DR NTR UNIVERSITY OF HEALTH SCIENCES ::
VIJAYAWADA-8
M.B.B.S. DEGREE EXAMINATION - JANUARY, 2013
SECOND M.B.B.S. EXAMINATION
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PATHOLOGY(GENERAL PATHOLOGY & HAEMATOLOGY)
PAPER-I
Time: 2 Hours
Max. Marks: 40
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Note: Answer all questions. Give diagrammaticrepresentation wherever possible.
1) An young and stout male met with an accident. He
sustained multiple injuries, fractures of femur and tibia.
These fractures are stabilized at Surgery soon after
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admission. He is in a stable condition. However 2 daysafter admission he suddenly becomes dyspneic and
developed tachypnea and tachycardia, irritability,
restlessness and it progressed to delirium, coma and death
on 7th day.
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a) What is the provisional diagnosis?b) Discuss the pathogenesis of the lesion
c) Describe microscopic picture of the Lungs in the above
condition,
d) How "Frozen sections" of the lung tissue help in final
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diagnosis at autopsy and mention various stains specificfor it? 1+4+2+3 = 10
WRITE SHORT NOTES ON:
5 x 4 = 20
2) Protein derived mediators of acute inflammation.
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3) Down Syndrome4) Pathogenesis of Amyloidosis
5) Physical carcinogenesis
6) Blood and Bone marrow findings in Aplastic anemia.
WRITE BRIEFLY ON:
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5 x 2 = 107) Mention 4 sequelae of Ghon's complex
8) Name 4 main components of Extra cellular Matrix
(ECM)
9) Name 4 morphologic changes (cytoplasmic & Nuclear)
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in necrotic cell.10) Name 4 Blood components separated from whole
blood and mention one clinical use for each.
11) Mention 4 morphologic characteristics of a
Myeloblast.
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