Roll No.
Total No. of Questions : 06
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Total No. of Pages : 01
M.Pharmacy (Pharmaceutics) (2017 Batch) (Sem.-2)
MOLECULAR PHARMACEUTICS
(NANO TECH AND TARGETED DDS)
Subject Code : MPH-201
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M.Code: 74961
Time: 3 Hrs.
Max. Marks: 75
INSTRUCTIONS TO CANDIDATES :
- Attempt any FIVE questions out of SIX questions.
- Each question carry FIFTEEN marks.
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Q1. (a) What are Aptamers? Give their applications. 3
(b) What is EPR? 3
(c) Enumerate six diseases heated by gene therapy. 3
(d) Explain methods used for filling of aerosols. 3
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(e) Define Aquasomes. 3
Q2. (a) Discuss various viral carrier systems used in gene delivery. 10
(b) Define somatic gene therapy. Discuss different types of somatic gene therapy. 5
Q3. (a) Discuss methods facilitating nasal absorption. 7
(b) Explain quality control tests of aerosol formulations. 8
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Q4. (a) Discuss various polymers used in the preparation of nanoparticles. 10
(b) Discuss the sterility aspects of liposomes. 5
Q5. (a) Explain the importance of cellular and lymphatic uptake in targeted drug delivery systems. 10
(b) Discuss the factors affecting drug transport across blood brain barrier. 5
Q6. (a) What are microspheres? Explain in detail methods of preparation and applications in drug delivery systems. 10
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(b) Discuss various components and their role in formation of niosomes. 5
NOTE : Disclosure of Identity by writing Mobile No. or Making of passing request on any page of Answer Sheet will lead to UMC against the Student.
1| M-74961
(S31)-355
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