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UNIVERSITY OF JAFFNA, SRI LANKA
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BACHELOR OF PHARMACY
FOURTH YEAR FIRST SEMESTER EXAMINATION – JANUARY 2016
PHANP 4104 NATURAL PRODUCT CHEMISTRY - PAPER II
Date: 27.01.2016 Time: 2 Hours
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Answer all Six questions.
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- Classify the naturally occurring purines. (20 Marks)
- How can you confirm the position of oxygen atom at C6 position in caffeine? (40 Marks)
- Indicate how theophylline could be synthesized from uric acid? (40 Marks)
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- List the active compounds in adrenal cortex extract. (30 Marks)
- Draw the chemical structures for the following compounds. (30 Marks)
- Prednisolone
- Beclomethasone
- Hydrocortisone
- Show how do you synthesize testosterone by microbiological method? (40 Marks)
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- Give the basic structure of betalactum antibiotics. (20 Marks)
- Draw the structures of five naturally occurring Penicillins. (40Marks)
- Discuss the Structure Activity Relationship of Penicillins. (40 Marks)
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- Name the sugars and their linkage present in Streptomycin. (15 Marks)
- How will you detect the presence of nitro group in chloramphenicol? (20 Marks)
- Give the synthesis of Chloramphenicol starting from p-nitroacetophenone. (65 Marks)
- Write short notes on
- Diel's hydrocarbon. (30 Marks)
- Murexide reaction of uric acid. (30 Marks)
- Natural Oestrogens. (40 Marks)
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- List the natural bile acids. (20 Marks)
- How can you isolate bile acid from natural bile? (30 Marks)
- Draw the synthesis of progesterone from a sapogenin glycoside. (50 Marks)
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This download link is referred from the post: NTRUHS MBBS 2nd Year 2010-2025 Question Papers (Dr. NTR University of Health Sciences)
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