MARCH - 2002
Sub. Code: 4056
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FIRST M.B.B.S. DEGREE EXAMINATION.
(Non-Semester)
(Revised Regulations)
Paper VI - BIOCHEMISTRY - II
Time: Three hours
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Theory: Two and a half hours
M.C.Q.: Half an hour
Maximum: 100 marks
Theory: 70 marks
M.C.Q.: 30 marks
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MCQ must be answered separately on the answer sheet provided as per instructions on the first page.
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Define the terms "Replication, transcription and translation". Describe the steps involved in protein biosynthesis.
(15)
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Write short notes on:
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- Maple syrup urine disease
- PRPP biosynthesis and its importance
- Chromatography
- Genetic code.
(4 x 5 = 20)
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Write in detail diagrammatically the reaction mechanisms by which HCO3- is reclaimed and regenerated in kidneys. What is meant by metabolic acidosis and how it is compensated?
(15)
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Write short notes on:
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- Wilson's disease
- Structure and functions of Insulin
- Carcinogen
- Describe the "Southern Blot" technique. Enumerate two applications of the technique.
(4 × 5 = 20)
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[KG 505 A]
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