Download RGUHS (Rajiv Gandhi University of Health Sciences ) Ph.D Entrance Examination (Doctor of Philosophy) 2020 March P002 Pharmaceutical Chemistry Paper II Previous Question Paper
Rajiv Gandhi University of Health Sciences, Karnataka
Ph.D Entrance Examination ? 06-Mar-2020
[Time: 90 Minutes]
[Max. Marks: 50 Marks]
FACULTY: PHARMACY
SUBJECT: PHARMACEUTICAL CHEMISTRY
PAPER ? II
Q.P. CODE: P002
Your answers should be specific to the Questions asked.
Answer All The Questions
10 X 05 = 50 Marks
1.
Explain the structure and stability of carbocations.
2.
Discuss the therapeutic applications of Vitamin B1, Vitamin B2 and Folic acid.
3.
With suitable examples, explain the mechanism of action of Alkylating agents and
antimetabolites as antineoplastic agents.
4.
Suggest the mechanism involved in Beckmann's rearrangements and Aldol condensation.
5.
Discuss the concept of green chemistry with suitable examples.
6.
Discuss the retro synthesis with suitable example in medicinal chemistry.
7.
Enumerate the adrenal cortex hormones with their therapeutic applications.
8.
Discuss the applications of microbial transformations with relevant examples.
9.
Write the structure and therapeutic applications of mutual prodrug `Amoxycillin and Clavulanic
acid''.
10. Explain the concept of `bioisosterism' and its applications in the drug discovery.
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This post was last modified on 08 June 2022