Download MBBS 1st Year 2002 March Biochemistry Paper II Question Paper

MARCH - 2002

Sub. Code: 4056

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FIRST M.B.B.S. DEGREE EXAMINATION.

(Non-Semester)

(Revised Regulations)

Paper VI - BIOCHEMISTRY - II

Time: Three hours

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Theory: Two and a half hours

M.C.Q.: Half an hour

Maximum: 100 marks

Theory: 70 marks

M.C.Q.: 30 marks

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MCQ must be answered separately on the answer sheet provided as per instructions on the first page.

1. Define the terms "Replication, transcription and translation". Describe the steps involved in protein biosynthesis.

   (15)

2. Write short notes on:

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   1. Maple syrup urine disease
   2. PRPP biosynthesis and its importance
   3. Chromatography
   4. Genetic code.

   (4 x 5 = 20)

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3. Write in detail diagrammatically the reaction mechanisms by which HCO₃^- is reclaimed and regenerated in kidneys. What is meant by metabolic acidosis and how it is compensated?

   (15)

4. Write short notes on:

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   1. Wilson's disease
   2. Structure and functions of Insulin
   3. Carcinogen
   4. Describe the "Southern Blot" technique. Enumerate two applications of the technique.

   (4 × 5 = 20)

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[KG 505 A]

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