Roll No.
Total No. of Questions : 06
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Total No. of Pages : 01
M.Pharmacy(Pharmacology) (2017 Batch) (Sem.-2)
PHARMACOLOGICAL & TOXICOLOGICAL SCREENING METHODS-II
Subject Code : MPL-202T
M.Code: 74944
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Time: 3 Hrs.
Max. Marks: 75
INSTRUCTIONS TO CANDIDATES :
- Attempt any FIVE questions out of SIX questions.
- Each question carries FIFTEEN marks.
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Q.1 Write an extensive note on acute and sub-acute toxicity testing as per OECD guidelines with suitable examples and/or flow charts. (15)
Q.2 a. Discuss the origin, concepts and importance of safety pharmacology. (8)
b. Elaborate on Tier 1 studies with specific focus on CNS. (7)
Q.3 a. Write a note on alternative methods to animal toxicity testing. (5)
b. Discuss the concept of toxicokinetics with suitable examples. (5)
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c. Describe Ames test. (5)
Q.4 Give a detailed account on ICH guidelines for conducting regulatory toxicity studies. (15)
Q.5 Write short notes on the following:
a. Teratogenicity studies (7)
b. IND enabling studies (8)
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Q.6 Discuss the following with suitable examples :
a. Eye irritation study (5)
b. Male reproductive toxicity testing (5)
c. HERG assay (5)
NOTE : Disclosure of Identity by writing Mobile No. or Making of passing request on any page of Answer Sheet will lead to UMC against the Student.
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This download link is referred from the post: PTU M.Pharm (Master of Pharmacy) 2nd Semester Last 10 Years 2010-2020 Previous Question Papers|| Punjab Technical University
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