Download MPMSU MBBS 2nd Year Pharmacology Paper II June 2023 Question Paper

Madhya Pradesh Medical Science University, Jabalpur
MBBS Second Professional Examination June-2023
Subject- Pharmacology
Time: 3:00 Hours
Paper- II (old scheme)

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Maximum Marks :40

Instructions:
a) Al questions are compulsory
b) Draw diagrams wherever necessary

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c) Answers of Questions and Sub-questions must be written strictly according to serial order of question paper.
d) MCQ has to be answered in theory answer book
e) Please write MCQ answer neatly and in serial order with black or blue pen in brackets; for example: - 1. (a) 2. (c)
f)
MCQ has to be answered only once, any kind of repetition or cutting or erasing or whitener wil be considered as malpractice, such answers wil not be

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counted in marks and action wil be taken according to UFM rules of university.
g) Subjective answer should be answered in up to 30 words per marks. For example, if a question having 2 marks should answered in up to 60 marks.

Q1. Total MCQs: 16
16 x 1/2 = 8

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1. Fourth Generation cephalosporin is
(a) Cefepime
(b) Cefprozil
(c) Cefixime
(d) Cefadroxil

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2. Antagonist of Benzodiazepine is
(a) Naltrexone
(b) Flumazenil
(c) Naloxone
(d) N-Acetyl-cysteine

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3. Which of the fol owing drug can decrease the size of prostate
(a) Prazosin
(b) Sildenafil
(c) Finasteride
(d) Testosterone

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4. Cryptococcal Meningitis is treated with
(a) Griseofulvin
(b) Amphotericin B
(c) Posaconazole
(d) Caspofungin

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5. Dissociative anesthesia is seen on administration of:
(a) Ether
(b) Halothane
(c) Enflurane
(d) Ketamine

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6. Which of the fol owing drug is a SERM useful for treatment of osteoporosis?
(a) Raloxifene
(b) Bisphosphonate
(c) Letrozole
(d) Calcitonin

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7. Drug of choice for prophylaxis of Mania is:
(a) Clozapine
(b) Haloperidol
(c) Lithium
(d) Diazepam

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8. Total dose of chloroquine (250 mg Tablet) in Vivax malaria is:
(a) 4
(b) 6
(c) 8
(d) 10

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9. Tramadol is
(a) Anti-flatulent
(b) Anti-reflux drug
(c) Beta-Blocker
(d) Opioid analgesic

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10. Drug used as aversion therapy in Alcohol dependence is:
(a) Disulfiram
(b) Diazepam
(c) Propranolol
(d) Methadone

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11. Which neurotransmitter system is primarily targeted by tricyclic antidepressants (TCAs)?
(a) Dopamine
(b) Serotonin
(c) GABA
(d) Norepinephrine

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12. Which of the fol owing analgesic drugs is a selective cyclooxygenase-2 (COX-2) inhibitor?
(a) Ibuprofen
(b) Acetaminophen
(c) Celecoxib
(d) Morphine

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13. Which of the fol owing medications used in the treatment of gout works by increasing renal excretion of uric
acid?
(a) Colchicine
(b) Al opurinol
(c) Febuxostat

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(d) Probenecid
14. Which of the fol owing medications is a glucocorticoid receptor antagonist used for the treatment of Cushing's
syndrome?
(a) Insulin lispro
(b) Metoprolol

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(c) Mifepristone
(d) Pioglitazone
15. Which of the fol owing drugs is a nitroimidazole that is commonly used for the treatment of trichomoniasis and
giardiasis?
(a) Chloroquine

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(b) Metronidazole
(c) Atovaquone
(d) Mefloquine
16. Which storage temperatures is recommended for maintaining the stability and potency of most vaccines?
(a) -20 (-4?F)

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(b) 2-8?C (36-46?F)
(c) 15-25?C (59-77?F)
(d) 37?C (98.6?F)
Q2. Long Answer Questions
2 x 5 = 10

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a. Classify Antiepileptic drugs based on their Mechanism of Action. Write Uses and Adverse Effects of Phenytoin.
b. Classify first- and second-line drugs for tuberculosis. Describe and discuss al anti-tuberculosis drug regimens
recommended by RNTCP (2016).
Q3. Brief Answer Questions
4 x 3 = 12

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a. Write the advantages of Atypical Antipsychotics over Typical Antipsychotics.
b. Explain the pharmacological actions and therapeutic actions of aspirin at its different doses.
c. Explain the differences in the mechanisms of action between combined oral contraceptives (COCs) and
progestin-only contraceptives (POCs) in detail, including their effects on ovulation, cervical mucus, and
endometrium.

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d. Enumerate contraindications of corticosteroids. Discuss the adverse effects associated with long-term
glucocorticoid therapy and strategies to minimize these effects.
Q4. Short Answer Questions 10 x 1 = 10
a. Name Two Antipseudomonal Penicil ins.
b. Name Two drugs of different classes used in Open Angle Glaucoma.

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c. Write Two Contraindications of Morphine.
d. Enumerate drugs used in treatment of Thyroid Storm.
e. Name two drugs used as Local Anaesthetics.
f. Enumerate pre-anaesthetic medications with their role.
g. Explain the mechanisms of bacterial resistance to beta-lactam antibiotics.

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h. Enumerate the adverse effects and contraindications of lignocaine and adrenaline combination.
i. Enumerate shared toxicity of aminoglycoside antimicrobials.
j. Enumerate the advantages of combining levodopa and carbidopa.

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