What is lymph ?
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Tissue fluid (interstitial fluid) that enters thelymphatic vessels
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Formation and transport of tissue fluidLymphatic system
Essentially a drainage
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system accessory to
venous system
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larger particles that escape intotissue fluid can only be removed
via lymphatic system
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Functions?Network that filters antigens from the interstitial fluid
?Primary site of immune response from tissue antigens
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?Lymphatic drainage in al organs of the body except brain, eyes, marrow
and cartilage
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?Flaccid thin wal ed channels progressive caliber?600 lymph nodes in body
?Slow flow, low pressure system returns interstitial fluid to the blood system
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Components of lymphatics
? Lymph
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? Lymphatic Vessels? Lymphatic Organs
? Lymphatic cells
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Secondary lymphoid tissue
Lymphatic Capil aries
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24-
8Features of structure:
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Blind endSingle layer of overlapping endothelial
cells
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More permeable than that of bloodcapillary
Absent from avascular structures, brain,
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spinal cord splenic pulp and bone
marrow
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Lymphatic Vessels
24-
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9?Three layered wall but thinner
than vein
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?More numerous valves than
in vein
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?Interposed by lymph nodes atintervals
?Arranged in superficial and
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deep sets
Lymph Trunks
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? Right and left jugular trunks? Right and left subclavian trunks
? Right and left bronchomediastinal trunks
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? Right and left lumbar trunks
? Intestinal trunk
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Lymphatic Ducts
Right lymphatic duct
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Thoracic ductLymphatic Cel s
24-
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12 Also called lymphoid cells
Located in both the lymphatic system and the cardiovascular
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system.Work together to elicit an immune response.
Types of lymphatic cells are:
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? Macrophages? Epithelial cells
? Dendritic cells
? Lymphocytes
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Lymphatic Organs
Primary organs
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?Red bone marrow?Thymus gland
Secondary organs
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?Lymph nodes
?Lymph nodules
?Spleen
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Lymph nodesCapsular shel
Fibroblasts and reticulin
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fibersMacrophages
Dendritic cel s
T cel s
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Head & Neck NodesAxil ary Nodes
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Inguinal Lymph nodes
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LymphangitisInflammation of the lymph vessels
Commonest cause bacteria called streptococcus
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pyogenes(most common).
Lymph vessels appear as red streaks through the
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FilariasisLymphedema
Occurs due to accumulation of
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lymphatic fluid in the interstitial
tissue
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Sometimes can be appreciatedafter wearing tight clothing or
jewellary on affected limb
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Lymphadenopathy
Means a disease of the
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lymph nodes
Lymph nodes become
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swollen/ enlarged andmay be painful to touch
Lymphomas
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Cancers originating either
from the lymphocytes in the
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lymph nodes or thelymphatic tissue in organs
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Tonsil itisInfection of the pharyngeal
tonsils
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Tonsils are swollen,
Fever and pain during
swallowing usually present
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