? It is quantitatively large and highly
selective
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? It includes both active and passive
mechanisms
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? Primary active transport? Secondary active transport
Substances actively reabsorbed
and follow transport maximum
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? Glucose
? Phosphates
? Sulfate
? Amino acids
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? Urate? Lactate
? Plasma proteins
Substances actively secreted
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and follow transport maximum? Creatinine
? Para-amino Hippuric Acid (PAH)
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? PCT secretes? Bile acids
- Oxalate
- Urate
- Catecholamines
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Clearance tests to quantify renal
function
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? Clearance rate (C S) = U S ? V/ PS
? GFR = Uinulin ? V/ Pinulin
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? Clearance ratio = C S/ Cinulin? ERPF = CPAH
? RBF = RPF/ 1 ? Hematocrit
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? Excretion rate = US ? V