DR NTR UNIVERSITY OF HEALTH SCIENCES ::
VIJAYAWADA - 520 008
M.B.B.S. DEGREE EXAMINATION - FEBRUARY, 2019
SECOND M.B.B.S. EXAMINATION
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PATHOLOGY(GENERAL PATHOLOGY & HAEMATOLOGY)
PAPER-I
Time: 2 Hours
Max. Marks: 40
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Note: Answer all questionsDraw diagrammatic representation wherever
necessary
1) A 55 year old lady presented with progressive fatigue
and tiredness for
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last one month. She also complained of tingling andnumbness in the
lower limbs. On examination she had pallor and her
tongue had a glossy
appearance.
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a) What is your diagnosis?b) What is the cause for neurological symptoms in this
condition?
c) What are the peripheral smear and bone marrow
findings in this
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condition?d) Which specific tests would you like to do to diagnose
this
condition? 1+2+5+2=10
WRITE SHORT NOTES ON:
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5 x 4 = 202) Role of Rb gene in tumor suppression
3) Lab diagnosis of chronic myeloid leukemia
4) Pathogenesis of primary pulmonary tuberculosis
5) Morphology of lepromatous leprosy
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6) Role of vasoactive amines in acute inflammationWRITE BRIEFLY ON:
5 x 2 = 10
7) Fate of thrombus
8) Morphological changes in apoptosis
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9) Variants of Reed Sternberg cell10) Principle of Osmotic fragility test
11) List four clinical features of Klinefelter Syndrome
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