Download MBBS Physiology Presentations 17 Synapse Lecture Notes

Download MBBS (Bachelor of Medicine, Bachelor of Surgery) 1st Year, 2nd Year, 3rd Year and Final year Physiology 17 Synapse PPT-Powerpoint Presentations and lecture notes

Synapse

Synaptic transmission

Otto Loewi 1926


Synapse Types

? Anatomical
Axodendritic, axosomatic, axoaxonic
? Physiological
Electrical, chemical
? Functional
Excitatory, inhibitory, modulatory

Electrical vs Chemical Synapse


Vesicle recycling




Synaptic

vesicle

Mechanism of NT release




Endocytosis (vesicle formation)

Post Synaptic Potential
? EPSP
? IPSP


Fate of Neurotransmitter

? Enzymatic

degradation

? Glial cell uptake
? Diffussion
? Presynaptic

uptake

Properties

? Delay

? One way conduction

? Summation- temporal / spatial

? Facilitation

? Occulusion

? Synaptic inhibition ?

presynaptic,

postynaptic

feedback (renshaw cel )

feedforward
Synaptic

plasticity

Potentiatio

n

Depression

Short term

Long Term

Short Term

Long Term

augmentati

Post Tetanic

Habituatio

on

Potentiation

LTP

n

LTD