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Code No: BP103T PCI SET -1
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I B. Pharmacy I Semester Regular/Supplementary Examinations, February - 2020PHARMACEUTICS-I
Time: 3 hours Max. Marks: 75
Note: 1. Question paper consists of three parts (Part-I, Part-II & Part-III)
2. Answer ALL (Multiple Choice) Questions from Part-I
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3. Answer any TWO Questions from Part-II4. Answer any SEVEN Questions from Part-III
PART - I
- (i) b.i.d. means............ (1M)
(a) once a day (b) twice a day (c) thrice a day (d) four times a day - (ii) If the adult dose is 50 mg, then as per Young’s formula, what would be the dose for a one year old kid? (1M)
(a) 0.0384 mg (b) 0.384 mg (c) 3.84 mg (d) 38.4mg - (iii) Emollient is used for ........... (1M)
(a) Wound healing (b) Anti-inflammation
(c) Skin Moisturizing (d) Skin infections - (iv) Lozenges are a type of ...... (1M)
(a) Ointment (b) cream (c) tablet (d) capsule - (v) Which of the following is a cosmetic? (1M)
(a) Crocin syrup (b) Betadine ointment
(c) Clove oil emulsion (d) Cold cream - (vi) Isotonic solutions shall have same.......... (1M)
(a) Viscosity (b) Temperature (c) Surface tension (d) Osmotic pressure - (vii) The term metered dosage is used for’........... (1M)
(a) Lotions (b) Creams (c) Tablets (d) Aerosols - (viii) ............... is often used as a flavoring agent in mouth washes (1M)
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(a) Clove oil (b) Eucalyptus oil (c) Gaultheria oil (d) Menthol - (ix) In solutions particles are (1M)
(a) Invisible (b) visible by naked eye
(c) visible by ordinary microscope (d) visible by electron microscope - (x) Particle size in suspension is (1M)
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(a) less than 10 nm (b) 10 > nm (c) greater than 10 (d) 10 nm - (xi) ............... observed in emulsions is usually reversible (1M)
(a) Breaking (b) Coalescence (c) cracking (d) creaming - (xii) Which of the following surfactants is the most suitable one to prepare an o/w (1M) emulsion
(a) HLB 2.1 (b) HLB 3.4 (c) HLB 13.5 (d) HLB 20.0 - (xiii) ........... does not contain alcohol (1M)
(a) digoxin elixir (b) iodine tincture
(c) flexible collodion (d) Povidone iodine topical solution - (xiv) Which of the following mechanical equipment can be used for emulsification? (1M)
(a) Homogenizers (b) Mechanical stirrers (c) Ultrasonifiers (d) All - (xv) A suppository is generally intended for use in (1M)
(a) Rectum (b) Vagina (c) Urethra (d) All the above - (xvi) The number of milligrams of KOH required neutralizing free acids & saponify the esters contained in 1 g of fat is known as (1M)
(a) Iodine value (b) Saponification value (c) Water (d) Acid value - (xvii) Brownian movement of particles ............... sedimentation (1M)
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(a) Assist (b) Prevent (c) Promote (d) increase - (xviii) Wetting ability of vehicle is detected by observing ......... (1M)
(a) Angle of repose (b) Contact angle
(c) Critical angle (d) None of the above - (xix) Photolabile substance......... (1M)
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(a) Absorbs moisture and liquefy (b) Degrades at room temperature
(c) Degrades upon exposure to light (d) None of the above - (xx) Which of the following theories of emulsification predicts that an emulsifier molecule having a greater hydrophilic than hydrophobic character will promote an o/w emulsion? (1M)
(a) Surface tension theory (b) Oriented wedge theory
(c) Plastic theory (d) Interfacial film theory
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PART - II
- What is a monograph? Write a note on its constitution and significance. (5M)
- Discuss the factors influencing dose of a drug. (5M)
- What are throat paints? Write its preparation and uses. (5M)
- Write methods used for preparation of emulsions. (5M)
- Write in brief on chemical incompatibilities in drugs. (5M)
- Write factors influencing absorption of drug across skin. (5M)
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PART III
- Write methods used for calculation of pediatric drug dose. (5M)
- Write short note on composition of a prescription. (5M)
- Write about the excipients used in liquid dosage form. (5M)
- What are eutectic mixtures? Write their significance in pharmaceutical formulation. (5M)
- Discuss the stability problems of suspensions. (5M)
- Classify emulsions with examples. How do you test for identification of type of emulsion? (5M)
- Write short note on bases used for suppositories (5M)
- Compare and contrast ointment and cream. (5M)
- Discuss the role of pharmacist in hospital and industry. (5M)
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