Appendix lumen obstruction leads to congestion within the appendix
Inflammatory exudate and mucous increases luminal pressure
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Initial stage might resolve in some patients
Appendix may distend with mucus- mucocele
APPENDICITIS COMPLICATIONS
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Gangrenous Appendicitis:
Thrombosis of the appendiceal artery and veins
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Perforation:
complication rates 58 %
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perforation rate increased at both ends of the age spectrumPeri-appendiceal abscess:
most frequent complication
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peri-appendiceal fibrinous adhesions
Peritonitis:
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Bacterial peritonitis in absence of fibrinous adhesions.Escherichia coli
Bowel Obstruction
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Septic seeding of mesenteric vessels
infection along the mesenteric?portal venous system
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pylephlebitis, pylethrombosis, or hepatic abscessOBSTRUCTION
Mucus + Inflammatory exudation Increases intraluminal Pressure
Obstructing lymphatic drainage
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Edema+ M.Ulceration+ Bacterial Translocation to the submucosa
Venous obstruction( cos of further distension)
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Ischemia Bacterial Invasion Acute Appendicitis.PERFORATION
If Fever > 102*F & WBC> 18,000
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If Ischemia continue
Necrosis of the appendicular wall
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Gangrenous appendicitisPerforation with free bacterial contamination of the peritoneal cavity
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PERFORATED APPENDIXGANGRENOUS APPENDIX
Thrombosis of Appendicular artery
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(as it is an end artery)PHLEGMONOUS MASS/ PARACAECAL ABSCESS
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Greater omentum & loops of smal bowel become adherent to the inflamed appendixWal ing off the spread of peritoneal contamination
Phlegmonous Mass / Paracaecal abscess
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DESTRUCTIVE PHLEGMONOUS APPENDICITIS
Appendicular inflammation resolves
Distended mucus filled organ
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Mucocele of appendix
SYMPTOMS
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PainInitially periumbilical region
Pain shift to right iliac fossa
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Parietal peritoneum irritated and inflamed
Anorexia
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Nausea/ vomitingCLINICAL SIGN
Pyrexia: Low grade after 6 hours
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Tenderness (localized) in the RIFMuscle guarding
Rebound Tenderness/ BLUMBERG'S Sign
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Tachycardia: Perforation, Gangrene & Peritonitis
SIGN TO ELICIT APPENDICITIS
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Rovsing's SignPsoas Sign
Obturator Sign
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Dunphy's Sign: Any movement ( Coughing) causes Pain.
Mc Burney's Point -Tenderness
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INVESTIGATION
TLC- Raised: 10000 to 18000 ( Neutrophils >75%).
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If TLC >18000 (suspect perforation)Abdominal X-Ray
Abdominal Ultra sonography
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CT Scan
ALVARADO SCORING SYSTEM SYMPTOMS SCORE
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Score
Inference
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7-10Strongly predictive of appendicitis
5-6
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Equivocal
Radiological investigations
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1-4Appendicitis ruled out
TREATMENT
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Absolute bed rest & NPOIV Fluids Supplements
Analgesics
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Antibiotics
Appendectomy ( within 24 hours ASAP)
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INDICATIONS OF APPENDECTOMYAcute Appendicitis
Recurrent Appendicitis
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Mucocele of Appendix
Carcinoma
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INCISIONS IN APPENDECTOMY
COMPLICATION OF APPENDECTOMY
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Wound InfectionAdhesive Intestinal
Intra-abdominal abscess
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Obstruction
Ileus
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Faecal FistulaRespiratory complication like
Richter's Hernia
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pneumonia
DVT & Embolism
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Portal PyaemiaAPPENDICULAR LUMP
Appendix Edematous Caecum Terminal Ileum
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Loop of Intestine Omentum ( Greater Omentum)Adjacent Peritoneum Ascending Colon
PRESENTATION OF APPENDICULAR LUMP
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Usually on 3rd day of attack of appendicitis.
Lump in Right iliac Fossa
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Guarding over the lumpTenderness
Fever/ Increase pulse
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Appendicular Lump- Don't Operate (?)Severe adhesion/ Difficult to separate the part
Bloody and dangerous to operate
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Risk of Faecal fistula
Risk of iatrogenic injury
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OCHSNER- SHERREN REGIMENIst mark the size of the swel ing for further assessment
NPO & IV Fluid supplements
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Antibiotics, Analgesics
Temp, Pulse( 4 hourly) & Fluid record charting
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Al ow oral liquid on subsequent days.OCHSNER- SHERREN REGIMEN
If more vomiting- antiemetic &/+ PPI
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If size of the lump decreases ? continue the same.After 6-8 weeks = Interval Appendectomy (current literature does not support this view)
Prognosis: 90% success rate for this regimen.
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Failure to this regimen: suspect Crohn's & or Carcinoma
CRITERIA FOR STOPPAGE OF CONSERVATIVE TREATMENT IN
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APPEDICULAR LUMPRising pulse rate
Rising temperature
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Increasing or spreading abdominal pain
Increasing size of mass
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Vomiting or copious gastric aspirate