HEALTH SCIENCES
WARANGAL, TELANGANA STATE - 506 002
MBBS SECOND YEAR DEGREE
SUPPLEMENTARY EXAMINATIONS: JUNE,
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2025PATHOLOGY
Paper -I
Time: 3 Hours
Max. Marks: 100
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Note: Answer all questionsGive Diagrammatic representation wherever necessary
Multiple Choice Questions:
10 X 1 = 10
1) Epstein Barr virus causes all EXCEPT:
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a) Infectious Mononucleosisc) Burkitt's lymphoma
b) Nasopharyngeal carcinoma
d) Acute myeloid leukaemia
2) Interstitial pulmonary fibrosis can occur due to all
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except:a) Busulfan
c) Tetracycline
b) Nitrofurantoin
d) Bleomycin
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3) All of the following is true for anaemia of chronic
diseases except?
a) Low serum iron levels
c) Increased hepcidin
b) Low erythropoietin
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d) Low ferritin4) Defect in sickle cell disease is
a) Glutamate residue instead of a
valine residue at the 6th amino
acid position in (3-globin
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b) Valine residue instead of aglutamate residue at the 6th
amino acid position in 13-globin
c) Glutamate residue instead of a
valine residue at the 6th amino
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acid position in a -globind) Valine residue instead of a
glutamate residue at the 6th
amino acid position in a-globin
5) Hodgkin lymphoma with frequent mononuclear cells
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and classical ReedSternberg
a) Nodular sclerosis
c) Mixed cellularity
b) Lymphocyte depletion
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d) Lymphocyte predominance6) Idiopathic thrombocytopenic purpura is characterized
by:
a) Decreased platelet survival
c) Hypersplenism
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b) Decreased production ofplatelets
d) Dilutional thrombocytopenia
7) Bombay phenotype are the individuals who:
a) Lack H genes and therefore H
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substanceb) Possess A, B antigens
c) Secrete excessive amount of H
substance
d) Lack C, D and E antigens
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8) Cyclin dependent Kinases are all excepta) P57
b) P21
c) P53
d) P27
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9) Not a stain for Amyloid isa) Congo red
b) Methyl violet
c) Triphenyl tetrazolium chloride
d) Thioflavin T
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10) Not a cause of oedema isa) Increased hydrostatic pressure
c) Lymphatic obstruction
b) Increased plasma oncotic
pressure
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d) Sodium retentionEssay/ Long Answer Questions:
2 X 15-30
11. Define Apoptosis. Describe morphological features
and mechanism of Apoptosis. (2+6+7)
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12. Define and Classify of Leukaemia. Discuss theChromosomal abnormality and lab
findings in Chronic Myeloid Leukaemia. (2+3+4+6)
Short Answer Questions:
7 X 6=42
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13. Discuss about pathological Calcification.14. Describe Gaucher's Disease.
15. Von Willebrand's Disease.
16. Transplant rejection.
17. Factors affecting Wound Healing.
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18. Pathology of Vitamin D deficiency.19. Aplastic Anaemia.
Very Short Answer Questions:
6X3=18
20. Three types of Necrosis with examples.
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21. CSF findings in Pyogenic Meningitis.22. Three Opportunistic infections in HIV infection.
23. Morphology of Megaloblast.
24. Enumerate anticoagulants in Haematology.
25. Indications of Semen Analysis.
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