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149-NR
M.D. DEGREE EXAMINATION — OCTOBER, 2013
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BIOCHEMISTRY
Paper-II : Chemistry and Metabolism.
Time: 3 Hours Max. Marks: 100
Note: Answer all questions
All questions carry equal marks
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WRITE SHORT ESSAYS ON THE FOLLOWING:
- What are essential fatty acids? Enumerate them. Write two functions and one deficiency manifestation?
- Explain irreversible steps of glycolysis with the enzymes involved. Write energetic under aerobic and anaerobic conditions.
- Glucose Alanine cycle.
- What are Immunoglobulins? Name the immunoglobulin which serves as first line of defense.
- Draw a well labelled diagram of DNA structure.
- What are porphyrias? Classify them and discuss acute intermittent Porphyria.
- Inhibitors of oxidative Phosphorylation.
- Discuss the various ways by which ammonia is produced from various metabolites in the body.
- Gluconeogenesis in starvation and well fed state.
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Explain the biochemical basis of Lesch-Nyhan syndrome and Von Gierke’s disease.
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