Download MBBS Physiology Presentations 40 General Physiology Lecture Notes

Download MBBS (Bachelor of Medicine, Bachelor of Surgery) 1st Year, 2nd Year, 3rd Year and Final year Physiology 40 General Physiology PPT-Powerpoint Presentations and lecture notes

2 approaches to study Physiology

Teleological

Mechanistic

WHY?

HOW?

Physiology is closely related to

Anatomy
Syllabus for General Physiology ?)

?Homeostasis
?Body fluids
?Structure and function of cell
?Transport across membrane
?Membrane potentials

Functional levels of organization

* Chemical or molecular level

* Cellular level

* Tissue level

* Organ level

* Body system level

* Whole body level
Transition

unicellular organism multicellular organism

Multiplication

Differentiation

Typical cell & variation

Structure :- Limiting membranes

Cell Organelles ? membrane bound

- without membrane

Structure & functions of Organel es


Golgi apparatus
Functions of cel as a whole
?Obtaining O2 & nutrients from environment
?Performing chemical reactions
?Elimination of waste products
?Synthesis of proteins for structure, growth
?Controlling exchange of material
?Intracellular movement of materials
?Sensitiveness &response to environment
?Reproducing

Other functions

Pinocytosis

-Endocytosis

Receptor mediated
Phagocytosis

- Exocytosis
- Intercellular junctions

Tight junctions

Gap junctions

Desmosomes


-Movement of cilia ,flagella
ECF

Importance in ECF & ICF composition

ICF

Intercel ular communication

Paracrine

Endocrine

Neurocrine

Intercel ular communication

transport of substances across

the cel membrane


Methods of transport

Passive

Active

-Diffusion

Osmosis Filtration

Simple

facilitated

?Lipid

bilayer

?Protein

Leaky channels

voltage gated

channels

Gated channels

Ligand gated
Active transport

?Primary active transport
?Secondary active transport

Types of transporters

Uniport

Synport

Antiport

Substances transported for

chemical reactions

electrical

potentials at the

membrane
Body fluid compartments- 60% of body wt.

ICF-2/3

ECF ? 1/3

Interstitial fluid

plasma Transcellular

Measured by dye dilution method
Term used for describing conc. Of

solutions in Physiology

Molarity & Normality (equivalent)

Osmolarity and tonicity

pH & buffers

Terms used in homeostasis

Milieu Interior
Parameters
Role of each system
controlled

negative

Mechanisms involved-

positive

Feedback mechanisms
Feed forward mechanisms
Gain , limitations