[Max. Marks: 50 Marks]
Faculty : Pharmacy
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Subject : Pharmaceutical Chemistry
PAPER ? II
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Q.P. CODE: P002Your answers should be specific to the Questions asked.
Answer All The Questions
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10 X 05 = 50 Marks
1.
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Explain various physiochemical parameters in QSAR with special reference to electronic andhydrophobic parameters.
2.
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Suggest the mechanisms involved in the following:i. Pyrrole to 3-Chloropyridine
ii. Pinacole-Pinacolone rearrangement
3.
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With suitable examples, explain the mechanism of action of plant products uses as
antineoplastic agents.
4.
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Explain receptor binding assays with suitable examples.
5.
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Explain the design and development of proton pump inhibitors.6.
Explain the role of immunostimulants and immunosuppressants.
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7.
Enumerate the third generation cephalosporins with their therapeutic applications.
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8.Explain the principles of green chemistry. Add a note on the applications microwave irradiation
techniques.
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9.Explain disconnection approach with suitable examples.
10.
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Explain the design and development of anyone enzyme inhibitor.
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Document Outline
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