Download MBBS Physiology Presentations 40 General Physiology Lecture Notes

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Mechanistic

WHY?

HOW?

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Physiology is closely related to

Anatomy
Syllabus for General Physiology ?)

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?Homeostasis
?Body fluids
?Structure and function of cell
?Transport across membrane

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?Membrane potentials

Functional levels of organization

* Chemical or molecular level

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* Cellular level

* Tissue level

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* Organ level

* Body system level

* Whole body level

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Transition

unicellular organism multicellular organism

Multiplication

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Differentiation

Typical cell & variation

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Structure :- Limiting membranes

Cell Organelles ? membrane bound

- without membrane

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Structure & functions of Organel es


Golgi apparatus

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Functions of cel as a whole
?Obtaining O2 & nutrients from environment
?Performing chemical reactions
?Elimination of waste products
?Synthesis of proteins for structure, growth

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?Controlling exchange of material
?Intracellular movement of materials
?Sensitiveness &response to environment
?Reproducing

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Other functions

Pinocytosis

-Endocytosis

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Receptor mediated
Phagocytosis

- Exocytosis

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- Intercellular junctions

Tight junctions

Gap junctions

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Desmosomes


-Movement of cilia ,flagella

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ECF

Importance in ECF & ICF composition

ICF

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Intercel ular communication

Paracrine

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Endocrine

Neurocrine

Intercel ular communication

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transport of substances across

the cel membrane

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Methods of transport

Passive

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Active

-Diffusion

Osmosis Filtration

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Simple

facilitated

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?Lipid

bilayer

?Protein

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Leaky channels

voltage gated

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channels

Gated channels

Ligand gated

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Active transport

?Primary active transport
?Secondary active transport

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Types of transporters

Uniport

Synport

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Antiport

Substances transported for

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chemical reactions

electrical

potentials at the

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membrane
Body fluid compartments- 60% of body wt.

ICF-2/3

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ECF ? 1/3

Interstitial fluid

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plasma Transcellular

Measured by dye dilution method
Term used for describing conc. Of

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solutions in Physiology

Molarity & Normality (equivalent)

Osmolarity and tonicity

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pH & buffers

Terms used in homeostasis

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Milieu Interior
Parameters
Role of each system
controlled

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negative

Mechanisms involved-

positive

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Feedback mechanisms
Feed forward mechanisms
Gain , limitations