Download MPMSU MBBS 2nd Year Pathology Paper I Apr 2024_01 Question Paper

Madhya Pradesh Medical Science University, Jabalpur
MBBS Second Professional Examination April-2024
Subject- Pathology
Paper- I (new scheme)
Time: 3:00 Hours

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Maximum Marks :100

Instructions:
a) Al questions are compulsory
b) Draw diagrams wherever necessary

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c) Answers of Questions and Sub-questions must be written strictly according to serial order of question paper.
d) MCQ has to be answered in theory answer book
e) Please write MCQ answer neatly and in serial order with black or blue pen in brackets; for example: - 1. (a) 2. (c)
f)
MCQ has to be answered only once, any kind of repetition or cutting or erasing or whitener wil be considered as malpractice, such answers wil not be

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counted in marks and action wil be taken according to UFM rules of university.
g) Subjective answer should be answered in up to 30 words per marks. For example, if a question having 2 marks should answered in up to 60 marks.

Q1. Total MCQs: 10
10 x 1 = 10

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1. Caseation necrosis occurs in
(a) Infective hepatitis
(b) Tuberculosis
(c) Amoebiasis
(d) Glomerulonephritis

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2. Eosinophilia occurs in
(a) Viral infections
(b) Fungal infections
(c) Acute pyogenic
(d) Parasitic infections

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infections
3. Healing by first intention requires
(a) Clean wounds
(b) Minimal loss of tissue
(c) No foreign bodies

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(d) Al of the above
4. Al of the fol owing are mediators of inflammation except-
(a) Tumor necrosis factor-
(b) Interleukin-1
(c) Myeloperoxidase

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(d) Prostaglandin
alpha
5. Vasoactive amine involved in inflammation is -
(a) Histamine
(b) Rennin

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(c) Angiotensin
(d) Endothelin
6. Zeihl Neelsen stain detects-
(a) Gram negative bacil i
(b) Gram positive bacil i

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(c) Acid fast bacil i
(d) Gram positive cocci
7. Factor VII deficiency causes-
(a) Hemophilia A
(b) Hemophilia B

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(c) Hemophilia c
(d) Hemophilia D
8. Iron absorption is increased by -
(a) Phytates
(b) Tannates

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(c) Plant food
(d) Ascorbic acid
9. True about apoptosis are al except-
(a) Inflammation is present (b) Chromosomal
(c) Clumping of chromatin (d) Cel shrinkage

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breakage
10. Morphologic changes in necrosis include
(a) Damage of cel
(b) Pyknosis
(c) Karyorrhexis

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(d) Al of the above
membrane

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Q2. Long Answer Questions
2 x 20 = 40

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a. A 20-year-old girl complains of weakness, easy fatigability and breathlessness of 6 months duration. She also
complains of heavy menstrual bleeding every month. On examination, she is pale and has spoon shaped
brittle nails and cheilosis.
I.
What is provisional diagnosis?

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II.
Discuss its etiopathogenesis.
III.
Describe the peripheral and bone marrow findings.
IV.

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Describe laboratory investigation.
b. A 55year old male patient presents with progressive fatigue, weight loss and edema in legs. Laboratory tests
reveal elevated levels of protein in urine, Congo red was used to diagnose it in abdominal fat aspirates.
Deposits in spleen show sago spleen and lardaceous spleen. On physical examination, he has hepatomegaly
and macroglossia.

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I. Identify the clinical condition
II.
What are its types and classification?
III.
What is its pathogenesis

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IV.
Systemic features on different organs
Q3. Brief Answer Questions
6 x 05 = 30
a. Define inflammation. Describe the vascular changes in acute inflammation.

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b. Define necrosis. Describe its types with suitable examples
c. Define and describe the pathogenesis of AIDS.
d. Difference between metastatic and dystrophic calcification
e. Define hypersensitivity reaction and its different types, with 1 example each
f. Define shock with pathogenesis of septic shock.

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Q4. Short Answer Questions
10 x 2 = 20
a. Virchow's triad
b. Paraneoplastic syndrome
c. Embolism

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d. Pancytopenia
e. Enumerate giant cel
f. Difference between intravascular and extravascular hemolysis
g. Enumerate factors that influences tissue repair
h. Enumerate 4 microscopic findings of granuloma

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i. Write differences between myeloblasts and lymphoblasts
j. Causes of chronic granulomatous inflammation

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