(Non--Semester)
(Revised Regulations)
Paper V - BIOCHEMISTRY - I
Time: Three hours Maximum: 100 marks
Theory: Two hours and Theory: 80 marks
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forty minutes M.C.Q.: 20 marks
M.C.Q.: Twenty minutes
Draw labelled diagrams wherever necessary.
I. Essay: (2 x 15 = 30)
Answer ALL questions.
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- Write about the sources, activation, bio--chemical functions, deficiency disease and its detection of Thiamine.
- Write in detail about Glucose homeostasis in the human organism and add a note on its biomedical importance.
II. Write short notes on: (10 x 5 = 50)
- (a) Biochemical functions of Vitamin D.
- (b) Absorption of lipids.
- (c) Excretion of Bilirubin and clinical importance of Bilirubin estimations.
- (d) Coupling of oxidative phosphorylation, uncouplers and their importance.
- (e) Clinical importance of Isoenzymes with suitable examples.
- (f) Biochemical changes in Vongierke's disease and their relation to enzyme deficiency.
- (g) Role of LDL receptors in metabolism of low density lipoproteins and the disease caused by its defect.
- (h) Definition, expression and significance of Km value.
- (i) Role of liver in integration of metabolism during post prondial state.
- (j) Caloric requirement and it's recommended distribution among nutrients in an adult male.
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2 [KJ 504]
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