Otto Loewi 1926
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Synapse Types? Anatomical
Axodendritic, axosomatic, axoaxonic
? Physiological
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Electrical, chemical? Functional
Excitatory, inhibitory, modulatory
Electrical vs Chemical Synapse
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Vesicle recycling
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Synaptic
vesicle
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Mechanism of NT release
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Endocytosis (vesicle formation)
Post Synaptic Potential
? EPSP
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? IPSPFate of Neurotransmitter
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? Enzymaticdegradation
? Glial cell uptake
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? Diffussion? Presynaptic
uptake
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Properties? Delay
? One way conduction
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? Summation- temporal / spatial
? Facilitation
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? Occulusion? Synaptic inhibition ?
presynaptic,
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postynaptic
feedback (renshaw cel )
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feedforwardSynaptic
plasticity
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Potentiation
Depression
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Short term
Long Term
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Short TermLong Term
augmentati
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Post Tetanic
Habituatio
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onPotentiation
LTP
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n
LTD
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