Download PTU (Punjab Technical University) M-Pharma (Master of Pharmacy) 2nd Semester 74944 PHARMACOLOGICAL and TOXICOLOGICAL SCREENING METHODS II Last 10 Years 2020, 2019, 2018, 2017, 2016, 2015, 2014, 2013, 2012, 2011 and 2010 Previous Question Papers.
Roll No. Total No. of Pages : 01
Total No. of Questions : 06
M.Pharmacy(Pharmacology) (2017 Batch) (Sem.?2)
PHARMACOLOGICAL & TOXICOLOGICAL SCREENING
METHODS-II
Subject Code : MPL-202T
M.Code : 74944
Time : 3 Hrs. Max. Marks: 75
INSTRUCTIONS TO CANDIDATES :
1. Attempt any FIVE questions out of SIX questions.
2. Each question carries FIFTEEN marks.
Q.1 Write an extensive note on acute and sub-acute toxicity testing as per OECD guidelines
with suitable examples and/or flow charts. 15
Q.2 a. Discuss the origin, concepts and importance of safety pharmacology. 8
b. Elaborate on Tier 1 studies with specific focus on CNS. 7
Q.3 a. Write a note on alternative methods to animal toxicity testing. 5
b. Discuss the concept of toxicokinetics with suitable examples. 5
c. Describe Ames test. 5
Q.4 Give a detailed account on ICH guidelines for conducting regulatory toxicity studies. 15
Q.5 Write short notes on the following :
a. Teratogenicity studies 7
b. IND enabling studies 8
Q.6 Discuss the following with suitable examples :
a. Eye irritation study 5
b. Male reproductive toxicity testing 5
c. HERG assay 5
NOTE : Disclosure of Identity by writing Mobile No. or Making of passing request on any
page of Answer Sheet will lead to UMC against the Student.
FirstRanker.com - FirstRanker's Choice
This post was last modified on 07 December 2019