DR NTR UNIVERSITY OF HEALTH SCIENCES ::
VIJAYAWADA - 8
M.B.B.S. DEGREE EXAMINATION - JULY, 2016
SECOND M.B.B.S. EXAMINATION
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PATHOLOGY(GENERAL PATHOLOGY & HAEMATOLOGY)
PAPER-1
Time: 2 Hours
Max. Marks: 40
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Note: Answer all questionsDraw neat diagram wherever necessary
1) A 20 year old male presented with swelling of both
knees and
pain for the past one week. He gives history of similar
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episodes earlier. He also gives history of excessivebleeding
after minor injuries. His maternal uncle has similar
complaints
and has been treated by repeated blood transfusions
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followingexcessive bleeding episodes.
a) What are the possible differential diagnoses?
b) What are the laboratory investigations required for the
diagnosis?
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c) What is the etiopathogenesis of theses disorders?d) How will you make the final specific diagnosis?
2+4+3+1=10
WRITE SHORT NOTES ON:
5 X 4 = 20
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5 X 4 = 20
2) Differences between benign and malignant tumors.
3) Bone marrow picture of megaloblastic anemia
4) Systemic thromboembolism
5) Leukemoid reaction
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6) Morphologic changes in KwashiorkorWRITE BRIEFLY ON:
5 X 2 = 10
7) Name four types of necrosis with one example each
8) Name four clinical features of trisomy 21
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9) Name four inherited cancer syndromes10) Name four subtypes of Hodgkin disease
11) Give four examples of type II hypersensitivity
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