Download MPMSU MBBS 2nd Year Pathology Paper II Jan 2025 Question Paper

Madhya Pradesh Medical Science University, Jabalpur
MBBS Second Professional Examination January-2025
Subject- Pathology
Paper- II (new scheme)
Time: 3:00 Hours

--- Content provided by‍ FirstRanker.com ---

Maximum Marks :100

Instructions:
a) Al questions are compulsory
b) Draw diagrams wherever necessary

--- Content provided by‌ FirstRanker.com ---

c) Answers of Questions and Sub-questions must be written strictly according to serial order of question paper.
d) MCQ has to be answered in theory answer book
e) Please write MCQ answer neatly and in serial order with black or blue pen in brackets; for example: - 1. (a) 2. (c)
f)
MCQ has to be answered only once, any kind of repetition or cutting or erasing or whitener wil be considered as malpractice, such answers wil not be

--- Content provided by‍ FirstRanker.com ---

counted in marks and action wil be taken according to UFM rules of university.
g) Subjective answer should be answered in up to 30 words per marks. For example, if a question having 2 marks should answered in up to 60 marks.

Q1. Total MCQs: 10
10 x 1 = 10

--- Content provided by⁠ FirstRanker.com ---

1. Which virus is not transmitted parenteral y?
(a) Hepatitis B
(b) Hepatitis C
(c) Hepatitis G
(d) Hepatitis E

--- Content provided by​ FirstRanker.com ---

2. In which condition are Aschoff bodies seen?
(a) Rheumatoid arthritis
(b) Tuberculosis
(c) Rheumatic heart
(d) Sarcoidosis

--- Content provided by‌ FirstRanker.com ---

disease
3. The most common primary site for the origin of Paget's disease is:
(a) Nipple
(b) Anal canal
(c) Liver

--- Content provided by‌ FirstRanker.com ---

(d) Penis
4. Which of the fol owing is the most common cause of myocardial infarction?
(a) Hypertension
(b) Coronary artery
(c) Aortic stenosis

--- Content provided by FirstRanker.com ---

(d) Pulmonary embolism
thrombosis
5. In which of the fol owing conditions are Reed-Sternberg cells seen?
(a) Non-Hodgkin
(b) Hodgkin lymphoma

--- Content provided by⁠ FirstRanker.com ---

(c) Chronic lymphocytic
(d) Multiple myeloma
lymphoma
leukemia
6. Hypothyroidism is associated with al of the fol owing except:

--- Content provided by‌ FirstRanker.com ---

(a) Cretinism
(b) Autism
(c) Cold intolerance
(d) Weight gain
7. Not a germ cel tumor:

--- Content provided by FirstRanker.com ---

(a) Seminoma
(b) Yolk sac tumor
(c) PNET
(d) Dysgerminoma
8. Tamm-Horsfal protein is produced by:

--- Content provided by⁠ FirstRanker.com ---

(a) Distal tubules
(b) Ureter
(c) Loop of Henle
(d) Col ecting duct
9. Multiple sclerosis is an autoimmune disease that affects the:

--- Content provided by‍ FirstRanker.com ---

(a) Brain
(b) Spinal cord
(c) Peripheral nerves
(d) Muscles
10. Most common cause of Nephrotic syndrome in children is:

--- Content provided by‌ FirstRanker.com ---

(a) RPGN
(b) PSGN
(c) Minimal change disease (d) Focal GN

---

Q2. Long Answer Questions

--- Content provided by‍ FirstRanker.com ---

2 x 20 = 40
a. A 52-year-old woman presents with a palpable lump in her right breast. On examination, the lump is hard,
irregular, and fixed to the underlying tissue. There are palpable axil ary lymph nodes. A mammogram shows a
mass with micro calcifications. A biopsy is performed.
I.

--- Content provided by‌ FirstRanker.com ---

Based on the clinical presentation and imaging findings, what is the most likely histological diagnosis? (05
Mark)
II.
What are the key prognostic factors for breast carcinoma? (05 Mark)
III.

--- Content provided by FirstRanker.com ---

Describe the significance of immune histochemical staining in the diagnosis and prognosis of breast
carcinoma. (05 Mark)
IV.
What are the histological features of Paget's disease of the breast? (05 Mark)
b. A middle-aged known smoker presented with persistent cough with expectoration and evening raise in

--- Content provided by FirstRanker.com ---

temperature in the past two weeks. Chest x ray identified consolidation in the lower portion of the upper lobe
of right lung. Hilar lymphadenopathy was noted. Sputum examination detected acid fast bacil i.
I.
What is the most probable diagnosis? (5marks)
II.

--- Content provided by​ FirstRanker.com ---

Discuss the pathogenesis. (5marks)
III.
Describe the gross and microscopic findings (5 marks)
IV.
Mention two complications (5marks)

--- Content provided by‌ FirstRanker.com ---

Q3. Brief Answer Questions
6 x 05 = 30
a. What are the common causes of anemia, and how are they classified based on their morphology and
etiology?
b. Discuss the diagnostic pathologic criteria of rheumatic heart disease

--- Content provided by‍ FirstRanker.com ---

c. Enumerate the CSF findings in tuberculous meningitis
d. Describe in detail about melanoma?
e. How does hypertension lead to left ventricular hypertrophy?
f. Enlist the Classification of ovarian tumors
Q4. Short Answer Questions

--- Content provided by⁠ FirstRanker.com ---

10 x 2 = 20
a. Describe various types of giant cel s?
b. Paraneoplastic Syndrome
c. Enlist histopathological features of Papil ary of Carcinoma thyroid
d. Explain the characteristic renal histopathological finding in diabetic nephropathy and its clinical significance.

--- Content provided by FirstRanker.com ---

e. Mention four causes of Congenital Hyperbilirubinemia
f. Write the gene involved in retinoblastoma?
g. Enumerate HPV associated malignancies
h. Write al the parameters of complete blood count report (CBC)?
i. Write the battery of test for viral hepatitis?

--- Content provided by FirstRanker.com ---

j. Wilms Tumor

---