Download PTU M-Pharma 2019 May 2nd Semester 74926 MODERN BIO ANALYTICAL TECHNIQUES Question Paper

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Total No. of Pages : 01

Total No. of Questions : 06

M.Pharmacy(Pharmaceutical Analysis) (2017 Batch) (Sem.-2)

MODERN BIO- ANALYTICAL TECHNIQUES

Subject Code : MPA-202T

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M.Code: 74926

Time: 3 Hrs.

Max. Marks: 75

INSTRUCTIONS TO CANDIDATES :

1. Attempt any FIVE questions out of SIX questions.

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2. Each question carries FIFTEEN marks.

1. A. Principles and procedure of Liquid-Liquid extraction. 5
   B. General principle and procedure involved in Protein Precipitation. 5
   C. Purpose of bioavailability studies. 5
2. A. Discuss biopharmaceutical factors affecting drug bioavailability. 8
   

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   B. Write a note on cytochrome-P450 based drug interactions. 7
3. A. Describe In-vitro assay of drug metabolites and drug metabolizing enzymes. 8
   B. Discuss principle and application of cell viability assays. 7
4. A. Describe design and evaluation of bioequivalence studies for drug product performance. 8
   B. Discuss in details principle and procedure involved in solid phase extraction. 7

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5. Write notes on:
   A. Basic equipments used in cell culture lab. 5
   B. Biosimilar products 5
   C. Regulatory perspectives of metabolite identification 5
6. A. Discuss Principles and applications of flow cytometry. 10
   

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   B. What are microsomal approaches in metabolite identification? 5

NOTE : Disclosure of Identity by writing Mobile No. or Making of passing request on any page of Answer Sheet will lead to UMC against the Student.

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