Download RGUHS PHD Entrance Examination P002 Pharmaceutical Chemistry Paper II 2019 March Question Paper

Download RGUHS (Rajiv Gandhi University of Health Sciences ) Ph.D Entrance Examination (Doctor of Philosophy) 2019 March P002 Pharmaceutical Chemistry Paper II Previous Question Paper

Rajiv Gandhi University of Health Sciences

Ph.D Entrance Examination ? MARCH-2019

[Time: 90 Minutes]

[Max. Marks: 50 Marks]

Faculty : Pharmacy

Subject : Pharmaceutical Chemistry

PAPER ? II

Q.P. CODE: P002

Your answers should be specific to the Questions asked.

Answer All The Questions

10 X 05 = 50 Marks

1.

Explain various physiochemical parameters in QSAR with special reference to electronic and
hydrophobic parameters.

2.

Suggest the mechanisms involved in the following:
i. Pyrrole to 3-Chloropyridine
ii. Pinacole-Pinacolone rearrangement

3.

With suitable examples, explain the mechanism of action of plant products uses as
antineoplastic agents.

4.

Explain receptor binding assays with suitable examples.

5.

Explain the design and development of proton pump inhibitors.

6.

Explain the role of immunostimulants and immunosuppressants.

7.

Enumerate the third generation cephalosporins with their therapeutic applications.

8.

Explain the principles of green chemistry. Add a note on the applications microwave irradiation
techniques.

9.

Explain disconnection approach with suitable examples.

10.

Explain the design and development of anyone enzyme inhibitor.

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