement.

Thank you

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